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Kaoru Sugasawa

Kaoru Sugasawa

D-Index & Metrics

Molecular Biology

D-Index
55
Citations
13509
World Ranking
2256
National Ranking
176

Overview

Kaoru Sugasawa is affiliated with Kobe University in Japan and has contributed extensively to research in biochemistry, genetics, and molecular biology. Their work primarily centers on molecular biology with notable involvement in cell biology, genetics, cancer research, and immunology.

Their research covers a range of topics, including DNA repair mechanisms, DNA and nucleic acid chemistry, CRISPR and genetic engineering, carcinogens and genotoxicity assessment, glycosylation and glycoproteins research, endoplasmic reticulum stress and disease, as well as galectins and cancer biology.

Sugasawa has authored multiple papers, including:

  • Lesion recognition by XPC, TFIIH and XPA in DNA excision repair, 2023, Nature
  • Functional impacts of the ubiquitin-proteasome system on DNA damage recognition in global genome nucleotide excision repair, 2020, Scientific Reports
  • Human SIRT2 and SIRT3 deacetylases function in DNA homologous recombinational repair, 2021, Genes to Cells
  • USP44 Stabilizes DDB2 to Facilitate Nucleotide Excision Repair and Prevent Tumors, 2021, Frontiers in Cell and Developmental Biology
  • Histone deacetylation regulates nucleotide excision repair through an interaction with the XPC protein, 2022, iScience

The venues where Sugasawa frequently publishes include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biological Chemistry
  • PLoS ONE
  • eLife
  • Nature

Co-authors regularly collaborating with Sugasawa are:

  • Masayuki Yokoi
  • Wataru Sakai
  • Fumio Hanaoka
  • Masayuki Kusakabe
  • Takeshi Yasuda

Best Publications

  • Xeroderma Pigmentosum Group C Protein Complex Is the Initiator of Global Genome Nucleotide Excision Repair

    Kaoru Sugasawa;Jessica M.Y Ng;Chikahide Masutani;Shigenori Iwai

  • UV-Induced Ubiquitylation of XPC Protein Mediated by UV-DDB-Ubiquitin Ligase Complex

    Kaoru Sugasawa;Yuki Okuda;Masafumi Saijo;Ryotaro Nishi

  • A multistep damage recognition mechanism for global genomic nucleotide excision repair

    Kaoru Sugasawa;Tomoko Okamoto;Yuichiro Shimizu;Chikahide Masutani

  • Purification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homologue of yeast RAD23.

    C. Masutani;K. Sugasawa;J. Yanagisawa;T. Sonoyama

  • The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activation.

    Eric S. Fischer;Andrea Scrima;Kerstin Böhm;Syota Matsumoto

  • Centrosome Protein Centrin 2/Caltractin 1 Is Part of the Xeroderma Pigmentosum Group C Complex That Initiates Global Genome Nucleotide Excision Repair

    Marito Araki;Chikahide Masutani;Mitsuyo Takemura;Akio Uchida

  • DNA-binding polarity of human replication protein A positions nucleases in nucleotide excision repair

    Wouter L. de Laat;Esther Appeldoorn;Kaoru Sugasawa;Eric Weterings

  • Interaction of hHR23 with S5a. The ubiquitin-like domain of hHR23 mediates interaction with S5a subunit of 26 S proteasome.

    Hideki Hiyama;Masayuki Yokoi;Chikahide Masutani;Kaoru Sugasawa

  • The Xeroderma Pigmentosum Group C Protein Complex XPC-HR23B Plays an Important Role in the Recruitment of Transcription Factor IIH to Damaged DNA

    Masayuki Yokoi;Chikahide Masutani;Takafumi Maekawa;Kaoru Sugasawa

  • Centrin 2 stimulates nucleotide excision repair by interacting with xeroderma pigmentosum group C protein.

    Ryotaro Nishi;Yuki Okuda;Eriko Watanabe;Toshio Mori

  • A novel regulation mechanism of DNA repair by damage-induced and RAD23-dependent stabilization of xeroderma pigmentosum group C protein

    Jessica M.Y. Ng;Wim Vermeulen;Gijsbertus T.J. van der Horst;Steven Bergink

  • PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1

    Alex Pines;Mischa G. Vrouwe;Jurgen A. Marteijn;Dimitris Typas

  • Crystal structure of thymine DNA glycosylase conjugated to SUMO-1

    Daichi Baba;Nobuo Maita;Jun Goo Jee;Yasuhiro Uchimura

  • Two-step recognition of DNA damage for mammalian nucleotide excision repair: Directional binding of the XPC complex and DNA strand scanning.

    Kaoru Sugasawa;Jun-ichi Akagi;Ryotaro Nishi;Shigenori Iwai

  • A molecular mechanism for DNA damage recognition by the xeroderma pigmentosum group C protein complex.

    Kaoru Sugasawa;Yuichiro Shimizu;Shigenori Iwai;Fumio Hanaoka

  • DNA repair protein XPA binds replication protein A (RPA)

    Toshiro Matsuda;Masafumi Saijo;Isao Kuraoka;Takehiro Kobayashi

  • HHR23B, a Human Rad23 Homolog, Stimulates XPC Protein in Nucleotide Excision Repair In Vitro

    K. Sugasawa;C. Masutani;A. Uchida;T. Maekawa

  • Tripartite DNA Lesion Recognition and Verification by XPC, TFIIH, and XPA in Nucleotide Excision Repair

    Chia-Lung Li;Filip M. Golebiowski;Yuki Onishi;Nadine L. Samara

  • Cullin–RING ubiquitin E3 ligase regulation by the COP9 signalosome

    Simone Cavadini;Simone Cavadini;Eric S. Fischer;Richard D. Bunker;Richard D. Bunker;Alessandro Potenza;Alessandro Potenza

  • Purification and initial characterization of a protein which facilitates assembly of nucleosome-like structure from mammalian cells.

    Yukio Ishimi;Jiro Hirosumi;Wakao Sato;Kaoru Sugasawa

Frequent Co-Authors

Fumio Hanaoka
Fumio Hanaoka National Institute of Genetics
Shigenori Iwai
Shigenori Iwai Osaka University
Chikahide Masutani
Chikahide Masutani Nagoya University
Jan H.J. Hoeijmakers
Jan H.J. Hoeijmakers Erasmus University Rotterdam
Hitoshi Kurumizaka
Hitoshi Kurumizaka University of Tokyo
Toshio Mori
Toshio Mori Nara Medical University
Wim Vermeulen
Wim Vermeulen Erasmus University Rotterdam
Masahiro Shirakawa
Masahiro Shirakawa Kyoto University
Dirk Bootsma
Dirk Bootsma Erasmus University Rotterdam

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