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Thomas Pietschmann

Thomas Pietschmann

D-Index & Metrics

Microbiology

D-Index
72
Citations
27124
World Ranking
1711
National Ranking
126

Overview

Thomas Pietschmann is a researcher affiliated with Hannover Medical School in Germany. Their academic focus lies primarily in medicine, with a significant emphasis on hepatology and epidemiology. Pietschmann's work spans several subfields, including rheumatology, hematology, and radiology, nuclear medicine, and imaging.

The scientist's research covers various topics, notably investigations into hepatitis viruses and liver diseases. Key thematic areas include hepatitis C virus research, hepatitis B virus studies, and epidemiological studies related to hepatitis viruses. Additional topics addressed in their publications encompass systemic lupus erythematosus research, liver disease diagnosis and treatment, liver disease and transplantation, and blood groups and transfusion.

Recent publications by Thomas Pietschmann feature studies published between 2023 and 2025. These include:

  • Challenge Inoculum for Hepatitis C Virus Controlled Human Infection Model, 2023, Clinical Infectious Diseases
  • Joint statement in support of hepatitis C human challenge studies, 2023, The Lancet. Gastroenterology & Hepatology
  • The triglyceride-synthesizing enzyme diacylglycerol acyltransferase 2 modulates the formation of the hepatitis C virus replication organelle, 2024, PLoS Pathogens
  • Adapted hepatitis C virus clone infects innate immunity-deficient mouse hepatocytes with minimal human HCV entry factors, 2025, JHEP Reports
  • Extrahepatic Replication and Genomic Signatures of the Hepatitis E Virus in the Kidney, 2025, Liver International

Frequent coauthors in Pietschmann's research include:

  • T. Jake Liang
  • Charles M. Rice
  • Lucas Hüffner
  • Heiner Wedemeyer
  • Patrick Behrendt

The scientist's work appears regularly in a number of publication venues such as Zeitschrift für Gastroenterologie, JHEP Reports, bioRxiv (Cold Spring Harbor Laboratory), Clinical Infectious Diseases, and The Lancet. Gastroenterology & Hepatology.

Best Publications

  • Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

    Takaji Wakita;Thomas Pietschmann;Takanobu Kato;Takanobu Kato;Tomoko Date

  • Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras.

    Thomas Pietschmann;Artur Kaul;George Koutsoudakis;Anna Shavinskaya

  • EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy

    Joachim Lupberger;Mirjam B Zeisel;Mirjam B Zeisel;Fei Xiao;Fei Xiao;Christine Thumann;Christine Thumann

  • The HCV Life Cycle: In vitro Tissue Culture Systems and Therapeutic Targets

    Gisa Gerold;Thomas Pietschmann

  • Anti-infective properties of epigallocatechin-3-gallate (EGCG), a component of green tea.

    J Steinmann;J Buer;T Pietschmann;E Steinmann

  • Characterization of the Early Steps of Hepatitis C Virus Infection by Using Luciferase Reporter Viruses

    George Koutsoudakis;Artur Kaul;Eike Steinmann;Stephanie Kallis

  • Hepatitis C Virus p7 Protein Is Crucial for Assembly and Release of Infectious Virions

    Eike Steinmann;Francois Penin;Stephanie Kallis;Arvind H Patel

  • Persistent and Transient Replication of Full-Length Hepatitis C Virus Genomes in Cell Culture

    Thomas Pietschmann;Volker Lohmann;Artur Kaul;Nicole Krieger

  • Characterization of Cell Lines Carrying Self-Replicating Hepatitis C Virus RNAs

    Thomas Pietschmann;Volker Lohmann;Gabriel Rutter;Katharina Kurpanek

  • A Lymphotoxin-Driven Pathway to Hepatocellular Carcinoma

    Johannes Haybaeck;Nicolas Zeller;Monika Julia Wolf;Achim Weber

  • Novel insights into hepatitis C virus replication and persistence.

    Ralf Bartenschlager;Michael Frese;Thomas Pietschmann

  • Mutational Analysis of Hepatitis C Virus Nonstructural Protein 5A: Potential Role of Differential Phosphorylation in RNA Replication and Identification of a Genetically Flexible Domain

    Nicole Appel;Thomas Pietschmann;Ralf Bartenschlager

  • Scavenger receptor class B type I is a key host factor for hepatitis C virus infection required for an entry step closely linked to CD81

    Mirjam B. Zeisel;George Koutsoudakis;Eva K. Schnober;Anita Haberstroh;Anita Haberstroh

  • Mutations that permit efficient replication of hepatitis C virus RNA in Huh-7 cells prevent productive replication in chimpanzees

    Jens Bukh;Thomas Pietschmann;Volker Lohmann;Nicole Krieger

  • The green tea polyphenol, epigallocatechin-3-gallate, inhibits hepatitis C virus entry.

    Sandra Ciesek;Thomas von Hahn;Che C. Colpitts;Luis M. Schang

  • The level of CD81 cell surface expression is a key determinant for productive entry of hepatitis C virus into host cells.

    George Koutsoudakis;Eva Herrmann;Stephanie Kallis;Ralf Bartenschlager

  • High density lipoprotein inhibits hepatitis C virus-neutralizing antibodies by stimulating cell entry via activation of the scavenger receptor BI.

    Marlène Dreux;Marlène Dreux;Thomas Pietschmann;Christelle Granier;Christelle Granier;Cécile Voisset

  • Analysis of Hepatitis C Virus Superinfection Exclusion by Using Novel Fluorochrome Gene-Tagged Viral Genomes

    Torsten Schaller;Nicole Appel;George Koutsoudakis;Stephanie Kallis

  • Interferon-α inhibits hepatitis C virus subgenomic RNA replication by an MxA-independent pathway

    Michael Frese;Thomas Pietschmann;Darius Moradpour;Otto Haller

  • Hepatitis C Virus Hypervariable Region 1 Modulates Receptor Interactions, Conceals the CD81 Binding Site, and Protects Conserved Neutralizing Epitopes

    Dorothea Bankwitz;Eike Steinmann;Julia Bitzegeio;Sandra Ciesek

Frequent Co-Authors

Eike Steinmann
Eike Steinmann Ruhr University Bochum
Ralf Bartenschlager
Ralf Bartenschlager Heidelberg University
Sandra Ciesek
Sandra Ciesek Goethe University Frankfurt
Michael P. Manns
Michael P. Manns Hannover Medical School
Thomas F. Baumert
Thomas F. Baumert University of Strasbourg
Heiner Wedemeyer
Heiner Wedemeyer Hannover Medical School
Philip Meuleman
Philip Meuleman Ghent University
Volker Thiel
Volker Thiel University of Bern
Mirjam B. Zeisel
Mirjam B. Zeisel University of Strasbourg
François-Loïc Cosset
François-Loïc Cosset Claude Bernard University Lyon 1

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