World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
103
Citations
41191
World Ranking
638
National Ranking
38

Medicine

D-Index
103
Citations
41191
World Ranking
7334
National Ranking
413

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Marcus Altfeld is affiliated with the Heinrich-Pette-Institute in Germany. Their research spans multiple disciplines within biomedical sciences, focusing predominantly on immunology and microbiology, with significant contributions to medicine. Their work covers a range of subfields, including immunology, virology, infectious diseases, hepatology, and molecular biology.

The scientist's main research topics involve immune cell function and interaction, T-cell and B-cell immunology, HIV research and treatment, reproductive system and pregnancy, immunotherapy and immune responses, liver diseases and immunity, and immune response and inflammation.

Marcus Altfeld has published extensively in several frequent venues. Notable publication venues include:

  • Frontiers in Immunology
  • Nature Communications
  • Journal of Hepatology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports

Significant recent papers authored or co-authored by Marcus Altfeld include:

  • "Implications of Sex Differences in Immunity for SARS-CoV-2 Pathogenesis and Design of Therapeutic Interventions," 2020, Immunity
  • "Heterogeneous Escape from X Chromosome Inactivation Results in Sex Differences in Type I IFN Responses at the Single Human pDC Level," 2020, Cell Reports
  • "Single-cell atlas of hepatic T cells reveals expansion of liver-resident naive-like CD4+ T cells in primary sclerosing cholangitis," 2021, Journal of Hepatology
  • "Kupffer cell-like syncytia replenish resident macrophage function in the fibrotic liver," 2023, Science
  • "Natural killer cell-mediated ADCC in SARS-CoV-2-infected individuals and vaccine recipients," 2022, European Journal of Immunology

Frequent collaborators with Marcus Altfeld consist of:

  • Madeleine J. Bunders
  • Sven Hendrik Hagen
  • Glòria Martrus
  • Annika Niehrs
  • Laura Richert

Marcus Altfeld has been recognized as a Member of the Association of American Physicians.

Best Publications

  • PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

    Cheryl L Day;Daniel E Kaufmann;Photini Kiepiela;Julia A Brown

  • CD107a as a functional marker for the identification of natural killer cell activity

    Galit Alter;Jessica M. Malenfant;Marcus Altfeld

  • The major genetic determinants of HIV-1 control affect HLA class I peptide presentation

    Pereyra F;Jia X;McLaren Pj

  • Immune control of HIV-1 after early treatment of acute infection

    Eric S. Rosenberg;Marcus Altfeld;Samuel H. Poon;Mary N. Phillips

  • HIV evolution: CTL escape mutation and reversion after transmission.

    A J Leslie;K J Pfafferott;P Chetty;R Draenert

  • Comprehensive Epitope Analysis of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T-Cell Responses Directed against the Entire Expressed HIV-1 Genome Demonstrate Broadly Directed Responses, but No Correlation to Viral Load

    M. M. Addo;X. G. Yu;A. Rathod;D. Cohen

  • Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.

    Photini Kiepiela;Alasdair J. Leslie;Isobella Honeyborne;Danni Ramduth

  • Evolution and transmission of stable CTL escape mutations in HIV infection

    Philip J. R. Goulder;Christian Brander;Yanhua Tang;Cecile Tremblay

  • Sex differences in the Toll-like receptor–mediated response of plasmacytoid dendritic cells to HIV-1

    Angela Meier;J Judy Chang;Ellen S Chan;Richard B Pollard

  • Differential natural killer cell–mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes

    Galit Alter;Maureen P. Martin;Nickolas Teigen;William H Carr

  • Cellular Immune Responses and Viral Diversity in Individuals Treated during Acute and Early HIV-1 Infection

    Marcus Altfeld;Eric S. Rosenberg;Raj Shankarappa;Joia S. Mukherjee

  • Control of Human Viral Infections by Natural Killer Cells

    Stephanie Jost;Marcus Altfeld

  • Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe

    Selidji T Agnandji;Angela Huttner;Madeleine E Zinser;Patricia Njuguna

  • Antiretroviral-Free HIV-1 Remission and Viral Rebound After Allogeneic Stem Cell Transplantation: Report of 2 Cases

    Timothy J. Henrich;Emily Hanhauser;Francisco M. Marty;Michael N. Sirignano

  • Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection.

    Marcus Altfeld;Marylyn M. Addo;Eric S. Rosenberg;Frederick M. Hecht

  • Loss of HIV-1–specific CD8+ T Cell Proliferation after Acute HIV-1 Infection and Restoration by Vaccine-induced HIV-1–specific CD4+ T Cells

    Mathias Lichterfeld;Daniel E. Kaufmann;Xu G. Yu;Stanley K. Mui

  • HIV-1 superinfection despite broad CD8 + T-cell responses containing replication of the primary virus

    Marcus Altfeld;Todd M. Allen;Xu G. Yu;Mary N. Johnston

  • HIV-1 adaptation to NK-cell-mediated immune pressure

    Galit Alter;David Heckerman;Arne Schneidewind;Lena Fadda

  • Sequential deregulation of NK cell subset distribution and function starting in acute HIV-1 infection

    Galit Alter;Nickolas Teigen;Benjamin T. Davis;Marylyn M. Addo

  • Characteristics of the Earliest Cross-Neutralizing Antibody Response to HIV-1

    Iliyana Mikell;D. Noah Sather;Spyros A. Kalams;Marcus Altfeld

Frequent Co-Authors

Bruce D. Walker
Bruce D. Walker Harvard University
Philip J. R. Goulder
Philip J. R. Goulder University of Oxford
Eric S. Rosenberg
Eric S. Rosenberg Harvard University
Todd M. Allen
Todd M. Allen Harvard University
Marylyn M. Addo
Marylyn M. Addo Universität Hamburg
Xu G. Yu
Xu G. Yu Ragon Institute of MGH, MIT and Harvard
Mary Carrington
Mary Carrington Ragon Institute of MGH, MIT and Harvard
Hendrik Streeck
Hendrik Streeck University Hospital Bonn
Christian Brander
Christian Brander University of Vic - Central University of Catalonia

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