2023 - Research.com Immunology in United Kingdom Leader Award
Fellow of The Academy of Medical Sciences, United Kingdom
Paul Klenerman focuses on Immunology, Virology, Cytotoxic T cell, CD8 and Immune system. His Hepatitis C virus, Antigen, T cell, Immunity and Human leukocyte antigen study are his primary interests in Immunology. His research in Virology is mostly concerned with Virus.
His Cytotoxic T cell research is multidisciplinary, incorporating perspectives in Molecular biology and Effector. His CD8 research integrates issues from T lymphocyte, Mucosal associated invariant T cell, T-cell receptor, Phenotype and Cell biology. His Immune system research is multidisciplinary, relying on both Interferon, Cell culture, Antibody and Hepatitis B virus.
His primary scientific interests are in Immunology, Virology, Cytotoxic T cell, Immune system and CD8. His Immunology study focuses mostly on T cell, Antigen, Hepatitis C, Immunity and CTL*. His Virology research is multidisciplinary, incorporating elements of Epitope and Human leukocyte antigen.
His Cytotoxic T cell research incorporates elements of Major histocompatibility complex and Cell biology. The CD8 study combines topics in areas such as Phenotype and Mucosal associated invariant T cell, T-cell receptor. His studies deal with areas such as Antibody and Lymphocytic choriomeningitis as well as Virus.
Immunology, Immune system, Virology, CD8 and T cell are his primary areas of study. His Immunology research includes elements of Receptor and In vivo. Paul Klenerman has researched Immune system in several fields, including Cell, Cytokine and Antigen.
The Virus, Vaccination and Hepatitis C virus research Paul Klenerman does as part of his general Virology study is frequently linked to other disciplines of science, such as Severe acute respiratory syndrome coronavirus 2, therefore creating a link between diverse domains of science. He combines subjects such as Cytotoxic T cell and Cell biology with his study of CD8. His research in T cell intersects with topics in Immune checkpoint, Cancer research, Peripheral blood mononuclear cell, Disease and Epitope.
The scientist’s investigation covers issues in Antibody, Immunology, CD8, Virology and T cell. His Immunology research includes themes of Disease and In vivo. Paul Klenerman interconnects Cytotoxic T cell, Cell biology and T-cell receptor in the investigation of issues within CD8.
His work deals with themes such as Phenotype and Autoimmunity, which intersect with Cytotoxic T cell. His study in the field of Virus and Viral load is also linked to topics like Severe acute respiratory syndrome coronavirus 2. His T cell course of study focuses on Antigen and Immune checkpoint and Single-cell analysis.
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PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
Cheryl L Day;Daniel E Kaufmann;Photini Kiepiela;Julia A Brown.
Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial
P M Folegatti;K J Ewer;P K Aley;B Angus.
The Lancet (2020)
Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections.
Victor Appay;P. Rod Dunbar;Margaret Callan;Paul Klenerman.
Nature Medicine (2002)
Analysis of Successful Immune Responses in Persons Infected with Hepatitis C Virus
F. Lechner;D. K. H. Wong;P. R. Dunbar;R. Chapman.
Journal of Experimental Medicine (2000)
The Human Cell Atlas
Aviv Regev;Aviv Regev;Aviv Regev;Sarah A Teichmann;Sarah A Teichmann;Sarah A Teichmann;Eric S Lander;Eric S Lander;Eric S Lander;Ido Amit.
Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.
Photini Kiepiela;Alasdair J. Leslie;Isobella Honeyborne;Danni Ramduth.
POSITIVE SELECTION OF HIV-1 CYTOTOXIC T LYMPHOCYTE ESCAPE VARIANTS DURING PRIMARY INFECTION
David A. Price;Philip J. R. Goulder;Paul Klenerman;Andrew K. Sewell.
Proceedings of the National Academy of Sciences of the United States of America (1997)
Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials.
M Voysey;S A Costa Clemens;S A Madhi;L Y Weckx.
The Lancet (2021)
Broad and strong memory CD4 + and CD8 + T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19.
Y Peng;A J Mentzer;G Liu;G Liu;X Yao.
Nature Immunology (2020)
Genetic mechanisms of critical illness in Covid-19.
E. Pairo-Castineira;E. Pairo-Castineira;S. Clohisey;L. Klaric;A. D. Bretherick.
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