World's Best Scientists 2026 revealed!
Ralf Bartenschlager

Ralf Bartenschlager

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Medicine
Germany
2026
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Microbiology
Germany
2026

D-Index & Metrics

Microbiology

D-Index
141
Citations
70479
World Ranking
52
National Ranking
1

Medicine

D-Index
141
Citations
70625
World Ranking
1635
National Ranking
82

Research.com Recognitions

  • 2026 - Research.com Medicine in Germany Leader Award
  • 2026 - Research.com Microbiology in Germany Leader Award
  • 2025 - Research.com Microbiology in Germany Leader Award
  • 2023 - Research.com Medicine in Germany Leader Award
  • 2023 - Research.com Microbiology in Germany Leader Award
  • 2022 - Research.com Microbiology in Germany Leader Award
  • 2019 - Prince Mahidol Award
  • 2015 - Robert Koch Prize
  • 2013 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Microbiology and Immunology
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Ralf Bartenschlager is affiliated with Heidelberg University in Germany and has contributed extensively to research in the field of medicine, with a particular focus on infectious diseases. Their academic output encompasses a wide range of topics including viral infections, immunology, and epidemiology.

Their main fields of study include:

  • Infectious Diseases
  • Molecular Biology
  • Epidemiology
  • Immunology
  • Hepatology

The primary research topics covered in their work are:

  • SARS-CoV-2 and COVID-19 Research
  • Hepatitis C virus research
  • Mosquito-borne diseases and control
  • COVID-19 Clinical Research Studies
  • Viral Infections and Vectors
  • Interferon and immune responses
  • Hepatitis B Virus Studies

Frequent publication venues for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Journal of Hepatology
  • Journal of Virology
  • PLoS Pathogens

Among recent papers, notable publications are:

  • Structures and distributions of SARS-CoV-2 spike proteins on intact virions (2020) in Nature
  • SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography (2020) in Nature Communications
  • Integrative Imaging Reveals SARS-CoV-2-Induced Reshaping of Subcellular Morphologies (2020) in Cell Host & Microbe
  • SARS-CoV-2 infection induces a pro-inflammatory cytokine response through cGAS-STING and NF-κB (2022) in Communications Biology
  • A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction (2021) in Nature

Frequent co-authors in their research collaborations include:

  • Paul Schnitzler
  • Mirko Cortese
  • Berati Cerikan
  • Christopher J. Neufeldt
  • Heeyoung Kim

Their contributions have been recognized through awards such as the Prince Mahidol Award in 2019 and the Robert Koch Prize in 2015. They are also a member of the German National Academy of Sciences Leopoldina and have affiliation with the European Molecular Biology Organization (EMBO).

Best Publications

  • Replication of Subgenomic Hepatitis C Virus RNAs in a Hepatoma Cell Line

    V. Lohmann;F. Körner;J.-O. Koch;U. Herian

  • Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

    Takaji Wakita;Thomas Pietschmann;Takanobu Kato;Takanobu Kato;Tomoko Date

  • Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

    Etienne Meylan;Joseph Curran;Kay Hofmann;Darius Moradpour

  • The lipid droplet is an important organelle for hepatitis C virus production.

    Yusuke Miyanari;Kimie Atsuzawa;Nobuteru Usuda;Koichi Watashi

  • Composition and three-dimensional architecture of the dengue virus replication and assembly sites.

    Sonja Welsch;Sven Miller;Ines Romero-Brey;Andreas Merz

  • Structures and distributions of SARS-CoV-2 spike proteins on intact virions.

    Zunlong Ke;Joaquin Oton;Kun Qu;Mirko Cortese

  • Replication of hepatitis C virus.

    Ralf Bartenschlager;Volker Lohmann

  • Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras.

    Thomas Pietschmann;Artur Kaul;George Koutsoudakis;Anna Shavinskaya

  • Identification of the Hepatitis C Virus RNA Replication Complex in Huh-7 Cells Harboring Subgenomic Replicons

    Rainer Gosert;Denise Egger;Volker Lohmann;Ralf Bartenschlager

  • Host-directed therapies for bacterial and viral infections

    Stefan H. E. Kaufmann;Anca Dorhoi;Richard S. Hotchkiss;Ralf Bartenschlager

  • SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography.

    Steffen Klein;Mirko Cortese;Sophie L. Winter;Moritz Wachsmuth-Melm

  • Biochemical properties of hepatitis C virus NS5B RNA-dependent RNA polymerase and identification of amino acid sequence motifs essential for enzymatic activity.

    V Lohmann;F Körner;U Herian;R Bartenschlager

  • Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations.

    Nicole Krieger;Volker Lohmann;Ralf Bartenschlager

  • Nonstructural protein 3 of the hepatitis C virus encodes a serine-type proteinase required for cleavage at the NS3/4 and NS4/5 junctions.

    R Bartenschlager;L Ahlborn-Laake;J Mous;H Jacobsen

  • Essential role of domain III of nonstructural protein 5A for hepatitis C virus infectious particle assembly.

    Nicole Appel;Margarita Zayas;Sven Miller;Jacomine Krijnse-Locker

  • Mutations in Hepatitis C Virus RNAs Conferring Cell Culture Adaptation

    Volker Lohmann;Frank Körner;Aneta Dobierzewska;Ralf Bartenschlager

  • The non-structural protein 4A of dengue virus is an integral membrane protein inducing membrane alterations in a 2K-regulated manner.

    Sven Miller;Stefan Kastner;Jacomine Krijnse-Locker;Sandra Bühler

  • Three-Dimensional Architecture and Biogenesis of Membrane Structures Associated with Hepatitis C Virus Replication

    Inés Romero-Brey;Andreas Merz;Abhilash Chiramel;Ji-Young Lee

  • Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment

    Simon Reiss;Ilka Rebhan;Perdita Backes;Ines Romero-Brey

  • Assembly of infectious hepatitis C virus particles

    Ralf Bartenschlager;Francois Penin;Francois Penin;Volker Lohmann;Patrice André

  • Replication of the hepatitis C virus

    Ralf Bartenschlager;Volker Lohmann

Frequent Co-Authors

Volker Lohmann
Volker Lohmann Heidelberg University
Thomas Pietschmann
Thomas Pietschmann Hannover Medical School
François Penin
François Penin Claude Bernard University Lyon 1
Karl Rohr
Karl Rohr Heidelberg University
David L. Paul
David L. Paul Harvard University
Mirjam B. Zeisel
Mirjam B. Zeisel University of Strasbourg
Darius Moradpour
Darius Moradpour University of Lausanne
François-Loïc Cosset
François-Loïc Cosset Claude Bernard University Lyon 1
Dieter Häussinger
Dieter Häussinger Heinrich Heine University Düsseldorf
Thomas F. Baumert
Thomas F. Baumert University of Strasbourg

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