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Genetics and Molecular Biology
Japan
2024

D-Index & Metrics

Genetics

D-Index
98
Citations
35735
World Ranking
809
National Ranking
28

Molecular Biology

D-Index
98
Citations
35735
World Ranking
572
National Ranking
41

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in Japan Leader Award

Overview

Fumio Hanaoka is affiliated with the National Institute of Genetics in Japan and specializes in research within the fields of biochemistry, genetics, and molecular biology. Their work encompasses multiple subfields including molecular biology, genetics, physiology, food science, and plant science.

Hanaoka's research primarily focuses on several topics related to DNA and cellular mechanisms. These include:

  • DNA Repair Mechanisms
  • DNA and Nucleic Acid Chemistry
  • CRISPR and Genetic Engineering
  • Ubiquitin and proteasome pathways
  • Genetics and Neurodevelopmental Disorders
  • Telomeres, Telomerase, and Senescence
  • Genomics and Chromatin Dynamics

Their recent publications reflect a strong emphasis on DNA repair and molecular interactions involved in genome maintenance. Notable papers include:

  • Lesion recognition by XPC, TFIIH and XPA in DNA excision repair, 2023, Nature
  • Functional impacts of the ubiquitin-proteasome system on DNA damage recognition in global genome nucleotide excision repair, 2020, Scientific Reports
  • The intrinsically disordered N-terminal region of mouse DNA polymerase alpha mediates its interaction with POT1a/b at telomeres, 2021, Genes to Cells
  • A formamidopyrimidine derivative from the deoxyguanosine adduct produced by food contaminant acrylamide induces DNA replication block and mutagenesis, 2023, Journal of Biological Chemistry
  • Lesion recognition by XPC, TFIIH and XPA in DNA excision repair, 2023, Acta Crystallographica Section A Foundations and Advances

Frequent collaborators working alongside Hanaoka include:

  • Kaoru Sugasawa
  • Xuemin Chen
  • Yanxiang Cui
  • Filip Gołębiowski
  • Huaibin Wang

Hanaoka's publications have appeared in several scientific journals known for publishing research in molecular biology and biochemistry, including:

  • Nature
  • Scientific Reports
  • Genes to Cells
  • Journal of Biological Chemistry
  • Acta Crystallographica Section A Foundations and Advances

Best Publications

  • The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta.

    Chikahide Masutani;Rika Kusumoto;Rika Kusumoto;Ayumi Yamada;Naoshi Dohmae

  • Xeroderma Pigmentosum Group C Protein Complex Is the Initiator of Global Genome Nucleotide Excision Repair

    Kaoru Sugasawa;Jessica M.Y Ng;Chikahide Masutani;Shigenori Iwai

  • The Y-Family of DNA Polymerases

    Haruo Ohmori;Errol C. Friedberg;Robert P.P. Fuchs;Myron F. Goodman

  • Azathioprine and UVA Light Generate Mutagenic Oxidative DNA Damage

    Peter O'Donovan;Conal M. Perrett;Xiaohong Zhang;Beatriz Montaner

  • UV-Induced Ubiquitylation of XPC Protein Mediated by UV-DDB-Ubiquitin Ligase Complex

    Kaoru Sugasawa;Yuki Okuda;Masafumi Saijo;Ryotaro Nishi

  • Mechanisms of accurate translesion synthesis by human DNA polymerase η

    Chikahide Masutani;Rika Kusumoto;Shigenori Iwai;Fumio Hanaoka

  • A multistep damage recognition mechanism for global genomic nucleotide excision repair

    Kaoru Sugasawa;Tomoko Okamoto;Yuichiro Shimizu;Chikahide Masutani

  • Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity.

    Chikahide Masutani;Marito Araki;Ayumi Yamada;Rika Kusumoto;Rika Kusumoto

  • The comings and goings of nucleotide excision repair factors on damaged DNA

    Thilo Riedl;Fumio Hanaoka;Jean‐Marc Egly

  • Low fidelity DNA synthesis by human DNA polymerase-η

    Toshiro Matsuda;Katarzyna Bebenek;Chikahide Masutani;Fumio Hanaoka

  • The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activation.

    Eric S. Fischer;Andrea Scrima;Kerstin Böhm;Syota Matsumoto

  • Centrosome Protein Centrin 2/Caltractin 1 Is Part of the Xeroderma Pigmentosum Group C Complex That Initiates Global Genome Nucleotide Excision Repair

    Marito Araki;Chikahide Masutani;Mitsuyo Takemura;Akio Uchida

  • Both hypertrophic and dilated cardiomyopathies are caused by mutation of the same gene, δ-sarcoglycan, in hamster: An animal model of disrupted dystrophin-associated glycoprotein complex

    Aiji Sakamoto;Kageyoshi Ono;Makoto Abe;Gaëten Jasmin

  • Eukaryotic DNA polymerases: proposal for a revised nomenclature.

    Peter M J Burgers;Eugene V. Koonin;Elspeth Bruford;Luis Blanco

  • Crystal Structure of the MazE/MazF Complex. Molecular Bases of Antidote-Toxin Recognition

    Katsuhiko Kamada;Katsuhiko Kamada;Fumio Hanaoka;Stephen K. Burley;Stephen K. Burley

  • Domain structure, localization, and function of DNA polymerase η, defective in xeroderma pigmentosum variant cells

    Patricia Kannouche;Bernard C. Broughton;Marcel Volker;Fumio Hanaoka

  • Structure and mechanism of human DNA polymerase η

    Christian Biertümpfel;Ye Zhao;Ye Zhao;Yuji Kondo;Santiago Ramón-Maiques;Santiago Ramón-Maiques

  • Interaction of hHR23 with S5a. The ubiquitin-like domain of hHR23 mediates interaction with S5a subunit of 26 S proteasome.

    Hideki Hiyama;Masayuki Yokoi;Chikahide Masutani;Kaoru Sugasawa

  • The Xeroderma Pigmentosum Group C Protein Complex XPC-HR23B Plays an Important Role in the Recruitment of Transcription Factor IIH to Damaged DNA

    Masayuki Yokoi;Chikahide Masutani;Takafumi Maekawa;Kaoru Sugasawa

  • Error-prone bypass of certain DNA lesions by the human DNA polymerase κ

    Eiji Ohashi;Tomoo Ogi;Rika Kusumoto;Rika Kusumoto;Shigenori Iwai

Frequent Co-Authors

Chikahide Masutani
Chikahide Masutani Nagoya University
Kaoru Sugasawa
Kaoru Sugasawa Kobe University
Shigenori Iwai
Shigenori Iwai Osaka University
Takemi Enomoto
Takemi Enomoto Musashino University
Jan H.J. Hoeijmakers
Jan H.J. Hoeijmakers Erasmus University Rotterdam
Toshio Mori
Toshio Mori Nara Medical University
Roger Woodgate
Roger Woodgate National Institutes of Health
Takeshi Mizuno
Takeshi Mizuno Nagoya University
Takehiko Nohmi
Takehiko Nohmi Gifu University

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