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Immunology

D-Index
58
Citations
12581
World Ranking
3511
National Ranking
1627

Overview

William H. Hildebrand is affiliated with the University of Oklahoma Health Sciences Center in the United States. Their research primarily spans the fields of Immunology and Microbiology, Medicine, and Biochemistry, Genetics and Molecular Biology, with a strong emphasis on immunological studies.

Their subfields of study include Immunology, Molecular Biology, Oncology, Radiology, Nuclear Medicine and Imaging, and Epidemiology. The main topics of their work cover Immunotherapy and Immune Responses, vaccines and immunoinformatics approaches, Immune Cell Function and Interaction, T-cell and B-cell Immunology, Monoclonal and Polyclonal Antibodies Research, Cancer Immunotherapy and Biomarkers, and Peptidase Inhibition and Analysis.

William H. Hildebrand has published extensively in several scientific venues. The most frequent publication outlets for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Frontiers in Immunology
  • Communications Biology
  • The Journal of Immunology

Recent papers authored by William H. Hildebrand demonstrate a focus on antigen presentation, immunopeptidomics, and the immunogenicity related to HLA molecules. Notable publications include:

  • Improved Prediction of MHC II Antigen Presentation through Integration and Motif Deconvolution of Mass Spectrometry MHC Eluted Ligand Data, 2020, Journal of Proteome Research
  • Accurate prediction of HLA class II antigen presentation across all loci using tailored data acquisition and refined machine learning, 2023, Science Advances
  • Accurate MHC Motif Deconvolution of Immunopeptidomics Data Reveals a Significant Contribution of DRB3, 4 and 5 to the Total DR Immunopeptidome, 2022, Frontiers in Immunology
  • Machine learning reveals limited contribution of trans-only encoded variants to the HLA-DQ immunopeptidome, 2023, Communications Biology
  • Alterations in the HLA-B*57:01 Immunopeptidome by Flucloxacillin and Immunogenicity of Drug-Haptenated Peptides, 2021, Frontiers in Immunology

The scientist has collaborated frequently with a number of co-authors, including:

  • Saghar Kaabinejadian
  • Erin J. Adams
  • Morten Nielsen
  • Hooman Yari
  • David Lewinsohn

Best Publications

  • A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells

    Beatriz M. Carreno;Vincent Magrini;Michelle Becker-Hapak;Saghar Kaabinejadian

  • Impact of HLA class I and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome.

    Neal Flomenberg;Lee Ann Baxter-Lowe;Dennis Confer;Marcelo Fernandez-Vina

  • T cells from patients with Parkinson’s disease recognize α-synuclein peptides

    David Sulzer;Roy N. Alcalay;Francesca Garretti;Lucien Cote

  • Improved Prediction of MHC II Antigen Presentation through Integration and Motif Deconvolution of Mass Spectrometry MHC Eluted Ligand Data

    Birkir Reynisson;Carolina Barra;Saghar Kaabinejadian;William H. Hildebrand

  • MHC-1 Genotypes Restricts The Oncogenic Mutational Landscape

    Joan Font-Burgada;David Rossell;Hannah K. Carter;Rachel Marty

  • Relative Dominance of Gag p24-Specific Cytotoxic T Lymphocytes Is Associated with Human Immunodeficiency Virus Control

    Rosario Zuñiga;Aldo Lucchetti;Patricia Galvan;Shyla Sanchez

  • Unusual HLA-B alleles in two tribes of Brazilian Indians

    M P Belich;J A Madrigal;W H Hildebrand;J Zemmour

  • Abacavir induces loading of novel self-peptides into HLA-B*57:01: an autoimmune model for HLA-associated drug hypersensitivity

    Michael A. Norcross;Shen Luo;Li Lu;Michael T. Boyne

  • Recognition of lyso-phospholipids by human natural killer T lymphocytes.

    Lisa M. Fox;Daryl G. Cox;Jennifer L. Lockridge;Xiaohua Wang

  • The Length Distribution of Class I–Restricted T Cell Epitopes Is Determined by Both Peptide Supply and MHC Allele–Specific Binding Preference

    Thomas Trolle;Curtis P. McMurtrey;John Sidney;Wilfried Bardet

  • Determination of Cellular Lipids Bound to Human CD1d Molecules

    Daryl G Cox;Daryl G Cox;Lisa M Fox;Runying Tian;Wilfried Bardet

  • Definition of the viral targets of protective HIV-1-specific T cell responses.

    Beatriz Mothe;Anuska Llano;F. Javier Ibarrondo;Marcus Daniels

  • T Cell Mimicry and Epitope Specificity of Cross-Reactive T Cell Clones from Rheumatic Heart Disease

    Nadia M. J. Ellis;Ya Li;William Hildebrand;Vincent A. Fischetti

  • Two MHC class I molecules associated with elite control of immunodeficiency virus replication, Mamu-B*08 and HLA-B*2705, bind peptides with sequence similarity.

    John T. Loffredo;John Sidney;Alex T. Bean;Dominic R. Beal

  • MR1 displays the microbial metabolome driving selective MR1-restricted T cell receptor usage

    Melanie J. Harriff;Curtis McMurtrey;Cara A. Froyd;Haihong Jin

  • Toward a definition of self: proteomic evaluation of the class I peptide repertoire.

    Heather D. Hickman;Angela D. Luis;Rico Buchli;Steven R. Few

  • Human Leukocyte Antigen F Presents Peptides and Regulates Immunity through Interactions with NK Cell Receptors.

    Charles L. Dulberger;Curtis P. McMurtrey;Angelique Hölzemer;Angelique Hölzemer;Karlynn E. Neu

  • Structural heterogeneity in HLA‐B70, a high‐frequency antigen of black populations *

    J D Domena;A M Little;A J Madrigal;W H Hildebrand

  • HLA-B15: A widespread and diverse family of HLA-B alleles

    William H. Hildebrand;John D. Domena;Susan Y. Shen;Marie Lau

  • Molecular definition of a polymorphic antigen (LA45) of free HLA-A and -B heavy chains found on the surfaces of activated B and T cells.

    J A Madrigal;M P Belich;R J Benjamin;A M Little

  • Mutually Exclusive T-Cell Receptor Induction and Differential Susceptibility to Human Immunodeficiency Virus Type 1 Mutational Escape Associated with a Two-Amino-Acid Difference between HLA Class I Subtypes

    Xu G. Yu;Mathias Lichterfeld;Senica Chetty;Katie L. Williams

  • Escape in one of two cytotoxic T-lymphocyte epitopes bound by a high-frequency major histocompatibility complex class I molecule, Mamu-A*02: A paradigm for virus evolution and persistence?

    Thorsten U. Vogel;Thomas C. Friedrich;David H. O'Connor;William Rehrauer

Frequent Co-Authors

Alessandro Sette
Alessandro Sette La Jolla Institute For Allergy & Immunology
Peter Parham
Peter Parham Stanford University
Bjoern Peters
Bjoern Peters La Jolla Institute For Allergy & Immunology
Bruce D. Walker
Bruce D. Walker Harvard University
Charles R. Rinaldo
Charles R. Rinaldo University of Pittsburgh
Marcelo Fernandez-Vina
Marcelo Fernandez-Vina Stanford University
David H. O’Connor
David H. O’Connor University of Wisconsin–Madison
David M. Lewinsohn
David M. Lewinsohn Oregon Health & Science University
John Sidney
John Sidney La Jolla Institute For Allergy & Immunology
Frans H.J. Claas
Frans H.J. Claas Leiden University Medical Center

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