John DiGiovanni

Research.com Recognitions

• 2015 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• Multistage carcinogenesis in mouse skin

  John DiGiovanni

  933
  Citations

• Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model

  Shigetoshi Sano;Shigetoshi Sano;Keith Syson Chan;Steve Carbajal;John Clifford

  879
  Citations

• Multi-stage chemical carcinogenesis in mouse skin: Fundamentals and applications

  Erika L Abel;Joe M Angel;Kaoru Kiguchi;John DiGiovanni

  702
  Citations

• DISRUPTION OF STAT3 REVEALS A CRITICAL ROLE IN BOTH THE INITIATION AND THE PROMOTION STAGES OF EPITHELIAL CARCINOGENESIS

  Keith Syson Chan;Shigetoshi Sano;Kaoru Kiguchi;Joanne Anders

  485
  Citations

• Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth

  Shira L. Cramer;Achinto Saha;Jinyun Liu;Surendar Tadi

  472
  Citations

• Deregulated expression of insulin-like growth factor 1 in prostate epithelium leads to neoplasia in transgenic mice.

  John DiGiovanni;Kaoru Kiguchi;Anita Frijhoff;Eric Wilker

  352
  Citations

• Cancer as a Matter of Fat: The Crosstalk between Adipose Tissue and Tumors.

  Ernst Lengyel;Liza Makowski;John DiGiovanni;Mikhail G. Kolonin

  337
  Citations

• Stat3 as a Therapeutic Target for the Treatment of Psoriasis: A Clinical Feasibility Study with STA-21, a Stat3 Inhibitor

  Ken Miyoshi;Mikiro Takaishi;Kimiko Nakajima;Mitsunori Ikeda

  314
  Citations

• Constitutive expression of insulin-like growth factor-1 in epidermal basal cells of transgenic mice leads to spontaneous tumor promotion

  John DiGiovanni;David K. Bol;David K. Bol;Erik Wilker;Linda M Beltran

  284
  Citations

• Mechanism-Based Cancer Prevention Approaches: Targets, Examples, and the Use of Transgenic Mice

  Stephen D. Hursting;Thomas J. Slaga;Susan M. Fischer;John DiGiovanni

  231
  Citations

• Genome-wide expression profiling of five mouse models identifies similarities and differences with human psoriasis.

  William R. Swindell;Andrew Johnston;Steve Carbajal;Gangwen Han

  229
  Citations

• Constitutive expression of ErbB-2 in gallbladder epithelium results in development of adenocarcinoma

  Kaoru Kiguchi;Steve Carbajal;Keith Chan;Linda Beltrán

  226
  Citations

• Impact of Stat3 activation upon skin biology: A dichotomy of its role between homeostasis and diseases

  Shigetoshi Sano;Keith Syson Chan;John DiGiovanni

  223
  Citations

• Distinct Roles of IL-23 and IL-17 in the Development of Psoriasis-Like Lesions in a Mouse Model

  Kimiko Nakajima;Takashi Kanda;Mikiro Takaishi;Takeo Shiga

  219
  Citations

• Obesity, Energy Balance and Cancer: New Opportunities for Prevention

  Stephen D. Hursting;John DiGiovanni;Andrew J. Dannenberg;Maria Azrad

  204
  Citations

• Overexpression of Insulin-Like Growth factor-1 Induces Hyperplasia, Dermal Abnormalities, and Spontaneous Tumor Formation in Transgenic Mice

  David K. Bol;Kaoru Kiguchi;Irma Gimenez-Conti;Tim Rupp

  199
  Citations

• Dietary energy balance modulates signaling through the Akt/mammalian target of rapamycin pathways in multiple epithelial tissues.

  Tricia Moore;Tricia Moore;Linda M Beltran;Steve Carbajal;Sara Strom

  195
  Citations

• Epidermal growth factor receptor-mediated activation of Stat3 during multistage skin carcinogenesis.

  Keith Syson Chan;Steve Carbajal;Kaoru Kiguchi;John Clifford

  195
  Citations

• Comparison of the tumor-initiating activity of 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene in female SENCAR and CD-1 mice

  J. Digiovanni;Thomas J Slaga;Thomas J Slaga;R. K. Boutwell;R. K. Boutwell

  159
  Citations

• IKKα Is Required to Maintain Skin Homeostasis and Prevent Skin Cancer

  Bigang Liu;Xiaojun Xia;Feng Zhu;Eunmi Park

  158
  Citations