D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 113 Citations 38,140 346 World Ranking 195 National Ranking 121

Research.com Recognitions

Awards & Achievements

2016 - Fellow of the American Association for the Advancement of Science (AAAS)

1974 - Member of the National Academy of Sciences

1968 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

His primary areas of study are Molecular biology, DNA replication, Biochemistry, DNA and DNA clamp. The study incorporates disciplines such as Helicase, DNA polymerase delta, DNA polymerase, DNA polymerase II and Proliferating cell nuclear antigen in addition to Molecular biology. His study in DNA polymerase is interdisciplinary in nature, drawing from both Base pair and Primase.

The various areas that Jerard Hurwitz examines in his DNA replication study include Replication protein A and Cell biology. His DNA study combines topics in areas such as Recombinant DNA, Antigen, DNA-binding protein, Enzyme and Virus. His research integrates issues of Biophysics and Polymerase in his study of DNA clamp.

His most cited work include:

  • Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex (1222 citations)
  • The formation of 2-keto-3-deoxyheptonic acid in extracts of Escherichia coli B. I. Identification. (664 citations)
  • Structure of the C-Terminal Region of p21WAF1/CIP1 Complexed with Human PCNA (656 citations)

What are the main themes of his work throughout his whole career to date?

Jerard Hurwitz spends much of his time researching Molecular biology, Biochemistry, DNA replication, DNA and DNA polymerase. His Molecular biology research is multidisciplinary, incorporating perspectives in DNA clamp, Polymerase, DNA polymerase delta, Replication factor C and DNA polymerase II. Jerard Hurwitz combines subjects such as Processivity and Proliferating cell nuclear antigen with his study of DNA polymerase delta.

His DNA replication study integrates concerns from other disciplines, such as Replication protein A and Cell biology. His DNA research includes themes of In vitro, Gene and Helicase. The concepts of his DNA polymerase study are interwoven with issues in Okazaki fragments, Primase, Primer and Base pair.

He most often published in these fields:

  • Molecular biology (62.82%)
  • Biochemistry (42.82%)
  • DNA replication (39.72%)

What were the highlights of his more recent work (between 2003-2017)?

  • DNA replication (39.72%)
  • Molecular biology (62.82%)
  • Cell biology (13.52%)

In recent papers he was focusing on the following fields of study:

Jerard Hurwitz mainly investigates DNA replication, Molecular biology, Cell biology, Biochemistry and DNA polymerase. His studies in DNA replication integrate themes in fields like DNA polymerase delta and DNA clamp. His DNA polymerase delta research is multidisciplinary, relying on both Processivity and Replication protein A.

The DNA clamp study which covers DNA polymerase II that intersects with DNA polymerase mu. His Molecular biology research incorporates elements of Helicase, Replication factor C, DNA polymerase I, Proliferating cell nuclear antigen and Ubiquitin ligase. His work on DNA as part of general Biochemistry study is frequently connected to Thermococcus, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.

Between 2003 and 2017, his most popular works were:

  • Selective Bypass of a Lagging Strand Roadblock by the Eukaryotic Replicative DNA Helicase (283 citations)
  • Regulation of the Histone H4 Monomethylase PR-Set7 by CRL4Cdt2-Mediated PCNA-Dependent Degradation during DNA Damage (195 citations)
  • Human SHPRH is a ubiquitin ligase for Mms2-Ubc13-dependent polyubiquitylation of proliferating cell nuclear antigen. (172 citations)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

Philip D. Jeffrey;Alicia A. Russo;Kornelia Polyak;Emma Gibbs.
Nature (1995)

1847 Citations

The formation of 2-keto-3-deoxyheptonic acid in extracts of Escherichia coli B. I. Identification.

Arthur Weissbach;Arthur Weissbach;Jerard Hurwitz;Jerard Hurwitz.
Journal of Biological Chemistry (1959)

1250 Citations

Structure of the C-Terminal Region of p21WAF1/CIP1 Complexed with Human PCNA

Jacqueline M Gulbis;Zvi Kelman;Jerard Hurwitz;Mike O'Donnell;Mike O'Donnell.
Cell (1996)

920 Citations

Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1.

Yan Luo;Jerard Hurwitz;Joan Massagué.
Nature (1995)

803 Citations

RNA Helicase A Mediates Association of CBP with RNA Polymerase II

Toshihiro Nakajima;Chiharu Uchida;Stephen F. Anderson;Chee-Gun Lee.
Cell (1997)

668 Citations

Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme

H. Flores-Rozas;Z. Kelman;F. B. Dean;Zhen-Qiang Pan.
Proceedings of the National Academy of Sciences of the United States of America (1994)

620 Citations

The role of deoxyribonucleic acid in ribonucleic acid synthesis. III. The inhibition of the enzymatic synthesis of ribonucleic acid and deoxyribonucleic acid by actinomycin D and proflavin.

Jerard Hurwitz;J. J. Furth;M. Malamy;M. Alexander.
Proceedings of the National Academy of Sciences of the United States of America (1962)

559 Citations

Binding and unwinding—How T antigen engages the SV40 origin of DNA replication

James A. Borowiec;Frank B. Dean;Peter A. Bullock;Jerard Hurwitz.
Cell (1990)

516 Citations

Adenovirus DNA replication in vitro: identification of a host factor that stimulates synthesis of the preterminal protein-dCMP complex

Kyosuke Nagata;Ronald A. Guggenheimer;Takemi Enomoto;Jack H. Lichy.
Proceedings of the National Academy of Sciences of the United States of America (1982)

414 Citations

Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro

Vladimir P. Bermudez;Laura A. Lindsey-Boltz;Anthony J. Cesare;Yoshimasa Maniwa.
Proceedings of the National Academy of Sciences of the United States of America (2003)

402 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Jerard Hurwitz

Mike O'Donnell

Mike O'Donnell

Rockefeller University

Publications: 192

Stewart Shuman

Stewart Shuman

Kettering University

Publications: 80

Ulrich Hübscher

Ulrich Hübscher

University of Zurich

Publications: 65

Bruce Stillman

Bruce Stillman

Cold Spring Harbor Laboratory

Publications: 61

John Kuriyan

John Kuriyan

University of California, Berkeley

Publications: 59

Robert A. Bambara

Robert A. Bambara

University of Rochester

Publications: 58

Johannes C. Walter

Johannes C. Walter

Howard Hughes Medical Institute

Publications: 57

Peter M. J. Burgers

Peter M. J. Burgers

Washington University in St. Louis

Publications: 52

Yoshizumi Ishino

Yoshizumi Ishino

Kyushu University

Publications: 52

Anindya Dutta

Anindya Dutta

University of Virginia

Publications: 51

Richard M. Gronostajski

Richard M. Gronostajski

University at Buffalo, State University of New York

Publications: 47

Louise Prakash

Louise Prakash

The University of Texas Medical Branch at Galveston

Publications: 47

Satya Prakash

Satya Prakash

The University of Texas Medical Branch at Galveston

Publications: 47

Ellen Fanning

Ellen Fanning

Vanderbilt University

Publications: 43

Fumio Hanaoka

Fumio Hanaoka

National Institute of Genetics

Publications: 42

Arthur Kornberg

Arthur Kornberg

Stanford University

Publications: 41

Trending Scientists

David A. Bader

David A. Bader

New Jersey Institute of Technology

Anita Schöbel

Anita Schöbel

Technical University of Kaiserslautern

J.K. Hedrick

J.K. Hedrick

University of California, Berkeley

Pierre D. Harvey

Pierre D. Harvey

Université de Sherbrooke

Jean-François Joanny

Jean-François Joanny

Collège de France

Cornelis J.F. Van Noorden

Cornelis J.F. Van Noorden

University of Amsterdam

Francisco J. Florencio

Francisco J. Florencio

University of Seville

Dirk Zeller

Dirk Zeller

University of Western Australia

Jehee Lee

Jehee Lee

Jeju National University

Ole Bøssing Christensen

Ole Bøssing Christensen

Danish Meteorological Institute

Giovanni Marsicano

Giovanni Marsicano

University of Bordeaux

Donato Alarcón-Segovia

Donato Alarcón-Segovia

Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

Amit Bernstein

Amit Bernstein

University of Haifa

Madonna G. Constantine

Madonna G. Constantine

Columbia University

William T. Carpenter

William T. Carpenter

University of Maryland, Baltimore

Johan W. Groothoff

Johan W. Groothoff

University Medical Center Groningen

Something went wrong. Please try again later.