Shigenori Iwai mostly deals with Biochemistry, Nucleotide excision repair, Molecular biology, DNA damage and DNA polymerase. His study looks at the relationship between Biochemistry and fields such as Stereochemistry, as well as how they intersect with chemical problems. His Nucleotide excision repair research is multidisciplinary, relying on both Pyrimidine dimer, Xeroderma pigmentosum and Cell biology.
His research on DNA damage concerns the broader DNA. His DNA polymerase study combines topics in areas such as DNA polymerase II and Polymerase. His studies deal with areas such as DNA polymerase delta, DNA clamp, DNA polymerase I and DNA replication as well as DNA polymerase II.
His primary areas of investigation include DNA, Biochemistry, Molecular biology, Stereochemistry and Pyrimidine dimer. Much of his study explores DNA relationship to Pyrimidine. His research integrates issues of Xeroderma pigmentosum, DNA polymerase eta, DNA polymerase delta and Gene, DNA polymerase in his study of Molecular biology.
The DNA polymerase study combines topics in areas such as DNA polymerase II, Polymerase, DNA clamp and DNA replication. His work in Stereochemistry addresses subjects such as RNase H, which are connected to disciplines such as Cleavage. Shigenori Iwai works mostly in the field of DNA damage, limiting it down to concerns involving DNA repair and, occasionally, Mutant.
His scientific interests lie mostly in DNA, DNA repair, Biochemistry, DNA damage and Molecular biology. His study explores the link between DNA repair and topics such as DNA clamp that cross with problems in Flap endonuclease. His Pyrimidine dimer, Thymine, DNA glycosylase and Endonuclease study, which is part of a larger body of work in Biochemistry, is frequently linked to Ultraviolet light, bridging the gap between disciplines.
His studies in DNA damage integrate themes in fields like Mutation, DNA replication and A-DNA. His Molecular biology research includes elements of Nucleotide excision repair, DNA repair protein XRCC4, Inosine, Ribonuclease and Transfection. Shigenori Iwai has included themes like Base pair, Transcription and DNA polymerase II in his DNA polymerase study.
Shigenori Iwai mainly investigates DNA, DNA repair, DNA damage, Molecular biology and Nucleotide excision repair. His DNA study is related to the wider topic of Biochemistry. His DNA repair research incorporates elements of RNA, Ribonuclease, Endoribonuclease and Inosine.
His work in DNA damage covers topics such as DNA replication which are related to areas like DNA synthesis. The concepts of his Molecular biology study are interwoven with issues in Mutation, Ubiquitin, Xeroderma pigmentosum and DNA ligase. His Nucleotide excision repair research is multidisciplinary, incorporating elements of DNA photolyase, Photochemistry, Dimer and Photon.
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The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta.
Chikahide Masutani;Rika Kusumoto;Rika Kusumoto;Ayumi Yamada;Naoshi Dohmae.
Nature (1999)
Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues
Y Kuchino;F Mori;H Kasai;H Inoue.
Nature (1987)
Xeroderma Pigmentosum Group C Protein Complex Is the Initiator of Global Genome Nucleotide Excision Repair
Kaoru Sugasawa;Jessica M.Y Ng;Chikahide Masutani;Shigenori Iwai.
Molecular Cell (1998)
Synthesis and hybridization studies on two complementary nona(2'-O-methyl)ribonucleotides.
Hideo Inoue;Yoji Hayase;Akihiro Imura;Shigenori Iwai.
Nucleic Acids Research (1987)
Mechanisms of accurate translesion synthesis by human DNA polymerase η
Chikahide Masutani;Rika Kusumoto;Shigenori Iwai;Fumio Hanaoka.
The EMBO Journal (2000)
UV-Induced Ubiquitylation of XPC Protein Mediated by UV-DDB-Ubiquitin Ligase Complex
Kaoru Sugasawa;Yuki Okuda;Masafumi Saijo;Ryotaro Nishi.
Cell (2005)
Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity.
Chikahide Masutani;Marito Araki;Ayumi Yamada;Rika Kusumoto;Rika Kusumoto.
The EMBO Journal (1999)
A multistep damage recognition mechanism for global genomic nucleotide excision repair
Kaoru Sugasawa;Tomoko Okamoto;Yuichiro Shimizu;Chikahide Masutani.
Genes & Development (2001)
Sequence-dependent hydrolysis of RNA using modified oligonucleotide splints and RNase H
Hideo Inoue;Yoji Hayase;Shigenori Iwai;Eiko Ohtsuka.
FEBS Letters (1987)
Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex.
Andrea Scrima;Renata Koníčková;Bryan K. Czyzewski;Yusuke Kawasaki.
Cell (2008)
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