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Immunology
USA
2026

D-Index & Metrics

Immunology

D-Index
149
Citations
81609
World Ranking
125
National Ranking
82

Medicine

D-Index
149
Citations
81733
World Ranking
1207
National Ranking
697

Research.com Recognitions

  • 2026 - Research.com Immunology in United States Leader Award
  • 2025 - Research.com Immunology in United States Leader Award
  • 2003 - Member of the National Academy of Medicine (NAM)
  • 2002 - Member of the National Academy of Sciences
  • 1996 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Francis V. Chisari is affiliated with the Scripps Research Institute in the United States. Their research spans the field of Medicine, with a focus on subfields including Epidemiology, Hepatology, Immunology, and Infectious Diseases.

Their work covers several main topics, notably Hepatitis B Virus Studies, Hepatitis C virus research, Immunotherapy and Immune Responses, Immune Cell Function and Interaction, Viral gastroenteritis research and epidemiology, Hepatitis Viruses Studies and Epidemiology, and Liver Disease Diagnosis and Treatment.

Chisari has published in various academic venues, including:

  • The Journal of Experimental Medicine
  • JHEP Reports
  • The Lancet. Gastroenterology & hepatology
  • Journal of Hepatology

Frequent coauthors in Chisari's research include Valeria Fumagalli, Pietro Di Lucia, Luca G. Guidotti, Matteo Iannacone, and Valentina Venzin.

Selected recent papers authored or coauthored by Chisari include:

  • Serum HBsAg clearance has minimal impact on CD8+ T cell responses in mouse models of HBV infection, 2020, The Journal of Experimental Medicine
  • Preclinical evaluation of therapeutic vaccines for chronic hepatitis B that stimulate antiviral activities of T cells and NKT cells, 2024, JHEP Reports
  • Joint statement in support of hepatitis C human challenge studies, 2023, The Lancet. Gastroenterology & hepatology
  • Extracellular HBsAg clearance has minimal impact on CD8+ T cell responses in mouse models of HBV pathogenesis, 2020, Journal of Hepatology

Chisari has been recognized by major organizations, including election as a Member of the National Academy of Sciences in 2002 and the National Academy of Medicine in 2003. Additionally, they were named a Fellow of the American Association for the Advancement of Science in 1996.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Hepatitis B virus immunopathogenesis

    Francis V. Chisari;Carlo Ferrari

  • Robust hepatitis C virus infection in vitro

    Jin Zhong;Pablo Gastaminza;Guofeng Cheng;Sharookh Kapadia

  • Viral Clearance Without Destruction of Infected Cells During Acute HBV Infection

    Luca G. Guidotti;Rosemary Rochford;Josan Chung;Max Shapiro

  • Determinants of Viral Clearance and Persistence during Acute Hepatitis C Virus Infection

    Robert Thimme;David Oldach;Kyong Mi Chang;Kyong Mi Chang;Carola Steiger

  • Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes

    Luca G Guidotti;Luca G Guidotti;Tetsuya Ishikawa;Monte V Hobbs;Brent Matzke

  • Noncytolytic control of viral infections by the innate and adaptive immune response.

    Luca G. Guidotti;Francis V. Chisari

  • CD8+ T Cells Mediate Viral Clearance and Disease Pathogenesis during Acute Hepatitis B Virus Infection

    Robert Thimme;Stefan Wieland;Carola Steiger;John Ghrayeb

  • Interferon modulation of cellular microRNAs as an antiviral mechanism.

    Irene M. Pedersen;Guofeng Cheng;Stefan Wieland;Stefano Volinia

  • Genomic analysis of the host response to hepatitis C virus infection.

    Andrew I. Su;John P. Pezacki;Lisa Wodicka;Amy D. Brideau

  • The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes.

    A. Sette;A. Vitiello;B. Reherman;P. Fowler

  • The hepatitis B virus persists for decades after patients' recovery from acute viral hepatitis despite active maintenance of a cytotoxic T–lymphocyte response

    Barbara Rehermann;Carlo Ferrari;Claudio Pasquinelli;Francis V. Chisari

  • Immunobiology and pathogenesis of viral hepatitis.

    Luca G. Guidotti;Francis V. Chisari

  • Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice

    Francis V. Chisari;Kathleen Klopchin;Takashi Moriyama;Claudio Pasquinelli

  • High-level hepatitis B virus replication in transgenic mice.

    L G Guidotti;B Matzke;H Schaller;F V Chisari

  • Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease

    Robert Thimme;Jens Bukh;Hans Christian Spangenberg;Stefan Wieland

  • Natural Killer T Cell Activation Inhibits Hepatitis B Virus Replication in Vivo

    Kazuhiro Kakimi;Luca G. Guidotti;Yasuhiko Koezuka;Francis V. Chisari

  • Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids

    Sharookh B. Kapadia;Francis V. Chisari

  • Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells

    Antonio Bertoletti;Alessandro Sette;Francis V. Chisari;Amalia Penna

  • Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge

    Mansun Law;Toshiaki Maruyama;Jamie Lewis;Erick Giang

  • Interference of hepatitis C virus RNA replication by short interfering RNAs

    Sharookh B. Kapadia;Amy Brideau-Andersen;Francis V. Chisari

Frequent Co-Authors

Luca G. Guidotti
Luca G. Guidotti Vita-Salute San Raffaele University
Stefan Wieland
Stefan Wieland University Hospital of Basel
Carlo Ferrari
Carlo Ferrari University of Parma
Alessandro Sette
Alessandro Sette La Jolla Institute For Allergy & Immunology
David R. Milich
David R. Milich Scripps Health
Robert H. Purcell
Robert H. Purcell National Institute of Allergy and Infectious Diseases
Kyong-Mi Chang
Kyong-Mi Chang University of Pennsylvania
Robert Thimme
Robert Thimme University of Freiburg
Kazuhiro Kakimi
Kazuhiro Kakimi Kindai University
Antonio Bertoletti
Antonio Bertoletti Duke NUS Graduate Medical School

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