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Medicine

D-Index
89
Citations
31776
World Ranking
12608
National Ranking
6447

Overview

Irwin Lucki is affiliated with the University of Pennsylvania in the United States and has contributed extensively to the fields of neuroscience and medicine. Their research primarily spans pharmacology, cellular and molecular neuroscience, molecular biology, physiology, and biological psychiatry.

The main research topics addressed in their work include:

  • Treatment of Major Depression
  • Neuropeptides and Animal Physiology
  • Pain Mechanisms and Treatments
  • Tryptophan and Brain Disorders
  • Stress Responses and Cortisol
  • Pharmacological Receptor Mechanisms and Effects
  • Receptor Mechanisms and Signaling

Lucki has published papers in a range of scientific journals, with frequent contributions in:

  • Psychopharmacology
  • Neuropharmacology
  • Journal of Pharmacology and Experimental Therapeutics
  • The FASEB Journal
  • The Annual Review of Pharmacology and Toxicology

Recent selected publications include:

  • Kappa Opioid Receptor Antagonists as Potential Therapeutics for Stress-Related Disorders (2020) in The Annual Review of Pharmacology and Toxicology
  • Novel Targets to Treat Depression: Opioid-Based Therapeutics (2020) in Harvard Review of Psychiatry
  • The kappa opioid receptor antagonist aticaprant reverses behavioral effects from unpredictable chronic mild stress in male mice (2020) in Psychopharmacology
  • Mediation of the behavioral effects of ketamine and (2R,6R)-hydroxynorketamine in mice by kappa opioid receptors (2022) in Psychopharmacology
  • Vendor differences in anxiety-like behaviors in female and male Sprague Dawley rats (2020) in Physiology & Behavior

Frequent co-authors collaborating with Lucki include:

  • Caroline A. Browne
  • Hildegard A. Wulf
  • Moriah L. Jacobson
  • Mumeko C. Tsuda
  • Jonathan G. Yost

Best Publications

  • Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants.

    Michael J. Detke;Michael Rickels;Irwin Lucki

  • Assessing antidepressant activity in rodents: recent developments and future needs

    John F. Cryan;Athina Markou;Irwin Lucki

  • The spectrum of behaviors influenced by serotonin

    Irwin Lucki

  • Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test.

    John F. Cryan;Rita J. Valentino;Irwin Lucki

  • The forced swimming test as a model for core and component behavioral effects of antidepressant drugs.

    I Lucki

  • Sensitivity to the effects of pharmacologically selective antidepressants in different strains of mice.

    Irwin Lucki;Ashutosh Dalvi;Arthur J. Mayorga

  • 5-HT1A Receptor Function in Major Depressive Disorder

    Jonathan Savitz;Irwin Lucki;Wayne C. Drevets

  • Adult hippocampal neurogenesis: Regulation, functional implications, and contribution to disease pathology

    Darrick T. Balu;Irwin Lucki

  • Detection of serotonergic and noradrenergic antidepressants in the rat forced swimming test: the effects of water depth

    Michael J. Detke;Irwin Lucki

  • Serotonergic mediation of the effects of fluoxetine, but not desipramine, in the rat forced swimming test

    Michelle E. Page;Michael J. Detke;Ashutosh Dalvi;Lynn G. Kirby

  • cAMP Response Element-Binding Protein Is Essential for the Upregulation of Brain-Derived Neurotrophic Factor Transcription, But Not the Behavioral or Endocrine Responses to Antidepressant Drugs

    Alana C. Conti;John F. Cryan;Ashutosh Dalvi;Irwin Lucki

  • Antidepressant-like behavioral effects mediated by 5-Hydroxytryptamine(2C) receptors.

    John F. Cryan;Irwin Lucki

  • Differential behavioral effects of the antidepressants reboxetine, fluoxetine, and moclobemide in a modified forced swim test following chronic treatment.

    John F. Cryan;Michelle E. Page;Michelle E. Page;Irwin Lucki

  • Acute and chronic antidepressant drug treatment in the rat forced swimming test model of depression.

    Michael J. Detke;Jennie Johnson;Irwin Lucki

  • Central administration of IGF-I and BDNF leads to long-lasting antidepressant-like effects.

    Brian A. Hoshaw;Jessica E. Malberg;Irwin Lucki

  • Effects of acute and repeated administration of antidepressant drugs on extracellular levels of 5-hydroxytryptamine measured in vivo.

    D S Kreiss;I Lucki

  • Strain Differences in the Behavioral Effects of Antidepressant Drugs in the Rat Forced Swimming Test

    Carolina López-Rubalcava;Irwin Lucki

  • Differential actions of serotonin antagonists on two behavioral models of serotonin receptor activation in the rat.

    I. Lucki;M. S. Nobler;Alan Frazer

  • Antidepressant behavioral effects by dual inhibition of monoamine reuptake in the rat forced swimming test

    J P Rénéric;I Lucki

  • Strain differences in the behavioral effects of antidepressant drugs in the rat forced swimming test

    C L pez-Rubalcava;PA Rittenhouse;I Lucki

Frequent Co-Authors

Rita J. Valentino
Rita J. Valentino National Institute on Drug Abuse
Alan Frazer
Alan Frazer The University of Texas Health Science Center at San Antonio
John F. Cryan
John F. Cryan University College Cork
Karl Rickels
Karl Rickels University of Pennsylvania
Julie A. Blendy
Julie A. Blendy University of Pennsylvania
Hank F. Kung
Hank F. Kung University of Pennsylvania
Georgia E. Hodes
Georgia E. Hodes Virginia Tech
Jay D. Amsterdam
Jay D. Amsterdam University of Pennsylvania
Gregg D. Stanwood
Gregg D. Stanwood Florida State University
Lee E. Schechter
Lee E. Schechter Princeton University

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