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Arno L. Greenleaf

Arno L. Greenleaf

D-Index & Metrics

Molecular Biology

D-Index
61
Citations
11383
World Ranking
1915
National Ranking
949

Overview

Arno L. Greenleaf is affiliated with Duke University in the United States and conducts research primarily in the fields of Biochemistry, Genetics, and Molecular Biology. The focus of their work spans several specialized areas, including molecular biology and RNA-related mechanisms.

The main topics of Greenleaf's research include:

  • RNA modifications and cancer
  • RNA Research and Splicing
  • RNA and protein synthesis mechanisms

Greenleaf has contributed to molecular biology through research that often intersects RNA biology and the regulation of genetic expression post-transcriptionally.

A notable recent publication authored by Greenleaf is:

  • CDK12 regulates co-transcriptional splicing and RNA turnover in human cells (2022, iScience)

This work aligns with Greenleaf's thematic interest in RNA dynamics and processing events affecting cellular function.

Greenleaf frequently collaborates with several researchers, including:

  • Brian Magnuson
  • Karan Bedi
  • Ishwarya Venkata Narayanan
  • Bartlomiej Bartkowiak
  • Hailey Blinkiewicz

These collaborations are reflected in joint scholarly publications and contribute to the multidisciplinary nature of Greenleaf's work.

The publication venues in which Greenleaf's work appears include:

  • iScience

This indicates engagement with outlets that focus on interdisciplinary scientific research.

Best Publications

  • Phosphorylation and functions of the RNA polymerase II CTD

    Hemali P. Phatnani;Arno L. Greenleaf

  • A Novel Domain in Set2 Mediates RNA Polymerase II Interaction and Couples Histone H3 K36 Methylation with Transcript Elongation

    Kelby O. Kizer;Hemali P. Phatnani;Yoichiro Shibata;Hana Hall

  • CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1

    Bartlomiej Bartkowiak;Pengda Liu;Hemali P. Phatnani;Nicholas J. Fuda

  • Phosphorylation of RNA polymerase II C-terminal domain and transcriptional elongation.

    Thomas O'Brien;Steven Hardin;Steven Hardin;Arno Greenleaf;John T. Lis

  • Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors

    Tinghu Zhang;Nicholas Kwiatkowski;Nicholas Kwiatkowski;Calla M Olson;Sarah E Dixon-Clarke

  • The Splicing Factor, Prp40, Binds the Phosphorylated Carboxyl-terminal Domain of RNA Polymerase II

    Daniel P. Morris;Arno L. Greenleaf

  • Dynamic interaction between a Drosophila transcription factor and RNA polymerase II.

    D H Price;A E Sluder;A L Greenleaf

  • Kin28, the TFIIH-Associated Carboxy-Terminal Domain Kinase, Facilitates the Recruitment of mRNA Processing Machinery to RNA Polymerase II

    Christine R. Rodriguez;Eun-Jung Cho;Michael-C. Keogh;Claire L. Moore

  • Analysis of the gene encoding the largest subunit of RNA polymerase II in Drosophila.

    R. S. Jokerst;J. R. Weeks;W. A. Zehring;A. L. Greenleaf

  • The C-terminal repeat domain of RNA polymerase II largest subunit is essential in vivo but is not required for accurate transcription initiation in vitro.

    W A Zehring;J M Lee;J R Weeks;R S Jokerst

  • Locus-specific variation in phosphorylation state of RNA polymerase II in vivo: correlations with gene activity and transcript processing.

    J. R. Weeks;S. E. Hardin;Jianjun Shen;Jae Moon Lee

  • Localization of RNA polymerase in polytene chromosomes of Drosophila melanogaster

    Milan Jamrich;Arno L. Greenleaf;Ekkehard K. F. Bautz

  • Co-transcriptional splicing of pre-messenger RNAs: considerations for the mechanism of alternative splicing

    Aaron C Goldstrohm;Arno L Greenleaf;Mariano A Garcia-Blanco

  • Juglone, an inhibitor of the peptidyl-prolyl isomerase Pin1, also directly blocks transcription.

    Sheng-Hao Chao;Arno L. Greenleaf;David H. Price

  • CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation.

    Malgorzata Krajewska;Ruben Dries;Andrew V. Grassetti;Sofia Dust

  • Yeast RPO41 gene product is required for transcription and maintenance of the mitochondrial genome.

    Arno L. Greenleaf;Jeffrey L. Kelly;I. R. Lehman

  • On the specificity of creatine kinase. New glycocyamines and glycocyamine analogs related to creatine.

    Gerald L. Rowley;Arno L. Greenleaf;George L. Kenyon

  • Phospho-carboxyl-terminal domain binding and the role of a prolyl isomerase in pre-mRNA 3'-End formation.

    Daniel P. Morris;Hemali P. Phatnani;Arno L. Greenleaf

  • C-terminal repeat domain kinase I phosphorylates Ser2 and Ser5 of RNA polymerase II C-terminal domain repeats.

    Janice C. Jones;Hemali P. Phatnani;Timothy A. Haystead;Justin A. MacDonald

  • Loss of the sigma activity of RNA polymerase of Bacillus subtilis during sporulation.

    Thomas G. Linn;Arno L. Greenleaf;Rosalind G. Shorenstein;Richard Losick

Frequent Co-Authors

Ekkehard K. F. Bautz
Ekkehard K. F. Bautz Heidelberg University
David H. Price
David H. Price University of Iowa
Matthias Geyer
Matthias Geyer University of Bonn
Richard Losick
Richard Losick Harvard University
Nathanael S. Gray
Nathanael S. Gray Stanford University
Tinghu Zhang
Tinghu Zhang Stanford University
Alex N. Bullock
Alex N. Bullock University of Oxford
Scott A. Gerber
Scott A. Gerber Dartmouth College
Scott B. Ficarro
Scott B. Ficarro Harvard University

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