Masaharu Takahashi

Overview

Best Publications

• Sporadic acute or fulminant hepatitis E in Hokkaido, Japan, may be food-borne, as suggested by the presence of hepatitis E virus in pig liver as food

  Yasuyuki Yazaki;Hitoshi Mizuo;Masaharu Takahashi;Tsutomu Nishizawa

  841
  Citations

• Polyphyletic Strains of Hepatitis E Virus Are Responsible for Sporadic Cases of Acute Hepatitis in Japan

  Hitoshi Mizuo;Kazuyuki Suzuki;Yasuhiro Takikawa;Yoshiki Sugai

  402
  Citations

• Marked genomic heterogeneity and frequent mixed infection of TT virus demonstrated by PCR with primers from coding and noncoding regions.

  Hiroaki Okamoto;Masaharu Takahashi;Tsutomu Nishizawa;Masato Ukita

  363
  Citations

• Swine hepatitis E virus strains in Japan form four phylogenetic clusters comparable with those of Japanese isolates of human hepatitis E virus.

  Masaharu Takahashi;Tsutomu Nishizawa;Haruko Miyajima;Yuhko Gotanda

  351
  Citations

• Hepatitis E Virus (HEV) Strains in Serum Samples Can Replicate Efficiently in Cultured Cells Despite the Coexistence of HEV Antibodies: Characterization of HEV Virions in Blood Circulation

  Masaharu Takahashi;Toshinori Tanaka;Hideyuki Takahashi;Yu Hoshino

  351
  Citations

• Development and evaluation of an efficient cell-culture system for Hepatitis E virus.

  Toshinori Tanaka;Masaharu Takahashi;Eiji Kusano;Hiroaki Okamoto

  342
  Citations

• ORF3 protein of hepatitis E virus is essential for virion release from infected cells.

  Kentaro Yamada;Masaharu Takahashi;Yu Hoshino;Hideyuki Takahashi

  306
  Citations

• Genomic characterization of TT viruses (TTVs) in pigs, cats and dogs and their relatedness with species-specific TTVs in primates and tupaias.

  Hiroaki Okamoto;Masaharu Takahashi;Tsutomu Nishizawa;Akio Tawara

  304
  Citations

• Analysis of the full-length genome of a hepatitis E virus isolate obtained from a wild boar in Japan that is classifiable into a novel genotype.

  Masaharu Takahashi;Tsutomu Nishizawa;Hiroyuki Sato;Yukihiro Sato

  304
  Citations

• Analysis of the complete genome of indigenous swine hepatitis E virus isolated in Japan.

  Hiroaki Okamoto;Masaharu Takahashi;Tsutomu Nishizawa;Katsuhiko Fukai

  296
  Citations

• Possible risk factors for the transmission of hepatitis E virus and for the severe form of hepatitis E acquired locally in Hokkaido, Japan

  Hitoshi Mizuo;Yasuyuki Yazaki;Kenji Sugawara;Fumio Tsuda

  291
  Citations

• Simultaneous Detection of Immunoglobulin A (IgA) and IgM Antibodies against Hepatitis E Virus (HEV) Is Highly Specific for Diagnosis of Acute HEV Infection

  Masaharu Takahashi;Shigeyuki Kusakai;Hitoshi Mizuo;Kazuyuki Suzuki

  265
  Citations

• Hepatitis E virus egress depends on the exosomal pathway, with secretory exosomes derived from multivesicular bodies

  Shigeo Nagashima;Suljid Jirintai;Masaharu Takahashi;Tominari Kobayashi

  264
  Citations

• Prevalence of Hepatitis E Virus (HEV) Infection in Wild Boars and Deer and Genetic Identification of a Genotype 3 HEV from a Boar in Japan

  Hideto Sonoda;Masahiko Abe;Takeshi Sugimoto;Yukihiro Sato

  248
  Citations

• Characterization of the Quasi-Enveloped Hepatitis E Virus Particles Released by the Cellular Exosomal Pathway.

  Shigeo Nagashima;Masaharu Takahashi;Tominari Kobayashi;Tanggis

  247
  Citations

• Characterization of Japanese swine and human hepatitis E virus isolates of genotype IV with 99 % identity over the entire genome.

  Tsutomu Nishizawa;Masaharu Takahashi;Hitoshi Mizuo;Haruko Miyajima

  240
  Citations

• Analysis of the entire genomes of thirteen TT virus variants classifiable into the fourth and fifth genetic groups, isolated from viremic infants.

  Y. H. Peng;T. Nishizawa;M. Takahashi;T. Ishikawa

  238
  Citations

• Prevalence of hepatitis E virus infection among hemodialysis patients in Japan: evidence for infection with a genotype 3 HEV by blood transfusion.

  Takehiro Mitsui;Yukie Tsukamoto;Chikao Yamazaki;Kazuo Masuko

  211
  Citations

• Monoclonal antibodies raised against the ORF3 protein of hepatitis E virus (HEV) can capture HEV particles in culture supernatant and serum but not those in feces.

  Masaharu Takahashi;Kentaro Yamada;Yu Hoshino;Hideyuki Takahashi

  208
  Citations

• A PSAP motif in the ORF3 protein of hepatitis E virus is necessary for virion release from infected cells.

  Shigeo Nagashima;Masaharu Takahashi;Jirintai;Toshinori Tanaka

  199
  Citations