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Johannes C. Walter

Johannes C. Walter

D-Index & Metrics

Molecular Biology

D-Index
71
Citations
19991
World Ranking
1372
National Ranking
696

Research.com Recognitions

  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Johannes C. Walter is affiliated with Harvard University in the United States. Their research primarily falls within the field of Biochemistry, Genetics and Molecular Biology, with a strong focus on Molecular Biology, Cell Biology, Oncology, Genetics, and Neurology as subfields.

The topics of Johannes C. Walter's work cover several areas including DNA Repair Mechanisms, CRISPR and Genetic Engineering, Genomics and Chromatin Dynamics, Microtubule and mitosis dynamics, RNA modifications and cancer, RNA Research and Splicing, and Ubiquitin and proteasome pathways.

Some of the recent papers authored or co-authored by Walter include:

  • The cooperative action of CSB, CSA, and UVSSA target TFIIH to DNA damage-stalled RNA polymerase II (2020, Nature Communications)
  • Mechanisms of Vertebrate DNA Interstrand Cross-Link Repair (2021, Annual Review of Biochemistry)
  • Single-strand DNA breaks cause replisome disassembly (2021, Molecular Cell)
  • In silico protein interaction screening uncovers DONSON's role in replication initiation (2023, Science)
  • ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation (2021, Nature Cell Biology)

Johannes C. Walter has collaborated frequently with several co-authors, including E. Schmid, Tycho E.T. Mevissen, Ronghu Wu, Olga V. Kochenova, and Joseph J. Loparo. Their work has been published extensively in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Molecular Cell, Science, and Nature.

Walter was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2008.

Best Publications

  • Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint

    Tony S. Byun;Marcin Pacek;Muh-ching Yee;Johannes C. Walter

  • Inhibition of eukaryotic DNA replication by geminin binding to Cdt1.

    James A. Wohlschlegel;Brian T. Dwyer;Suman K. Dhar;Christin Cvetic

  • Self-assembling protein microarrays.

    Niroshan Ramachandran;Eugenie Hainsworth;Bhupinder Bhullar;Samuel Eisenstein

  • A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.

    Jianping Jin;Emily E. Arias;Jing Chen;J. Wade Harper

  • Initiation of Eukaryotic DNA Replication

    Johannes Walter;John Newport

  • Mechanism of replication-coupled DNA interstrand crosslink repair.

    Markus Räschle;Puck Knipscheer;Milica Enoiu;Todor Angelov

  • The nucleosomal surface as a docking station for Kaposi's sarcoma herpesvirus LANA.

    Andrew J. Barbera;Jayanth V. Chodaparambil;Brenna Kelley-Clarke;Vladimir Joukov

  • The Fanconi Anemia Pathway Promotes Replication-Dependent DNA Interstrand Cross-Link Repair

    Puck Knipscheer;Markus Räschle;Agata Smogorzewska;Agata Smogorzewska;Milica Enoiu

  • Strength in numbers: preventing rereplication via multiple mechanisms in eukaryotic cells

    Emily E. Arias;Johannes C. Walter

  • Localization of MCM2-7, Cdc45, and GINS to the Site of DNA Unwinding during Eukaryotic DNA Replication

    Marcin Pacek;Antonin V. Tutter;Yumiko Kubota;Haruhiko Takisawa

  • Selective Bypass of a Lagging Strand Roadblock by the Eukaryotic Replicative DNA Helicase

    Yu V. Fu;Hasan Yardimci;David T. Long

  • PCNA functions as a molecular platform to trigger Cdt1 destruction and prevent re-replication

    Emily E Arias;Johannes C Walter

  • Sequence-independent DNA binding and replication initiation by the human origin recognition complex

    Sanjay Vashee;Christin Cvetic;Wenyan Lu;Pamela Simancek

  • MCM2-7 complexes bind chromatin in a distributed pattern surrounding the origin recognition complex in Xenopus egg extracts.

    Melissa C. Edwards;Antonin V. Tutter;Christin Cvetic;Catherine H. Gilbert

  • Regulated Chromosomal DNA Replication in the Absence of a Nucleus

    Johannes Walter;Li Sun;John Newport

  • A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication.

    Marcin Pacek;Johannes C Walter

  • The BRCA1/BARD1 heterodimer modulates ran-dependent mitotic spindle assembly.

    Vladimir Joukov;Aaron C. Groen;Tatyana Prokhorova;Ruth Gerson

  • XPF-ERCC1 Acts in Unhooking DNA Interstrand Crosslinks in Cooperation with FANCD2 and FANCP/SLX4

    Daisy Klein Douwel;Rick A C M Boonen;David T Long;Anna A Szypowska

  • Mechanism of CRL4Cdt2, a PCNA-dependent E3 ubiquitin ligase

    Courtney G. Havens;Johannes C. Walter

  • Mechanism of Replication-Coupled DNA Interstrand Crosslink Repair (DOI:10.1016/j.cell.2008.08.030)

    Markus Räschle;Puck Knipscheer;Milica Enoiu;Todor Angelov

Frequent Co-Authors

Antoine M. van Oijen
Antoine M. van Oijen Illawarra Health and Medical Research Institute
Orlando D. Schärer
Orlando D. Schärer Institute for Basic Science
Matthias Mann
Matthias Mann Max Planck Institute of Biochemistry
Jerard Hurwitz
Jerard Hurwitz Memorial Sloan Kettering Cancer Center
David Pellman
David Pellman Howard Hughes Medical Institute
Jacob E. Corn
Jacob E. Corn ETH Zurich
John W. Newport
John W. Newport University of California, San Diego
Jack D. Griffith
Jack D. Griffith University of North Carolina at Chapel Hill
Anindya Dutta
Anindya Dutta University of Alabama at Birmingham
Gernot Walter
Gernot Walter University of California, San Diego

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