Paul J. Lucassen

Overview

Best Publications

• The stress system in the human brain in depression and neurodegeneration.

  Dick F. Swaab;Ai-Min Bao;Paul J. Lucassen

  1238
  Citations

• Human Adult Neurogenesis: Evidence and Remaining Questions.

  Gerd Kempermann;Fred H. Gage;Ludwig Aigner;Hongjun Song

  819
  Citations

• What causes the hippocampal volume decrease in depression? Are neurogenesis, glial changes and apoptosis implicated?

  Boldizsár Czéh;Paul J. Lucassen

  579
  Citations

• Regulation of adult neurogenesis by stress, sleep disruption, exercise and inflammation: Implications for depression and antidepressant action

  P J Lucassen;P Meerlo;A S Naylor;A S Naylor;A M van Dam

  579
  Citations

• Neuropathology of stress

  Paul J. Lucassen;Jens Pruessner;Nuno Sousa;Osborne F. X. Almeida

  541
  Citations

• The Indispensable Roles of Microglia and Astrocytes during Brain Development

  Kitty Reemst;Stephen C. Noctor;Paul J. Lucassen;Elly M. Hol;Elly M. Hol;Elly M. Hol

  539
  Citations

• Corticotropin-Releasing Hormone mRNA Levels in the Paraventricular Nucleus of Patients With Alzheimer's Disease and Depression

  F. C. Raadsheer;J. J. Van Heerikhuize;P. J. Lucassen;W. J. G. Hoogendijk

  506
  Citations

• Chronic stress: Implications for neuronal morphology, function and neurogenesis.

  Marian Joëls;Henk Karst;Harmen J. Krugers;Paul J. Lucassen

  469
  Citations

• Effects of chronic stress on structure and cell function in rat hippocampus and hypothalamus

  Marian Joëls;Henk Karst;Deborah Alfarez;Vivi M Heine

  444
  Citations

• Hippocampal Apoptosis in Major Depression Is a Minor Event and Absent from Subareas at Risk for Glucocorticoid Overexposure

  Paul J. Lucassen;Marianne B. Müller;Florian Holsboer;Jan Bauer

  425
  Citations

• Severe early life stress hampers spatial learning and neurogenesis, but improves hippocampal synaptic plasticity and emotional learning under high-stress conditions in adulthood

  C.A. Oomen;H. Soeters;N. Audureau;L. Vermunt

  419
  Citations

• Increased proliferation reflects glial and vascular-associated changes, but not neurogenesis in the presenile Alzheimer hippocampus.

  Karin Boekhoorn;Marian Joels;Paul J. Lucassen

  411
  Citations

• Chronic early life stress induced by limited bedding and nesting (LBN) material in rodents: critical considerations of methodology, outcomes and translational potential

  Claire-Dominique Walker;Kevin G. Bath;Marian Joels;Aniko Korosi

  410
  Citations

• Suppressed proliferation and apoptotic changes in the rat dentate gyrus after acute and chronic stress are reversible.

  Vivi M Heine;Suharti Maslam;Jessica Zareno;Marian Joëls

  409
  Citations

• Running throughout middle-age improves memory function, hippocampal neurogenesis, and BDNF levels in female C57BL/6J mice

  Michael W. Marlatt;Michelle C. Potter;Paul J. Lucassen;Henriette van Praag

  372
  Citations

• Alterations of neuroplasticity in depression: the hippocampus and beyond.

  Eberhard Fuchs;Eberhard Fuchs;Boldizsár Czéh;Maarten H.P. Kole;Thomas Michaelis

  372
  Citations

• Chronic early life stress alters developmental and adult neurogenesis and impairs cognitive function in mice

  Eva F.G. Naninck;Lianne Hoeijmakers;Nefeli Kakava-Georgiadou;Astrid Meesters

  336
  Citations

• Multidrug resistance P-glycoprotein hampers the access of cortisol but not of corticosterone to mouse and human brain.

  A. M. Karssen;O. C. Meijer;I. C. J. van der Sandt;P. J. Lucassen

  335
  Citations

• Prominent decline of newborn cell proliferation, differentiation, and apoptosis in the aging dentate gyrus, in absence of an age-related hypothalamus-pituitary-adrenal axis activation

  Vivi M Heine;Suharti Maslam;Marian Joëls;Paul J Lucassen

  333
  Citations

• Neither major depression nor glucocorticoid treatment affects the cellular integrity of the human hippocampus

  Marianne B. Müller;Paul J. Lucassen;Paul J. Lucassen;Alexander Yassouridis;Witte J. G. Hoogendijk

  324
  Citations