World's Best Scientists 2026 revealed!
Shigenori Iwai

Shigenori Iwai

D-Index & Metrics

Chemistry

D-Index
67
Citations
19824
World Ranking
6793
National Ranking
441

Molecular Biology

D-Index
77
Citations
24581
World Ranking
1104
National Ranking
89

Overview

Shigenori Iwai is affiliated with Osaka University in Japan and specializes in the field of Biochemistry, Genetics and Molecular Biology, with a significant focus on Molecular Biology as evidenced by 51 publications.

Their research work largely revolves around DNA repair mechanisms and genetic engineering, with specific attention to DNA and nucleic acid chemistry as well as carcinogens and genotoxicity assessment. Additional areas of study include advanced biosensing and bioanalysis techniques, RNA and protein synthesis mechanisms, and the effects of light on plants.

Frequent publication venues for Iwai include:

  • Nucleic Acids Research
  • Journal of Biological Chemistry
  • Photochemical & Photobiological Sciences
  • Proceedings of the National Academy of Sciences
  • Genes and Environment

The scientist's recent papers include:

  • "Topoisomerase I-driven repair of UV-induced damage in NER-deficient cells," 2020, Proceedings of the National Academy of Sciences
  • "Effects of acetaldehyde-induced DNA lesions on DNA metabolism," 2020, Genes and Environment
  • "Novel mechanisms for the removal of strong replication-blocking HMCES- and thiazolidine-DNA adducts in humans," 2023, Nucleic Acids Research
  • "Enhanced DNA repair by DNA photolyase bearing an artificial light-harvesting chromophore," 2020, Nucleic Acids Research
  • "Acetaldehyde induces NER repairable mutagenic DNA lesions," 2021, Carcinogenesis

Frequent co-authors collaborating with Iwai include:

  • Junpei Yamamoto
  • Isao Kuraoka
  • Keiichiro Suzuki
  • Miyako Shiraishi
  • Narumi Shioi

The primary topics covered in Iwai's research are:

  • DNA Repair Mechanisms
  • CRISPR and Genetic Engineering
  • DNA and Nucleic Acid Chemistry
  • Advanced biosensing and bioanalysis techniques
  • Carcinogens and Genotoxicity Assessment
  • RNA and protein synthesis mechanisms
  • Light effects on plants

Best Publications

  • The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta.

    Chikahide Masutani;Rika Kusumoto;Rika Kusumoto;Ayumi Yamada;Naoshi Dohmae

  • Xeroderma Pigmentosum Group C Protein Complex Is the Initiator of Global Genome Nucleotide Excision Repair

    Kaoru Sugasawa;Jessica M.Y Ng;Chikahide Masutani;Shigenori Iwai

  • Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues

    Y Kuchino;F Mori;H Kasai;H Inoue

  • Synthesis and hybridization studies on two complementary nona(2'-O-methyl)ribonucleotides.

    Hideo Inoue;Yoji Hayase;Akihiro Imura;Shigenori Iwai

  • UV-Induced Ubiquitylation of XPC Protein Mediated by UV-DDB-Ubiquitin Ligase Complex

    Kaoru Sugasawa;Yuki Okuda;Masafumi Saijo;Ryotaro Nishi

  • Mechanisms of accurate translesion synthesis by human DNA polymerase η

    Chikahide Masutani;Rika Kusumoto;Shigenori Iwai;Fumio Hanaoka

  • A multistep damage recognition mechanism for global genomic nucleotide excision repair

    Kaoru Sugasawa;Tomoko Okamoto;Yuichiro Shimizu;Chikahide Masutani

  • Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity.

    Chikahide Masutani;Marito Araki;Ayumi Yamada;Rika Kusumoto;Rika Kusumoto

  • Sequence-dependent hydrolysis of RNA using modified oligonucleotide splints and RNase H

    Hideo Inoue;Yoji Hayase;Shigenori Iwai;Eiko Ohtsuka

  • Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex.

    Andrea Scrima;Renata Koníčková;Bryan K. Czyzewski;Yusuke Kawasaki

  • The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activation.

    Eric S. Fischer;Andrea Scrima;Kerstin Böhm;Syota Matsumoto

  • Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain.

    H. Itoh;T. Kozasa;S. Nagata;S. Nakamura

  • Identification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondria

    Toshio Ohtsubo;Kenichi Nishioka;Yasuyuki Imaiso;Shigenori Iwai

  • The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation.

    A Scrima;E.S Fischer;S Iwai;H Gut

  • Error-prone bypass of certain DNA lesions by the human DNA polymerase κ

    Eiji Ohashi;Tomoo Ogi;Rika Kusumoto;Rika Kusumoto;Shigenori Iwai

  • Preferential cis-syn thymine dimer bypass by DNA polymerase η occurs with biased fidelity

    Scott D McCulloch;Robert J Kokoska;Chikahide Masutani;Shigenori Iwai

  • Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): an archaeal DinB-like DNA polymerase with lesion-bypass properties akin to eukaryotic polη

    François Boudsocq;Shigenori Iwai;Fumio Hanaoka;Roger Woodgate

  • Atomic model of a pyrimidine dimer excision repair enzyme complexed with a dna substrate: Structural basis for damaged DNA recognition

    Dmitry G. Vassylyev;Tatsuki Kashiwagi;Yuriko Mikami;Mariko Ariyoshi

  • Centrin 2 stimulates nucleotide excision repair by interacting with xeroderma pigmentosum group C protein.

    Ryotaro Nishi;Yuki Okuda;Eriko Watanabe;Toshio Mori

  • The intricate structural chemistry of base excision repair machinery: implications for DNA damage recognition, removal, and repair.

    Kenichi Hitomi;Shigenori Iwai;John A. Tainer

Frequent Co-Authors

Fumio Hanaoka
Fumio Hanaoka National Institute of Genetics
Eiko Ohtsuka
Eiko Ohtsuka Hokkaido University
Takeshi Todo
Takeshi Todo Osaka University
Elizabeth D. Getzoff
Elizabeth D. Getzoff Scripps Research Institute
Chikahide Masutani
Chikahide Masutani Nagoya University
Kaoru Sugasawa
Kaoru Sugasawa Kobe University
Hideki Kandori
Hideki Kandori Nagoya Institute of Technology
Morio Ikehara
Morio Ikehara Osaka University
John A. Tainer
John A. Tainer The University of Texas MD Anderson Cancer Center
Haruki Nakamura
Haruki Nakamura Osaka University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Students interested in Molecular Biology often explore a range of online degrees and career options to expand their expertise and future opportunities. Online education offers flexibility, making it suitable for individuals with diverse backgrounds and commitments.

For those who are actively serving or are veterans, many online colleges for military provide flexible programs and strong support networks. These institutions are designed to accommodate unique schedules and needs, helping service members pursue their educational goals in tandem with their commitments.

Professionals looking to pivot to people-centric roles may consider degrees beyond biology. The online masters of social work and online masters in mental health counseling prepare students for vital positions in healthcare and support services. These programs teach critical skills that complement a scientific background.

If time is a concern, options like the accelerated masters in psychology allow motivated students to complete their education faster, entering the workforce sooner. Each of these pathways can enrich a molecular biology foundation, open up interdisciplinary careers, and boost professional flexibility.

Best Scientists Citing Shigenori Iwai

Trending Scientists