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Molecular Biology

D-Index
52
Citations
9091
World Ranking
2444
National Ranking
1204

Overview

Jianjun Shen is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to subfields such as Molecular Biology, Surgery, Cancer Research, Oncology, and Plant Science.

The main topics of Jianjun Shen's work include:

  • Anesthesia and Pain Management
  • Genomics and Chromatin Dynamics
  • MicroRNA in disease regulation
  • Nausea and vomiting management
  • Epigenetics and DNA Methylation
  • Ubiquitin and proteasome pathways
  • Advanced biosensing and bioanalysis techniques

Jianjun Shen has published extensively with some frequent co-authors being Xinzhong Chen, Yue Lu, Bin Liu, Yanhong Zhou, and Lili Xu.

The scientist's work has appeared in several key publication venues including:

  • Nature Communications
  • Journal of Biomolecular Techniques JBT
  • International Journal of Surgery
  • PubMed
  • BMC Anesthesiology

Selected recent papers illustrating the range of their research include:

  • Celastrol Loaded Nanoparticles With ROS-Response and ROS-Inducer for the Treatment of Ovarian Cancer, 2020, Frontiers in Chemistry
  • Defining the mutation signatures of DNA polymerase θ in cancer genomes, 2020, NAR Cancer
  • The NFIB/CARM1 partnership is a driver in preclinical models of small cell lung cancer, 2023, Nature Communications
  • Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer, 2021, Nature Communications
  • Transcriptional Activation of MYC-Induced Genes by GCN5 Promotes B-cell Lymphomagenesis, 2020, Cancer Research

Best Publications

  • ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

    Angela Alexander;Sheng Li Cai;Jinhee Kim;Adrian Nanez

  • Protein Expression Profiles in Pancreatic Adenocarcinoma Compared with Normal Pancreatic Tissue and Tissue Affected by Pancreatitis as Detected by Two-Dimensional Gel Electrophoresis and Mass Spectrometry

    Jianjun Shen;Maria D. Person;Jijiang Zhu;James L. Abbruzzese

  • NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation

    Collene R. Jeter;Bigang Liu;Xin Liu;Xin Liu;Xin-Xin Chen

  • Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning.

    Sheng Li Cai;Andrew R. Tee;Johnny D Short;Judith M. Bergeron

  • Specific protein methylation defects and gene expression perturbations in coactivator-associated arginine methyltransferase 1-deficient mice.

    Neelu Yadav;Jaeho Lee;Jeesun Kim;Jianjun Shen

  • Locus-specific variation in phosphorylation state of RNA polymerase II in vivo: correlations with gene activity and transcript processing.

    J. R. Weeks;S. E. Hardin;Jianjun Shen;Jae Moon Lee

  • Constitutive expression of ErbB-2 in gallbladder epithelium results in development of adenocarcinoma

    Kaoru Kiguchi;Steve Carbajal;Keith Chan;Linda Beltrán

  • Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer

    Dingxiao Zhang;Daechan Park;Yi Zhong;Yue Lu

  • MicroRNA-141 suppresses prostate cancer stem cells and metastasis by targeting a cohort of pro-metastasis genes.

    Can Liu;Ruifang Liu;Ruifang Liu;Ruifang Liu;Dingxiao Zhang;Dingxiao Zhang;Qu Deng;Qu Deng;Qu Deng

  • Annexin II expression is reduced or lost in prostate cancer cells and its re-expression inhibits prostate cancer cell migration.

    Jun Wei Liu;Jian Jun Shen;Angela Tanzillo-Swarts;Bobby Bhatia

  • Immunotherapeutic Potential of Anti-Human Endogenous Retrovirus-K Envelope Protein Antibodies in Targeting Breast Tumors

    Feng Wang-Johanning;Kiera Rycaj;Joshua B. Plummer;Joshua B. Plummer;Ming Li;Ming Li

  • Mec1/Tel1 Phosphorylation of the INO80 Chromatin Remodeling Complex Influences DNA Damage Checkpoint Responses

    Ashby J. Morrison;Jung Ae Kim;Maria D. Person;Jessica Highland

  • Mutations in exon 3 of the glycogen debranching enzyme gene are associated with glycogen storage disease type III that is differentially expressed in liver and muscle.

    Jianjun Shen;Yong Bao;Hui Ming Liu;Philip Lee

  • A Molecular Portrait of High-Grade Ductal Carcinoma In Situ

    Martín Carlos Abba;Ting Gong;Yue Lu;Jaeho Lee

  • Evidence that arachidonate 15-lipoxygenase 2 is a negative cell cycle regulator in normal prostate epithelial cells.

    Shaohua Tang;Bobby Bhatia;Carlos J. Maldonado;Peiying Yang

  • DNMT3A and TET1 cooperate to regulate promoter epigenetic landscapes in mouse embryonic stem cells

    Tianpeng Gu;Xueqiu Lin;Sean M. Cullen;Min Luo

  • Cross-species identification of genomic drivers of squamous cell carcinoma development across preneoplastic intermediates.

    Vida Chitsazzadeh;Cristian Coarfa;Jennifer A. Drummond;Tri Nguyen

  • Up-regulation of 14-3-3ζ in lung cancer and its implication as prognostic and therapeutic target

    Tao Fan;Ruiyun Li;Nevins W. Todd;Qi Qiu

  • Prognostic Power of a Tumor Differentiation Gene Signature for Bladder Urothelial Carcinomas

    Qianxing Mo;Fotis Nikolos;Fengju Chen;Zoe Tramel

  • DNMT3L facilitates DNA methylation partly by maintaining DNMT3A stability in mouse embryonic stem cells

    Nicolas Veland;Yue Lu;Swanand Hardikar;Sally Gaddis

Frequent Co-Authors

Yue Lu
Yue Lu The University of Texas MD Anderson Cancer Center
Dean G. Tang
Dean G. Tang Roswell Park Cancer Institute
Yuan-Tsong Chen
Yuan-Tsong Chen Harbor–UCLA Medical Center
John DiGiovanni
John DiGiovanni The University of Texas at Austin
Cheryl L. Walker
Cheryl L. Walker Baylor College of Medicine
Mark T. Bedford
Mark T. Bedford The University of Texas MD Anderson Cancer Center
Xin Liu
Xin Liu Chinese Academy of Sciences
Gordon B. Mills
Gordon B. Mills Oregon Health & Science University
Sharon Y.R. Dent
Sharon Y.R. Dent The University of Texas MD Anderson Cancer Center
Mustafa Sahin
Mustafa Sahin Boston Children's Hospital

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