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Immunology

D-Index
70
Citations
16263
World Ranking
2431
National Ranking
1163

Overview

David M. Lewinsohn is affiliated with Oregon Health & Science University in the United States. Their research primarily focuses on immunology and microbiology, with a strong emphasis on infectious diseases and pulmonary medicine. Their scientific work encompasses a range of topics related to immune cell functions and interactions, particularly involving T-cell and B-cell immunology.

Their main fields of study include:

  • Immunology and Microbiology
  • Medicine

Within these fields, the subfields of research extend to:

  • Immunology
  • Epidemiology
  • Infectious Diseases
  • Molecular Biology
  • Pulmonary and Respiratory Medicine

The central topics of their work focus on areas such as:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Tuberculosis Research and Epidemiology
  • Immunotherapy and Immune Responses
  • Mycobacterium research and diagnosis
  • Cytomegalovirus and herpesvirus research
  • Immunodeficiency and Autoimmune Disorders

Recent papers by David M. Lewinsohn highlight their ongoing contributions to the body of knowledge in immunology and infectious disease research. Some notable publications include:

  • "The status of tuberculosis vaccine development," 2020, The Lancet Infectious Diseases
  • "Ligand-dependent downregulation of MR1 cell surface expression," 2020, Proceedings of the National Academy of Sciences
  • "Human lung-resident mucosal-associated invariant T cells are abundant, express antimicrobial proteins, and are cytokine responsive," 2022, Communications Biology
  • "Effects of BCG vaccination on donor unrestricted T cells in two prospective cohort studies," 2022, EBioMedicine
  • "Augmentation of the Riboflavin-Biosynthetic Pathway Enhances Mucosa-Associated Invariant T (MAIT) Cell Activation and Diminishes Mycobacterium tuberculosis Virulence," 2022, mBio

Their frequent co-authors include:

  • Gwendolyn Swarbrick
  • Deborah A. Lewinsohn
  • Aneta Worley
  • Meghan Cansler
  • Corinna A. Kulicke

David M. Lewinsohn's work has been published extensively in several scientific venues. They have multiple publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • Scientific Reports
  • The Journal of Immunology
  • Communications Biology

Best Publications

  • Official American Thoracic Society/Infectious Diseases Society of America/Centers for Disease Control and Prevention Clinical Practice Guidelines: Diagnosis of Tuberculosis in Adults and Children

    David M. Lewinsohn;Michael K. Leonard;Philip A. LoBue;David L. Cohn

  • Human Mucosal Associated Invariant T Cells Detect Bacterially Infected Cells

    Marielle C. Gold;Marielle C. Gold;Stefania Cerri;Susan Smyk-Pearson;Meghan E. Cansler

  • Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis

    Kristi M. Guinn;Mark J. Hickey;Sanjeev K. Mathur;Kelly L. Zakel

  • Vitamin D Is Required for IFN-γ–Mediated Antimicrobial Activity of Human Macrophages

    Mario Fabri;Steffen Stenger;Dong Min Shin;Jae Min Yuk

  • Incipient and Subclinical Tuberculosis: a Clinical Review of Early Stages and Progression of Infection.

    Paul K. Drain;Kristina L. Bajema;David Dowdy;Keertan Dheda

  • Leukocyte-endothelial cell recognition: evidence of a common molecular mechanism shared by neutrophils, lymphocytes, and other leukocytes.

    D M Lewinsohn;R F Bargatze;E C Butcher

  • Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization.

    Hannah Priyadarshini Gideon;Jia Yao Phuah;Amy J. Myers;Bryan D. Bryson

  • Cytomegalovirus US2 destroys two components of the MHC class II pathway, preventing recognition by CD4+ T cells

    Roman Tomazin;Jessica Boname;Jessica Boname;Nagendra R. Hegde;David M. Lewinsohn

  • HLA-E-dependent presentation of Mtb-derived antigen to human CD8+ T cells.

    Amy S. Heinzel;Jeff E. Grotzke;Jeff E. Grotzke;Rebecca A. Lines;Deborah A. Lewinsohn

  • Frequencies of HCV‐specific effector CD4+ T cells by flow cytometry: Correlation with clinical disease stages

    Hugo R. Rosen;Camette Miner;Anna W. Sasaki;David M. Lewinsohn

  • Immune evasion versus recovery after acute hepatitis C virus infection from a shared source

    Ian Tester;Susan Smyk-Pearson;Susan Smyk-Pearson;Ping Wang;Anne Wertheimer

  • CHARACTERIZATION OF HUMAN CD8+ T CELLS REACTIVE WITH MYCOBACTERIUM TUBERCULOSIS-INFECTED ANTIGEN-PRESENTING CELLS

    David M. Lewinsohn;David M. Lewinsohn;Mark R. Alderson;Andria L. Briden;Stanley R. Riddell

  • MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage

    Marielle C. Gold;James E. McLaren;Joseph A. Reistetter;Sue Smyk-Pearson

  • Molecular characterization and human T-cell responses to a member of a novel Mycobacterium tuberculosis mtb39 gene family

    Davin C. Dillon;Mark R. Alderson;Craig H. Day;David M. Lewinsohn

  • Mycobacterium tuberculosis-specific CD8+ T Cells Preferentially Recognize Heavily Infected Cells

    Deborah A. Lewinsohn;Amy S. Heinzel;James M. Gardner;Liqing Zhu

  • Polyfunctional CD4+ T Cells As Targets for Tuberculosis Vaccination

    Deborah A. Lewinsohn;David M. Lewinsohn;Thomas J. Scriba

  • Immunodominant tuberculosis CD8 antigens preferentially restricted by HLA-B

    Deborah A Lewinsohn;Ervina Winata;Ervina Winata;Gwendolyn M Swarbrick;Gwendolyn M Swarbrick;Katie E Tanner;Katie E Tanner

  • Identification of a Human HLA-E-Restricted CD8+ T Cell Subset in Volunteers Immunized with Salmonella enterica Serovar Typhi Strain Ty21a Typhoid Vaccine

    Rosângela Salerno-Gonçalves;Marcelo Fernandez-Viña;David M. Lewinsohn;Marcelo B. Sztein

  • Expression Cloning of an Immunodominant Family of Mycobacterium tuberculosis Antigens Using Human Cd4+ T Cells

    Mark R. Alderson;Teresa Bement;Craig H. Day;Liqing Zhu

  • Role of CD8+ T lymphocytes in control of Mycobacterium tuberculosis infection

    Jeff E. Grotzke;David M. Lewinsohn

  • Human thymic MR1-restricted MAIT cells are innate pathogen-reactive effectors that adapt following thymic egress

    Marielle C. Gold;Tarek Eid;Sue Smyk-Pearson;Yvonne Eberling

Frequent Co-Authors

Mark R. Alderson
Mark R. Alderson Program for Appropriate Technology in Health
Eugene C. Butcher
Eugene C. Butcher Stanford University
Hugo R. Rosen
Hugo R. Rosen University of Southern California
William H. Hildebrand
William H. Hildebrand University of Oklahoma Health Sciences Center
Thomas J. Scriba
Thomas J. Scriba University of Cape Town
Jamie Rossjohn
Jamie Rossjohn Monash University
Willem A. Hanekom
Willem A. Hanekom University College London
David R. Sherman
David R. Sherman University of Washington
W. Henry Boom
W. Henry Boom Case Western Reserve University

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