World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
139
Citations
76233
World Ranking
204
National Ranking
134

Medicine

D-Index
139
Citations
76229
World Ranking
1751
National Ranking
1000

Overview

René Hen is affiliated with Columbia University in the United States and has contributed extensively to research in the field of neuroscience. Their work primarily focuses on various aspects of neurobiology, including cellular and molecular neuroscience, developmental neuroscience, and cognitive neuroscience.

Their research encompasses key topics such as neuroscience and neuropharmacology research, neurogenesis and neuroplasticity mechanisms, memory and neural mechanisms, stress responses and cortisol, receptor mechanisms and signaling, tryptophan and brain disorders, and neural dynamics and brain function.

René Hen has published numerous articles in prominent scientific venues. Frequent publication platforms include:

  • Biological Psychiatry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • SSRN Electronic Journal
  • Molecular Psychiatry
  • Neuron

The scientist has also collaborated with several researchers multiple times. Frequent co-authors include:

  • Indira Mendez-David
  • Denis J. David
  • Clay Lacefield
  • Wei-li Chang
  • Gergely F. Turi

Among their recent scientific papers are the following:

  • Dysregulation of adult hippocampal neuroplasticity in major depression: pathogenesis and therapeutic implications (2022), published in Molecular Psychiatry
  • A Distributed Neural Code in the Dentate Gyrus and in CA1 (2020), published in Neuron
  • Contextual fear memory retrieval by correlated ensembles of ventral CA1 neurons (2020), published in Nature Communications
  • Single-cell activity and network properties of dorsal raphe nucleus serotonin neurons during emotionally salient behaviors (2022), published in Neuron
  • Adult neurogenesis augmentation attenuates anhedonia and HPA axis dysregulation in a mouse model of chronic stress and depression (2020), published in Psychoneuroendocrinology

Best Publications

  • Requirement of Hippocampal Neurogenesis for the Behavioral Effects of Antidepressants

    Luca Santarelli;Michael Saxe;Cornelius Gross;Alexandre Surget

  • Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation.

    Amar Sahay;Kimberly N. Scobie;Alexis S. Hill;Colin M. O'Carroll

  • An in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus.

    Ana C. Pereira;Dan E. Huddleston;Adam M. Brickman;Alexander A. Sosunov

  • Adult hippocampal neurogenesis in depression.

    Amar Sahay;Rene Hen

  • Human Hippocampal Neurogenesis Persists throughout Aging

    Maura Boldrini;Camille A. Fulmore;Alexandria N. Tartt;Laika R. Simeon

  • Neurogenesis-Dependent and -Independent Effects of Fluoxetine in an Animal Model of Anxiety/Depression

    Denis J. David;Benjamin Adam Samuels;Quentin Rainer;Jing Wen Wang

  • Reversal of Neuropathology and Motor Dysfunction in a Conditional Model of Huntington's Disease

    Ai Yamamoto;José J Lucas;René Hen

  • Enhanced aggressive behavior in mice lacking 5-HT1B receptor

    Frédéric Saudou;Djamel Aït Amara;Andrée Dierich;Marianne LeMeur

  • Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus

    Michael D. Saxe;Fortunato Battaglia;Jing Wen Wang;Gael Malleret

  • Decreased nuclear β‐catenin, tau hyperphosphorylation and neurodegeneration in GSK‐3β conditional transgenic mice

    José Javier Lucas;José Javier Lucas;Félix Hernández;Félix Hernández;Pilar Gómez-Ramos;María A. Morán

  • Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult.

    Cornelius Gross;Xiaoxi Zhuang;Xiaoxi Zhuang;Kimberly Stark;Sylvie Ramboz

  • Early-Life Blockade of the 5-HT Transporter Alters Emotional Behavior in Adult Mice

    Mark S. Ansorge;Mingming Zhou;Alena Lira;René Hen

  • Serotonin receptor 1A knockout: an animal model of anxiety-related disorder.

    Sylvie Ramboz;Ronald Oosting;Djamel Aït Amara;Hank F. Kung

  • Adult hippocampal neurogenesis and cognitive flexibility - linking memory and mood.

    Christoph Anacker;René Hen

  • Lrp5 Controls Bone Formation by Inhibiting Serotonin Synthesis in the Duodenum

    Vijay K. Yadav;Je Hwang Ryu;Nina Suda;Kenji F. Tanaka

  • Hippocampal neurogenesis: regulation by stress and antidepressants.

    Alex Dranovsky;René Hen

  • Antidepressants increase neural progenitor cells in the human hippocampus

    Maura Boldrini;Maura Boldrini;Mark D Underwood;René Hen;Gorazd B Rosoklija;Gorazd B Rosoklija

  • Effects of chronic fluoxetine in animal models of anxiety and depression.

    Stephanie C Dulawa;Kerri A Holick;Brigitta Gundersen;Rene Hen

  • Human Adult Neurogenesis: Evidence and Remaining Questions.

    Gerd Kempermann;Fred H. Gage;Ludwig Aigner;Hongjun Song

  • Individual Differences in Trait Anxiety Predict the Response of the Basolateral Amygdala to Unconsciously Processed Fearful Faces

    Amit Etkin;Kristen C. Klemenhagen;Joshua T. Dudman;Michael T. Rogan

  • The developmental origins of anxiety.

    Cornelius Gross;Rene Hen

Frequent Co-Authors

Alain M. Gardier
Alain M. Gardier University of Paris-Saclay
Kenji F. Tanaka
Kenji F. Tanaka Keio University
Victoria Arango
Victoria Arango Columbia University
Gorazd Rosoklija
Gorazd Rosoklija Columbia University
Amar Sahay
Amar Sahay Harvard University
Jay A. Gingrich
Jay A. Gingrich Columbia University
Catherine Belzung
Catherine Belzung François Rabelais University
Berend Olivier
Berend Olivier Utrecht University
Bruno P. Guiard
Bruno P. Guiard University of Toulouse-Jean Jaurès
Jean-Philippe Guilloux
Jean-Philippe Guilloux University of Paris-Saclay

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