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Immunology

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79
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30272
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1663
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143

Medicine

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Research.com Recognitions

  • 1953 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Eleanor Barnes is affiliated with the University of Oxford in the United Kingdom and has made significant contributions to the field of medical research, particularly in infectious diseases, immunology, and hepatology. Their work spans multiple subfields including infectious diseases, epidemiology, hepatology, immunology, and molecular biology. The main focus of their research lies in the study of SARS-CoV-2 and COVID-19, liver disease diagnosis and treatment, and hepatitis viruses.

Their recent publications include studies on the immunogenicity and vaccine efficacy against SARS-CoV-2, immune memory responses following COVID-19 infection, and the ability of viral variants to escape immune responses. Notable papers are:

  • Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial, 2020, The Lancet
  • Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19, 2020, Nature Immunology
  • Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine-induced sera, 2021, Cell
  • SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses, 2022, Cell
  • Antibody escape of SARS-CoV-2 Omicron BA.4 and BA.5 from vaccine and BA.1 serum, 2022, Cell

Eleanor Barnes collaborates regularly with researchers across a range of scientific topics. Their most frequent coauthors include Paul Klenerman, Susanna Dunachie, Philippa C. Matthews, M. Azim Ansari, and Miles W. Carroll.

Their research has been published extensively in venues such as bioRxiv (Cold Spring Harbor Laboratory), Journal of Hepatology, Wellcome Open Research, UNC Libraries, and SSRN Electronic Journal.

Their academic contributions cover several key topics:

  • SARS-CoV-2 and COVID-19 Research
  • Liver Disease Diagnosis and Treatment
  • Hepatitis C virus research
  • Hepatitis B Virus Studies
  • COVID-19 Clinical Research Studies
  • Liver Disease and Transplantation
  • Immunotherapy and Immune Responses

Their expertise in medicine has been acknowledged with the award of Fellow of the American Association for the Advancement of Science (AAAS) in 1953.

Best Publications

  • Global Distribution and Prevalence of Hepatitis C Virus Genotypes

    Jane P. Messina;Isla Humphreys;Abraham Flaxman;Anthony Brown

  • SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses

    Unknown

  • Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials.

    M Voysey;S A Costa Clemens;S A Madhi;L Y Weckx

  • Broad and strong memory CD4 + and CD8 + T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19.

    Y Peng;A J Mentzer;G Liu;G Liu;X Yao

  • Antibody escape of SARS-CoV-2 Omicron BA.4 and BA.5 from vaccine and BA.1 serum

    Unknown

  • Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine-induced sera.

    D Zhou;W Dejnirattisai;P Supasa;C Liu

  • Reduced neutralization of SARS-CoV-2 B.1.617 by vaccine and convalescent serum.

    C Liu;H M Ginn;W Dejnirattisai;P Supasa

  • Antibody evasion by the P.1 strain of SARS-CoV-2.

    W Dejnirattisai;D Zhou;P Supasa;C Liu

  • Accelerating the elimination of viral hepatitis: a Lancet Gastroenterology & Hepatology Commission

    Graham S Cooke;Isabelle Andrieux-Meyer;Tanya L Applegate;Rifat Atun

  • Multiparametric magnetic resonance for the non-invasive diagnosis of liver disease.

    Rajarshi Banerjee;Michael Pavlides;Elizabeth M. Tunnicliffe;Stefan K. Piechnik

  • MAIT cells are activated during human viral infections

    B van Wilgenburg;I Scherwitzl;E C Hutchinson;T Leng

  • Outcomes following SARS-CoV-2 infection in patients with chronic liver disease: an international registry study.

    Thomas Marjot;Andrew M. Moon;Jonathan A. Cook;Sherief Abd-Elsalam

  • Novel adenovirus-based vaccines induce broad and sustained T cell responses to HCV in man

    Eleanor Barnes;Eleanor Barnes;Antonella Folgori;Stefania Capone;Leo Swadling

  • A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

    Unknown

  • Reduced neutralization of SARS-CoV-2 B.1.1.7 variant by convalescent and vaccine sera.

    P Supasa;D Zhou;W Dejnirattisai;C Liu

  • Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties.

    Eva Billerbeck;Yu Hoi Kang;Lucy Walker;Helen Lockstone

  • A human vaccine strategy based on chimpanzee adenoviral and MVA vectors that primes, boosts, and sustains functional HCV-specific T cell memory.

    Leo Swadling;Stefania Capone;Richard D. Antrobus;Anthony Brown

  • High resolution analysis of cellular immune responses in resolved and persistent hepatitis C virus infection

    Georg M. Lauer;Eleanor Barnes;Eleanor Barnes;Michaela Lucas;Joerg Timm

  • Performance characteristics of five immunoassays for SARS-CoV-2: a head-to-head benchmark comparison

    M Ainsworth;M Andersson;M Andersson;K Auckland;J K Baillie

  • COVID-19 and liver disease: mechanistic and clinical perspectives.

    Thomas Marjot;Gwilym J. Webb;Alfred S. Barritt;Andrew M. Moon

  • Vaccine Vectors Derived from a Large Collection of Simian Adenoviruses Induce Potent Cellular Immunity Across Multiple Species

    Stefano Colloca;Eleanor Barnes;Antonella Folgori;Virginia Ammendola

  • Efficacy of Sofosbuvir Plus Ribavirin With or Without Peginterferon-Alfa in Patients With Hepatitis C Virus Genotype 3 Infection and Treatment-Experienced Patients With Cirrhosis and Hepatitis C Virus Genotype 2 Infection

    Graham R. Foster;Stephen Pianko;Ashley Brown;Daniel Forton

  • Single Dose Administration, And The Influence Of The Timing Of The Booster Dose On Immunogenicity and Efficacy Of ChAdOx1 nCoV-19 (AZD1222) Vaccine (preprint)

    Voysey, Merryn, Costa Clemens, Sue Ann, Madhi, Shabir A.;Weckx, Lily Yin, Folegatti, Pedro M.;Parvinder K. Aley;Angus, Brian John, Baillie, Vicky, Barnabas, Shaun L.

Frequent Co-Authors

Paul Klenerman
Paul Klenerman University of Oxford
Philippa C. Matthews
Philippa C. Matthews University of Oxford
Stefan Neubauer
Stefan Neubauer University of Oxford
Andrew J. Pollard
Andrew J. Pollard University of Oxford
Peter Simmonds
Peter Simmonds University of Oxford
Rory Bowden
Rory Bowden Walter and Eliza Hall Institute of Medical Research
Juthathip Mongkolsapaya
Juthathip Mongkolsapaya University of Oxford
Susanna Dunachie
Susanna Dunachie University of Oxford
Graham S Cooke
Graham S Cooke Imperial College London
Miles W. Carroll
Miles W. Carroll University of Oxford

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