2026 Michael Y. Tolstorukov: Molecular Biology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Molecular Biology	45	2833	2573	1357	1218	313	14418

Overview

Michael Y. Tolstorukov is affiliated with Harvard University in the United States.

Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on Oncology, Molecular Biology, Immunology, Pulmonary and Respiratory Medicine, and Genetics.

Main topics of their scientific work include:

Cancer Immunotherapy and Biomarkers
Cancer Genomics and Diagnostics
Immune Cell Function and Interaction
Lung Cancer Treatments and Mutations
Lung Cancer Research Studies
CAR-T cell therapy research
Interferon and immune responses

Their frequent publication venues include:

Cancer Research
bioRxiv (Cold Spring Harbor Laboratory)
Journal of Thoracic Oncology
Blood
Cancer Discovery

Frequent co-authors in their research collaborations are:

Matthew A. Booker
David A. Barbie
Navin R. Mahadevan
Patrick H. Lizotte
Elizabeth F. Cohen

Selected recent publications include:

Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer, 2021, Cell
Association of High Tumor Mutation Burden in Non-Small Cell Lung Cancers With Increased Immune Infiltration and Improved Clinical Outcomes of PD-L1 Blockade Across PD-L1 Expression Levels, 2022, JAMA Oncology
Diminished Efficacy of Programmed Death-(Ligand)1 Inhibition in STK11- and KEAP1-Mutant Lung Adenocarcinoma Is Affected by KRAS Mutation Status, 2021, Journal of Thoracic Oncology
Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC), 2022, Genetics in Medicine
Intrinsic Immunogenicity of Small Cell Lung Carcinoma Revealed by Its Cellular Plasticity, 2021, Cancer Discovery

Best Publications

ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia

Stephen G. Landt;Georgi K. Marinov;Anshul Kundaje;Pouya Kheradpour

2471
Citations
Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE

Sushmita Roy;Jason Ernst;Peter V. Kharchenko;Pouya Kheradpour

1266
Citations
Design and analysis of ChIP-seq experiments for DNA-binding proteins

Peter V Kharchenko;Michael Y Tolstorukov;Michael Y Tolstorukov;Peter J Park;Peter J Park;Peter J Park

1086
Citations
Comprehensive analysis of the chromatin landscape in Drosophila melanogaster

Peter V. Kharchenko;Artyom A. Alekseyenko;Artyom A. Alekseyenko;Yuri B. Schwartz;Aki Minoda

1006
Citations
The Long Noncoding RNAs NEAT1 and MALAT1 Bind Active Chromatin Sites

Jason A. West;Christopher P. Davis;Hongjae Sunwoo;Matthew D. Simon

673
Citations
Comparative analysis of metazoan chromatin organization

Joshua Wing Kei Ho;Joshua Wing Kei Ho;Youngsook L. Jung;Tao Liu;Tao Liu;Burak Han Alver

423
Citations
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate.

Abhishek A. Chakraborty;Tuomas Laukka;Matti Myllykoski;Alison E. Ringel

348
Citations
CpG Islands Recruit a Histone H3 Lysine 36 Demethylase

Neil P. Blackledge;Jin C. Zhou;Michael Y. Tolstorukov;Anca M. Farcas

335
Citations
SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation

Xiaofeng Wang;Xiaofeng Wang;Ryan S Lee;Ryan S Lee;Burak H Alver;Jeffrey R Haswell;Jeffrey R Haswell

317
Citations
Plasticity in patterns of histone modifications and chromosomal proteins in Drosophila heterochromatin

Nicole C. Riddle;Aki Minoda;Peter V. Kharchenko;Artyom A. Alekseyenko

270
Citations
Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway

Zainab Jagani;E. Lorena Mora-Blanco;Courtney G. Sansam;Elizabeth S. McKenna

268
Citations
A Novel ‘Roll-and-Slide’ Mechanism of DNA Folding in Chromatin. Implications for Nucleosome Positioning

Michael Y. Tolstorukov;Andrew V. Colasanti;David M. McCandlish;Wilma K. Olson

252
Citations
Diminished Efficacy of Programmed Death-(Ligand)1 Inhibition in STK11- and KEAP1-Mutant Lung Adenocarcinoma Is Affected by KRAS Mutation Status.

Biagio Ricciuti;Kathryn C. Arbour;Jessica J. Lin;Amir Vajdi

249
Citations
MNase titration reveals differences between nucleosome occupancy and chromatin accessibility

Jakub Mieczkowski;April Cook;Sarah K. Bowman;Britta Mueller

239
Citations
Swi/Snf chromatin remodeling/tumor suppressor complex establishes nucleosome occupancy at target promoters

Michael Y. Tolstorukov;Courtney G. Sansam;Courtney G. Sansam;Ping Lu;Ping Lu;Edward C. Koellhoffer;Edward C. Koellhoffer

199
Citations
Nature and function of insulator protein binding sites in the Drosophila genome

Yuri B. Schwartz;Yuri B. Schwartz;Daniela Linder-Basso;Peter V. Kharchenko;Michael Y. Tolstorukov

198
Citations
Impact of sequencing depth in ChIP-seq experiments

Youngsook L. Jung;Lovelace J. Luquette;Joshua W.K. Ho;Francesco Ferrari

190
Citations
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells

Michael Y. Tolstorukov;Michael Y. Tolstorukov;Joseph A. Goldman;Cristele Gilbert;Vasily Ogryzko

140
Citations
The CLAMP protein links the MSL complex to the X chromosome during Drosophila dosage compensation

Marcela M.L. Soruco;Jessica Chery;Eric P. Bishop;Eric P. Bishop;Trevor Siggers

137
Citations
Intrinsic Immunogenicity of Small Cell Lung Carcinoma Revealed by Its Cellular Plasticity.

Navin R. Mahadevan;Navin R. Mahadevan;Erik H. Knelson;Jacquelyn O. Wolff;Amir Vajdi

132
Citations

Frequent Co-Authors

Peter J. Park Harvard University

Peter V. Kharchenko Harvard University

Robert E. Kingston Harvard University

Gary H. Karpen University of California, Berkeley

Mitzi I. Kuroda Brigham and Women's Hospital

Sarah C. R. Elgin Washington University in St. Louis

Victor B. Zhurkin National Institutes of Health

Manolis Kellis MIT

Bradley E. Bernstein Broad Institute

William G. Kaelin Harvard University

External Links

Personal website of Michael Y. Tolstorukov

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