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2025
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Immunology
USA
2026

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Best Scientists

D-Index
172
Citations
102802
World Ranking
813
National Ranking
489

Immunology

D-Index
172
Citations
102431
World Ranking
51
National Ranking
38

Medicine

D-Index
172
Citations
102363
World Ranking
496
National Ranking
296

Research.com Recognitions

  • 2026 - Research.com Immunology in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Immunology in United States Leader Award
  • 1999 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1998 - King Faisal Prize
  • 1988 - Member of the National Academy of Sciences
  • 1980 - Oswald Avery Award, Infectious Diseases Society of America
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Robert H. Purcell is affiliated with the National Institute of Allergy and Infectious Diseases in the United States. Their primary field of research is Medicine, with a focus on Hepatology, Epidemiology, Molecular Biology, Critical Care and Intensive Care Medicine, and Physiology.

The scientist's work spans several key topics, including:

  • Hepatitis C virus research
  • Hepatitis B Virus Studies
  • Hepatitis Viruses Studies and Epidemiology
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Peroxisome Proliferator-Activated Receptors
  • Adipose Tissue and Metabolism
  • Eicosanoids and Hypertension Pharmacology

Notable recent publications include:

  • "Context-dependent regulation of endothelial cell metabolism: differential effects of the PPARβ/δ agonist GW0742 and VEGF-A," 2020, Scientific Reports
  • "Preclinical models for studying immune responses to traumatic injury," 2020, Immunology
  • "Distinct Cytokine Profiles Correlate with Disease Severity and Outcome in Longitudinal Studies of Acute Hepatitis B Virus and Hepatitis D Virus Infection in Chimpanzees," 2020, mBio
  • "Distinct disease features in chimpanzees infected with a precore HBV mutant associated with acute liver failure in humans," 2020, PLoS Pathogens
  • "Effect of parachute delivery on red blood cell (RBC) and plasma quality measures of blood for transfusion," 2021, Transfusion

Frequent co-authors in this body of work include:

  • Patrizia Farci
  • Ronald E. Engle
  • Zhaochun Chen
  • Jessica Katy Skelton
  • Emily J. Danoff

Published work often appears in the following venues:

  • PLoS Pathogens
  • Scientific Reports
  • Immunology
  • mBio
  • Transfusion

Robert H. Purcell has received several awards and honors, including:

  • Fellow of the American Association for the Advancement of Science (AAAS), 1999
  • King Faisal Prize, 1998
  • Member of the National Academy of Sciences, 1988
  • Oswald Avery Award, Infectious Diseases Society of America, 1980
  • Member of the Association of American Physicians

Best Publications

  • An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis

    G. Kuo;Q.-L. Choo;H.J. Alter;G.L. Gitnick

  • Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis

    Harvey J. Alter;Robert H. Purcell;James W. Shih;Jacqueline C. Melpolder

  • An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis.

    Unknown

  • Viral Clearance Without Destruction of Infected Cells During Acute HBV Infection

    Luca G. Guidotti;Rosemary Rochford;Josan Chung;Max Shapiro

  • A novel virus in swine is closely related to the human hepatitis E virus

    Xiang-Jin Meng;Robert H. Purcell;Patrick G. Halbur;James R. Lehman

  • Interrelationship of blood transfusion, non‐A, non‐B hepatitis and hepatocellular carcinoma: Analysis by detection of antibody to hepatitis C virus

    Kendo Kiyosawa;Takeshi Sodeyama;Eiji Tanaka;Yukio Gibo

  • CD8+ T Cells Mediate Viral Clearance and Disease Pathogenesis during Acute Hepatitis B Virus Infection

    Robert Thimme;Stefan Wieland;Carola Steiger;John Ghrayeb

  • The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies.

    Patrizia Farci;Atsushi Shimoda;Alessandra Coiana;Giacomo Diaz

  • Genetic Heterogeneity of Hepatitis C Virus: Quasispecies and Genotypes

    Jens Bukh;Roger H. Miller;Robert H. Purcell

  • Hepatitis E virus.

    Suzanne U. Emerson;Robert H. Purcell

  • Genomic analysis of the host response to hepatitis C virus infection.

    Andrew I. Su;John P. Pezacki;Lisa Wodicka;Amy D. Brideau

  • Hepatitis A: Detection by Immune Electron Microscopy of a Viruslike Antigen Associated with Acute Illness

    Stephen M. Feinstone;Albert Z. Kapikian;Robert H. Purcell

  • DNA polymerase associated with human hepatitis B antigen.

    Paul M. Kaplan;Paul M. Kaplan;Paul M. Kaplan;Richard L. Greenman;Richard L. Greenman;Richard L. Greenman;John L. Gerin;John L. Gerin;John L. Gerin;Robert H. Purcell;Robert H. Purcell;Robert H. Purcell

  • An African primate lentivirus (SIVsm) closely related to HIV-2

    Vanessa M. Hirsch;Robert A. Olmsted;Michael Murphey-Corb;Robert H. Purcell

  • Lack of protective immunity against reinfection with hepatitis C virus

    Patrizia Farci;Harvey J. Alter;Sugantha Govindarajan;Doris C. Wong

  • Hepatitis C virus shares amino acid sequence similarity with pestiviruses and flaviviruses as well as members of two plant virus supergroups

    Roger H. Miller;Robert H. Purcell

  • Hepatitis E: an emerging awareness of an old disease.

    R.H. Purcell;S.U. Emerson

  • Nucleotide sequence and mutation rate of the H strain of hepatitis C virus.

    Norio Ogata;Harvey J. Alter;Roger H. Miller;Robert H. Purcell

  • Prevention of Hepatitis C Virus Infection in Chimpanzees by Hyperimmune Serum against the Hypervariable Region 1 of the Envelope 2 Protein

    Patrizia Farci;Atsushi Shimoda;Doris Wong;Teresa Cabezon

  • Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease

    Robert Thimme;Jens Bukh;Hans Christian Spangenberg;Stefan Wieland

  • Transfusion-Associated Hepatitis Not Due to Viral Hepatitis Type A or B

    Stephen M. Feinstone;Albert Z. Kapikian;Robert H. Purcell;Harvey J. Alter

  • National Institutes of Health Consensus Development Conference panel statement: Management of hepatitis C

    D. W. Powell;B. Z. Abramson;J. A. Balint;S. Belle

Frequent Co-Authors

Suzanne U. Emerson
Suzanne U. Emerson National Institute of Allergy and Infectious Diseases
Jens Bukh
Jens Bukh University of Copenhagen
Ronald E. Engle
Ronald E. Engle National Institute of Allergy and Infectious Diseases
John L. Gerin
John L. Gerin Georgetown University Medical Center
Jules L. Dienstag
Jules L. Dienstag Harvard University
Harvey J. Alter
Harvey J. Alter National Institutes of Health
Sugantha Govindarajan
Sugantha Govindarajan University of Southern California
Patrizia Farci
Patrizia Farci National Institutes of Health
Hans Popper
Hans Popper Icahn School of Medicine at Mount Sinai
Robert M. Chanock
Robert M. Chanock National Institutes of Health

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