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D-Index & Metrics

Molecular Biology

D-Index
54
Citations
10755
World Ranking
2323
National Ranking
1146

Research.com Recognitions

  • 2012 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Robert J. Duronio is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with a total of 116 publications. Within these, the most significant subfield is Molecular Biology, which accounts for 110 publications. They have also contributed to Plant Science, Immunology, Oncology, and Cancer Research.

Their work covers several key topics, including:

  • Genomics and Chromatin Dynamics
  • Epigenetics and DNA Methylation
  • RNA Research and Splicing
  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • Cancer-related gene regulation
  • DNA Repair Mechanisms

Among their recent papers are the following, which illustrate their research focus and publication record:

  • CDK-Regulated Phase Separation Seeded by Histone Genes Ensures Precise Growth and Function of Histone Locus Bodies, 2020, published in Developmental Cell
  • Coordinating transcription and replication to mitigate their conflicts in early Drosophila embryos, 2022, published in Cell Reports
  • Superresolution light microscopy of the Drosophila histone locus body reveals a core-shell organization associated with expression of replication-dependent histone genes, 2021, published in Molecular Biology of the Cell
  • Distinct roles for canonical and variant histone H3 lysine-36 in Polycomb silencing, 2023, published in Science Advances
  • Drosophila histone locus body assembly and function involves multiple interactions, 2020, published in Molecular Biology of the Cell

Frequent coauthors in their research network include:

  • William F. Marzluff (19 joint publications)
  • Daniel J. McKay (17 joint publications)
  • A. Gregory Matera (13 joint publications)
  • James P. Kemp (9 joint publications)
  • Christina A. Hill (9 joint publications)

Duronio's work is regularly published in key venues such as:

  • UNC Libraries (40 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (10 publications)
  • Molecular Biology of the Cell (4 publications)
  • Genetics (4 publications)
  • Molecular Cell (2 publications)

In recognition of their contributions to science, Robert J. Duronio was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2012.

Best Publications

  • Metabolism and regulation of canonical histone mRNAs: life without a poly(A) tail

    William F. Marzluff;Eric J. Wagner;Robert J. Duronio

  • Endoreplication: polyploidy with purpose

    Hyun O. Lee;Jean M. Davidson;Robert J. Duronio

  • Signaling Pathways that Control Cell Proliferation

    Robert J. Duronio;Yue Xiong

  • Distinct molecular mechanisms regulate cell cycle timing at successive stages of Drosophila embryogenesis

    Brace A. Edgar;Frank Sprenger;Robert J. Duronio;Pierre Leopold

  • Lipid modifications of G protein subunits.: Myristoylation of Goα increases its affinity for βγ

    Maurine E. Linder;Iok Hou Pang;Robert J. Duronio;Jeffrey I. Gordon

  • Endoreplication and polyploidy: insights into development and disease

    Donald T. Fox;Robert J. Duronio

  • Protein N-myristoylation

    Jeffrey Gordon;R. J. Duronio;David Rudnick;S. P. Adams

  • Histone mRNA expression: multiple levels of cell cycle regulation and important developmental consequences.

    William F Marzluff;Robert J Duronio

  • The transcription factor E2F is required for S phase during Drosophila embryogenesis.

    R. J. Duronio;P. H. O'farrell;Jing-Er Xie;A. Brook

  • Protein N-myristoylation in Escherichia coli: reconstitution of a eukaryotic protein modification in bacteria.

    Robert J. Duronio;Emily Jackson-Machelski;Robert O. Heuckeroth;Peter O. Olins

  • Developmental control of the G1 to S transition in Drosophila: cyclin Eis a limiting downstream target of E2F.

    Robert J Duronio;Patrick H. O'Farrell

  • Disruption of the yeast N-myristoyl transferase gene causes recessive lethality

    Robert J. Duronio;Dwight A. Towler;Robert O. Heuckeroth;Jeffrey I. Gordon

  • Intrinsic Negative Cell Cycle Regulation Provided by PIP Box- and Cul4Cdt2-Mediated Destruction of E2f1 during S Phase

    Shusaku T. Shibutani;Aida Flor A. de la Cruz;Vuong Tran;William J. Turbyfill

  • WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1–CUL4–ROC1 ligase

    Jian Hu;Sima Zacharek;Sima Zacharek;Yizhou Joseph He;Hyun Lee

  • New insights into cell cycle control from the Drosophila endocycle

    Mary A Lilly;Robert J Duronio

  • Control of Drosophila endocycles by E2F and CRL4 CDT2

    Norman Zielke;Norman Zielke;Kerry J. Kim;Vuong Tran;Shusaku T. Shibutani

  • Drosophila stem loop binding protein coordinates accumulation of mature histone mRNA with cell cycle progression

    Eileen Sullivan;Carlos Santiago;Carlos Santiago;Emily D. Parker;Zbigniew Dominski

  • Interrogating the function of metazoan histones using engineered gene clusters

    Daniel J. McKay;Stephen Klusza;Taylor J.R. Penke;Michael P. Meers

  • E2F-induced S phase requires cyclin E.

    Robert J Duronio;Adam Brook;Nicholas Dyson;Patrick H. O'Farrell

  • Coordinating cell cycle-regulated histone gene expression through assembly and function of the Histone Locus Body

    Robert J. Duronio;William F. Marzluff

Frequent Co-Authors

William F. Marzluff
William F. Marzluff University of North Carolina at Chapel Hill
Jeffrey I. Gordon
Jeffrey I. Gordon Washington University in St. Louis
A. Gregory Matera
A. Gregory Matera University of North Carolina at Chapel Hill
Brian D. Strahl
Brian D. Strahl University of North Carolina at Chapel Hill
Patrick H. O'Farrell
Patrick H. O'Farrell University of California, San Francisco
Karen Adelman
Karen Adelman Harvard University
Yue Xiong
Yue Xiong University of North Carolina at Chapel Hill
Bruce A. Edgar
Bruce A. Edgar Huntsman Cancer Institute
Nicholas J. Dyson
Nicholas J. Dyson Harvard University
Michael Y. Tolstorukov
Michael Y. Tolstorukov Harvard University

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