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Immunology
Singapore
2022

D-Index & Metrics

Immunology

D-Index
95
Citations
36725
World Ranking
889
National Ranking
4

Medicine

D-Index
95
Citations
36728
World Ranking
9990
National Ranking
28

Research.com Recognitions

  • 2022 - Research.com Immunology in Singapore Leader Award

Overview

Antonio Bertoletti is affiliated with Duke NUS Graduate Medical School in Singapore. Their research primarily addresses topics within Medicine, with a focus on Infectious Diseases, Immunology, Epidemiology, Hepatology, and Oncology.

Their recent papers cover critical areas related to SARS-CoV-2 and COVID-19, including immune responses and disease progression:

  • "SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls" (2020, Nature)
  • "Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients" (2021, Cell Reports)
  • "Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease" (2021, Immunity)
  • "Dynamics of SARS-CoV-2 neutralising antibody responses and duration of immunity: a longitudinal study" (2021, The Lancet Microbe)
  • "Highly functional virus-specific cellular immune response in asymptomatic SARS-CoV-2 infection" (2021, The Journal of Experimental Medicine)

The main research topics Antonio Bertoletti has contributed to include:

  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Hepatitis B Virus Studies
  • Hepatitis C virus research
  • CAR-T cell therapy research
  • Long-Term Effects of COVID-19
  • Immunotherapy and Immune Responses

Their frequent coauthors include:

  • Anthony T. Tan
  • Nina Le Bert
  • Jenny G. Low
  • Adeline Chia
  • Shou Kit Hang

Antonio Bertoletti has published extensively in several scientific venues, particularly:

  • Journal of Hepatology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Viral Hepatitis
  • The Journal of Experimental Medicine
  • SSRN Electronic Journal

The distribution of publications reflects a strong focus on infectious diseases and immunological responses, especially relating to viral hepatitis and COVID-19. Their work includes both clinical studies and cellular-level investigations, contributing to understanding viral immunity and long-term effects of infections.

Best Publications

  • SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls.

    Nina Le Bert;Anthony T Tan;Kamini Kunasegaran;Christine Y L Tham

  • Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection.

    Carolina Boni;Paola Fisicaro;Caterina Valdatta;Barbara Amadei

  • The role of virus-specific CD8(+) cells in liver damage and viral control during persistent hepatitis B virus infection.

    Mala K. Maini;Carolina Boni;Chun Kyon Lee;Juan R. Larrubia

  • Human Tissues Contain CD141hi Cross-Presenting Dendritic Cells with Functional Homology to Mouse CD103+ Nonlymphoid Dendritic Cells

    Muzlifah Haniffa;Muzlifah Haniffa;Amanda Shin;Venetia Bigley;Naomi McGovern

  • Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients.

    Anthony T. Tan;Martin Linster;Chee Wah Tan;Nina Le Bert

  • Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells

    Antonio Bertoletti;Alessandro Sette;Francis V. Chisari;Amalia Penna

  • Cellular immune response to hepatitis B virus-encoded antigens in acute and chronic hepatitis B virus infection.

    C Ferrari;A Penna;A Bertoletti;A Valli

  • Therapeutic strategies for hepatitis B virus infection: towards a cure

    Gregory C Fanning;Fabien Zoulim;Jinlin Hou;Antonio Bertoletti

  • Incubation phase of acute hepatitis B in man: dynamic of cellular immune mechanisms

    George J.M. Webster;Stephanie Reignat;Mala K. Maini;Simon A. Whalley

  • Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease.

    Kevin Mulder;Kevin Mulder;Kevin Mulder;Amit Ashok Patel;Amit Ashok Patel;Wan Ting Kong;Cécile Piot

  • The immune response during hepatitis B virus infection.

    Antonio Bertoletti;Adam J. Gehring

  • Lamivudine treatment can restore T cell responsiveness in chronic hepatitis B.

    Carolina Boni;Antonio Bertoletti;Amalia Penna;Albertina Cavalli

  • Innate and adaptive immune responses in chronic hepatitis B virus infections: towards restoration of immune control of viral infection.

    Antonio Bertoletti;Carlo Ferrari

  • Adaptive immunity in HBV infection.

    Antonio Bertoletti;Antonio Bertoletti;Carlo Ferrari

  • Update of the statements on biology and clinical impact of occult hepatitis B virus infection

    Giovanni Raimondo;Stephen Locarnini;Teresa Pollicino;Massimo Levrero

  • Cytokines induced during chronic hepatitis B virus infection promote a pathway for NK cell–mediated liver damage

    Claire Dunn;R. Maurizia Brunetto;Gary Reynolds;Theodoros Christophides

  • HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant

    William S. Mason;Upkar S. Gill;Samuel Litwin;Yan Zhou

  • Direct ex vivo analysis of hepatitis B virus-specific CD8+ T cells associated with the control of infection

    Mala K. Maini;Carolina Boni;Graham S. Ogg;Abigail S. King

  • Longitudinal Analysis of CD8+ T Cells Specific for Structural and Nonstructural Hepatitis B Virus Proteins in Patients with Chronic Hepatitis B: Implications for Immunotherapy

    George J. M. Webster;Stephanie Reignat;David Brown;Graham S. Ogg

  • Lamivudine treatment can overcome cytotoxic T-cell hyporesponsiveness in chronic hepatitis B: New perspectives for immune therapy

    Carolina Boni;Amalia Penna;Graham S. Ogg;Antonio Bertoletti

  • Different cytokine profiles of intraphepatic T cells in chronic hepatitis B and hepatitis C virus infections

    A Bertoletti;MM D'Elios;C Boni;M De Carli

  • Cytotoxic T lymphocytes recognize an HLA-A2-restricted epitope within the hepatitis B virus nucleocapsid antigen.

    A Penna;F V Chisari;A Bertoletti;G Missale

  • IL-1β Production through the NLRP3 Inflammasome by Hepatic Macrophages Links Hepatitis C Virus Infection with Liver Inflammation and Disease

    Amina A. Negash;Hilario J. Ramos;Nanette Crochet;Daryl Tan-Yeung Lau

Frequent Co-Authors

Mala K. Maini
Mala K. Maini University College London
Carlo Ferrari
Carlo Ferrari University of Parma
Graham S. Ogg
Graham S. Ogg University of Oxford
Gabriele Missale
Gabriele Missale University of Parma
Evan W. Newell
Evan W. Newell Fred Hutchinson Cancer Research Center
Roger Williams
Roger Williams Foundation for Liver Research
Yee-Joo Tan
Yee-Joo Tan National University of Singapore
Florent Ginhoux
Florent Ginhoux Agency for Science, Technology and Research
Muzlifah Haniffa
Muzlifah Haniffa Newcastle University

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