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Molecular Biology

D-Index
78
Citations
40517
World Ranking
1057
National Ranking
553

Overview

Brian D. Strahl is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research predominantly lies within the field of Biochemistry, Genetics and Molecular Biology, focusing on subfields such as Molecular Biology, Plant Science, Cell Biology, Virology, and Infectious Diseases.

The research topics covered by Brian D. Strahl include:

  • Epigenetics and DNA Methylation
  • Genomics and Chromatin Dynamics
  • RNA modifications and cancer
  • Cancer-related gene regulation
  • Ubiquitin and proteasome pathways
  • RNA Research and Splicing
  • Protein Degradation and Inhibitors

Some of the recent papers authored or co-authored by Brian D. Strahl are:

  • DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation, 2021, Nature Communications
  • Characterization of the plant homeodomain (PHD) reader family for their histone tail interactions, 2020, Epigenetics & Chromatin
  • HDAC inhibition results in widespread alteration of the histone acetylation landscape and BRD4 targeting to gene bodies, 2021, Cell Reports
  • Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation, 2020, Proceedings of the National Academy of Sciences
  • BAHCC1 binds H3K27me3 via a conserved BAH module to mediate gene silencing and oncogenesis, 2020, Nature Genetics

Frequent co-authors collaborating with Brian D. Strahl include:

  • Krzysztof Krajewski
  • Scott B. Rothbart
  • Tatiana G. Kutateladze
  • Kanishk Jain
  • Gang Greg Wang

Brian D. Strahl's publications have appeared in various scientific venues. The most frequent venues include:

  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biological Chemistry
  • Nature Communications
  • eLife

Best Publications

  • The language of covalent histone modifications.

    B D Strahl;C D Allis

  • Regulation of chromatin structure by site-specific histone H3 methyltransferases

    S Rea;F Eisenhaber;D O'Carroll;B D Strahl

  • Role of Histone H3 Lysine 9 Methylation in Epigenetic Control of Heterochromatin Assembly

    Jun-ichi Nakayama;Judd C. Rice;Brian D. Strahl;C. David Allis

  • Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor

    Hengbin Wang;Zhi-Qing Huang;Li Xia;Qin Feng

  • Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex.

    Michael Christopher Keogh;Siavash K. Kurdistani;Stephanie A. Morris;Seong Hoon Ahn

  • Evidence for nucleosome depletion at active regulatory regions genome-wide.

    Cheol Koo Lee;Yoichiro Shibata;Bhargavi Rao;Brian D. Strahl

  • Interpreting the language of histone and DNA modifications

    Scott B. Rothbart;Brian D. Strahl

  • Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae

    Scott D. Briggs;Mary Bryk;Brian D. Strahl;Wang L. Cheung

  • Set2 Is a Nucleosomal Histone H3-Selective Methyltransferase That Mediates Transcriptional Repression

    Brian D Strahl;Patrick A. Grant;Scott D. Briggs;Zu Wen Sun

  • A nucleosomal function for IκB kinase-α in NF-κB-dependent gene expression

    Vasiliki Anest;Julie L. Hanson;Patricia C. Cogswell;Kris A. Steinbrecher

  • Methylation of histone H3 at lysine 4 is highly conserved and correlates with transcriptionally active nuclei in Tetrahymena

    Brian D. Strahl;Reiko Ohba;Richard G. Cook;C. David Allis

  • Gene silencing: Trans -histone regulatory pathway in chromatin

    Scott D. Briggs;Tiaojiang Xiao;Zu Wen Sun;Jennifer A. Caldwell

  • A Novel Domain in Set2 Mediates RNA Polymerase II Interaction and Couples Histone H3 K36 Methylation with Transcript Elongation

    Kelby O. Kizer;Hemali P. Phatnani;Yoichiro Shibata;Hana Hall

  • Role of protein methylation in regulation of transcription.

    David Y. Lee;Catherine Teyssier;Brian D. Strahl;Michael R. Stallcup

  • Methylation of histone H4 at arginine 3 occurs in vivo and is mediated by the nuclear receptor coactivator PRMT1

    Brian D. Strahl;Scott D. Briggs;Cynthia J. Brame;Jennifer A. Caldwell

  • Phosphorylation of RNA polymerase II CTD regulates H3 methylation in yeast

    Tiaojiang Xiao;Hana Hall;Kelby O. Kizer;Yoichiro Shibata

  • Long noncoding RNAs are rarely translated in two human cell lines

    Balázs Bánfai;Hui Jia;Jainab Khatun;Emily Wood

  • Histone H2B Ubiquitylation Is Associated with Elongating RNA Polymerase II

    Tiaojiang Xiao;Cheng Fu Kao;Nevan J. Krogan;Zu Wen Sun

  • OPERating ON chromatin, a colorful language where context matters

    Kathryn E. Gardner;C. David Allis;Brian D. Strahl

  • Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1

    Julie A. Law;Jiamu Du;Christopher J. Hale;Suhua Feng

Frequent Co-Authors

Tatiana G. Kutateladze
Tatiana G. Kutateladze University of Colorado Denver
C. David Allis
C. David Allis Rockefeller University
Robert J. Duronio
Robert J. Duronio University of North Carolina at Chapel Hill
A. Gregory Matera
A. Gregory Matera University of North Carolina at Chapel Hill
Nevan J. Krogan
Nevan J. Krogan University of California, San Francisco
Mark T. Bedford
Mark T. Bedford The University of Texas MD Anderson Cancer Center
Cheryl H. Arrowsmith
Cheryl H. Arrowsmith Structural Genomics Consortium
Xiaobing Shi
Xiaobing Shi Van Andel Institute
Dinshaw J. Patel
Dinshaw J. Patel Memorial Sloan Kettering Cancer Center
Benjamin A. Garcia
Benjamin A. Garcia Washington University in St. Louis

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