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Immunology

D-Index
139
Citations
72575
World Ranking
167
National Ranking
16

Medicine

D-Index
139
Citations
72658
World Ranking
1760
National Ranking
184

Research.com Recognitions

  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom

Overview

Paul Klenerman is affiliated with the University of Oxford in the United Kingdom. Their research primarily focuses on the fields of Medicine and Immunology and Microbiology, with a substantial number of publications addressing Infectious Diseases, Immunology, Epidemiology, Molecular Biology, and Oncology.

The main topics Paul Klenerman has investigated include SARS-CoV-2 and COVID-19 Research, COVID-19 Clinical Research Studies, Immune Cell Function and Interaction, T-cell and B-cell Immunology, Immunotherapy and Immune Responses, Long-Term Effects of COVID-19, and vaccines and immunoinformatics approaches.

Frequent venues where their research has been published encompass bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, SSRN Electronic Journal, Cell, and Frontiers in Immunology.

Key recent papers include the following:

  • Genetic mechanisms of critical illness in COVID-19, 2020, Nature
  • Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19, 2020, Nature Immunology
  • Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine-induced sera, 2021, Cell
  • SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses, 2022, Cell
  • Antibody escape of SARS-CoV-2 Omicron BA.4 and BA.5 from vaccine and BA.1 serum, 2022, Cell

Paul Klenerman has collaborated frequently with several co-authors, including:

  • Eleanor Barnes
  • Susanna Dunachie
  • Alexander J. Mentzer
  • Lance Turtle
  • J. Kenneth Baillie

They have received recognition as a Fellow of The Academy of Medical Sciences, United Kingdom.

Best Publications

  • PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

    Cheryl L Day;Daniel E Kaufmann;Photini Kiepiela;Julia A Brown

  • Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections.

    Victor Appay;P. Rod Dunbar;Margaret Callan;Paul Klenerman

  • Analysis of Successful Immune Responses in Persons Infected with Hepatitis C Virus

    F. Lechner;D. K. H. Wong;P. R. Dunbar;R. Chapman

  • The Human Cell Atlas

    Aviv Regev;Aviv Regev;Aviv Regev;Sarah A Teichmann;Sarah A Teichmann;Sarah A Teichmann;Eric S Lander;Eric S Lander;Eric S Lander;Ido Amit

  • Genetic mechanisms of critical illness in Covid-19.

    E. Pairo-Castineira;E. Pairo-Castineira;S. Clohisey;L. Klaric;A. D. Bretherick

  • Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials.

    M Voysey;S A Costa Clemens;S A Madhi;L Y Weckx

  • Broad and strong memory CD4 + and CD8 + T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19.

    Y Peng;A J Mentzer;G Liu;G Liu;X Yao

  • Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine-induced sera.

    D Zhou;W Dejnirattisai;P Supasa;C Liu

  • Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.

    Photini Kiepiela;Alasdair J. Leslie;Isobella Honeyborne;Danni Ramduth

  • POSITIVE SELECTION OF HIV-1 CYTOTOXIC T LYMPHOCYTE ESCAPE VARIANTS DURING PRIMARY INFECTION

    David A. Price;Philip J. R. Goulder;Paul Klenerman;Andrew K. Sewell

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Andreas Acs

  • COVID-19 vaccine coverage in health-care workers in England and effectiveness of BNT162b2 mRNA vaccine against infection (SIREN): a prospective, multicentre, cohort study.

    Victoria Jane Hall;Victoria Jane Hall;Sarah Foulkes;Ayoub Saei;Nick Andrews;Nick Andrews

  • SARS-CoV-2 infection rates of antibody-positive compared with antibody-negative health-care workers in England: a large, multicentre, prospective cohort study (SIREN).

    V J Hall;S Foulkes;A Charlett;A Atti

  • Reduced neutralization of SARS-CoV-2 B.1.617 by vaccine and convalescent serum.

    C Liu;H M Ginn;W Dejnirattisai;P Supasa

  • Genome-wide genetic association of complex traits in heterogeneous stock mice

    William Valdar;Leah C Solberg;Leah C Solberg;Dominique Gauguier;Stephanie Burnett

  • Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study.

    Rachael A Evans;Hamish McAuley;Ewen M Harrison;Aarti Shikotra

  • Sustained Dysfunction of Antiviral CD8+ T Lymphocytes after Infection with Hepatitis C Virus

    Norbert H. Gruener;Franziska Lechner;Maria-Christina Jung;Helmut Diepolder

  • Medium-term effects of SARS-CoV-2 infection on multiple vital organs, exercise capacity, cognition, quality of life and mental health, post-hospital discharge

    B Raman;B Raman;M P Cassar;E M Tunnicliffe;N Filippini

  • CD161 ++ CD8 + T cells, including the MAIT cell subset, are specifically activated by IL-12+IL-18 in a TCR-independent manner

    James E. Ussher;Matthew Bilton;Emma Attwod;Jonathan Shadwell

  • Immune surveillance against a solid tumor fails because of immunological ignorance.

    Adrian F. Ochsenbein;Paul Klenerman;Urs Karrer;Burkhard Ludewig

  • Antibody evasion by the P.1 strain of SARS-CoV-2.

    W Dejnirattisai;D Zhou;P Supasa;C Liu

  • Adaptation of HIV-1 to human leukocyte antigen class I

    Y. Kawashima;K. Pfafferott;J. Frater;P. Matthews

  • Memory Inflation: Continuous Accumulation of Antiviral CD8+ T Cells Over Time

    Urs Karrer;Sophie Sierro;Markus Wagner;Annette Oxenius

  • Direct ex vivo analysis of antigen-specific IFN-gamma-secreting CD4 T cells in Mycobacterium tuberculosis-infected individuals: associations with clinical disease state and effect of treatment.

    Ansar A. Pathan;Katalin A. Wilkinson;Paul Klenerman;Helen McShane

  • Lancet Seminar – Hepatitis C

    Daniel P Webster;Paul Klenerman;Geoffrey M Dusheiko

  • Genetic mechanisms of critical illness in Covid-19

    Erola Pairo-Castineira;Sara Clohisey;Lucija Klaric;Andrew Bretherick;Andrew Bretherick

Frequent Co-Authors

Eleanor Barnes
Eleanor Barnes University of Oxford
Philip J. R. Goulder
Philip J. R. Goulder University of Oxford
Rodney E. Phillips
Rodney E. Phillips University of Oxford
Bruce D. Walker
Bruce D. Walker Harvard University
Philippa C. Matthews
Philippa C. Matthews University of Oxford
Peter Simmonds
Peter Simmonds University of Oxford
John Frater
John Frater University of Oxford
Georg M. Lauer
Georg M. Lauer Harvard University
Oliver G. Pybus
Oliver G. Pybus University of Oxford
Silvana Gaudieri
Silvana Gaudieri University of Western Australia

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