World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
16097
World Ranking
14202
National Ranking
5988

Overview

Jean Gautier is affiliated with Columbia University in the United States and has contributed extensively to research in biochemistry, genetics, and molecular biology. Their work primarily focuses on molecular biology, with additional contributions to plant science, materials chemistry, immunology, and oncology.

The scientist's main research topics include:

  • DNA repair mechanisms
  • Genomics and chromatin dynamics
  • Chromosomal and genetic variations
  • CRISPR and genetic engineering
  • DNA and nucleic acid chemistry
  • Epigenetics and DNA methylation
  • Cancer-related molecular pathways

Jean Gautier's recent publications include the following notable papers:

  • "Multiscale reorganization of the genome following DNA damage facilitates chromosome translocations via nuclear actin polymerization," 2022, Nature Structural & Molecular Biology
  • "Dual-Color Plasmonic Nanosensor for Radiation Dosimetry," 2020, ACS Applied Materials & Interfaces
  • "Inhibition of DNA replication initiation by silver nanoclusters," 2021, Nucleic Acids Research
  • "Mechanisms of insertions at a DNA double-strand break," 2023, Molecular Cell
  • "Functional mapping of PHF6 complexes in chromatin remodeling, replication dynamics, and DNA repair," 2022, Blood

Frequent co-authors collaborating with Jean Gautier include:

  • Raúl Rabadán
  • Shan Zha
  • Jennifer Zagelbaum
  • Junfei Zhao
  • Allana Schooley

The scientist's publications have appeared regularly in these venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Structural & Molecular Biology
  • Proceedings of the National Academy of Sciences
  • DNA Repair
  • The Journal of Cell Biology

Jean Gautier's research explores the dynamics of DNA repair and chromatin architecture, emphasizing mechanisms underlying genome maintenance and stability. Their work includes studying DNA double-strand breaks, replication initiation control, and chromatin remodeling complexes involved in repair processes.

Through collaborations and multidisciplinary approaches, Jean Gautier bridges molecular biology with materials chemistry and cancer-related molecular pathways, contributing to a broader understanding of genome integrity and cellular responses to DNA damage.

Best Publications

  • Double-Strand Break End Resection and Repair Pathway Choice

    Lorraine S. Symington;Jean Gautier

  • Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+.

    Jean Gautier;Chris Norbury;Manfred Lohka;Paul Nurse

  • cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2

    Jean Gautier;Mark J. Solomon;Robert N. Booher;J.Fernando Bazan

  • Cyclin is a component of maturation-promoting factor from Xenopus

    Jean Gautier;Jeremy Minshull;Manfred Lohka;Michael Glotzer

  • Non-transcriptional control of DNA replication by c-Myc

    David Dominguez-Sola;Carol Y. Ying;Carla Grandori;Carla Grandori;Luca Ruggiero

  • ATR and ATM regulate the timing of DNA replication origin firing.

    David Shechter;David Shechter;Vincenzo Costanzo;Jean Gautier

  • An ATR- and Cdc7-Dependent DNA Damage Checkpoint that Inhibits Initiation of DNA Replication

    Vincenzo Costanzo;David Shechter;Patrick J Lupardus;Karlene A Cimprich

  • A forward chemical genetic screen reveals an inhibitor of the Mre11-Rad50-Nbs1 complex

    Aude Dupré;Louise Boyer-Chatenet;Louise Boyer-Chatenet;Rose M Sattler;Ami P Modi

  • A human B‐cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers

    Celine Lefebvre;Presha Rajbhandari;Mariano J. Alvarez;Pradeep Bandaru

  • Nuclear ARP2/3 drives DNA break clustering for homology-directed repair.

    Benjamin R. Schrank;Tomas Aparicio;Yinyin Li;Wakam Chang

  • Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells

    Emilie Rass;Anastazja Grabarz;Isabelle Plo;Jean Gautier

  • DNA double-strand break repair pathway choice and cancer.

    Tomas Aparicio;Richard Baer;Jean Gautier

  • Dephosphorylation and activation of Xenopus p34cdc2 protein kinase during the cell cycle.

    Jean Gautier;Toru Matsukawa;Paul Nurse;James Maller

  • Mammalian growth-associated H1 histone kinase: a homolog of cdc2+/CDC28 protein kinases controlling mitotic entry in yeast and frog cells.

    T A Langan;J Gautier;M Lohka;R Hollingsworth

  • Programmed Cell Death during Xenopus Development: A Spatio-temporal Analysis

    Carmel Hensey;Jean Gautier

  • Two-step activation of ATM by DNA and the Mre11-Rad50-Nbs1 complex.

    Aude Dupré;Louise Boyer-Chatenet;Jean Gautier

  • Mre11 Protein Complex Prevents Double-Strand Break Accumulation during Chromosomal DNA Replication

    Vincenzo Costanzo;Kirsten Robertson;Marina Bibikova;Edward Kim

  • Single-stranded DNA-binding protein hSSB1 is critical for genomic stability

    Derek J. Richard;Emma Bolderson;Liza Cubeddu;Liza Cubeddu;Ross I. M. Wadsworth

  • Regulation of DNA replication by ATR: signaling in response to DNA intermediates.

    David Shechter;Vincenzo Costanzo;Jean Gautier

  • Reconstitution of an ATM-Dependent Checkpoint that Inhibits Chromosomal DNA Replication following DNA Damage

    Vincenzo Costanzo;Kirsten Robertson;Carol Y. Ying;Edward Kim

Frequent Co-Authors

Vincenzo Costanzo
Vincenzo Costanzo University of Catania
Max E. Gottesman
Max E. Gottesman Columbia University Medical Center
James L. Maller
James L. Maller University of Colorado Denver
Richard Baer
Richard Baer Columbia University
Tanya T. Paull
Tanya T. Paull The University of Texas at Austin
Mohammad Athar
Mohammad Athar University of Alabama at Birmingham
David R. Bickers
David R. Bickers Columbia University
Enrico V. Avvedimento
Enrico V. Avvedimento University of Naples Federico II
Brian T. Chait
Brian T. Chait Rockefeller University
Paul Nurse
Paul Nurse The Francis Crick Institute

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