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Molecular Biology

D-Index
47
Citations
7838
World Ranking
2751
National Ranking
1325

Overview

Victor B. Zhurkin is affiliated with the National Institutes of Health in the United States. Their research spans a broad area within biochemistry, genetics, and molecular biology, with a strong focus on molecular biology as reflected in the predominance of their publications in this subfield. Their research contributions cover several scientific topics including genomics and chromatin dynamics, RNA modifications and cancer, epigenetics and DNA methylation, cancer genomics and diagnostics, histone deacetylase inhibitors research, cancer-related gene regulation, and RNA and protein synthesis mechanisms.

The scientist has authored multiple papers across a variety of journals and research venues. Some notable publications include:

  • Topological polymorphism of nucleosome fibers and folding of chromatin, 2021, Biophysical Journal
  • Nucleosome reorganisation in breast cancer tissues, 2024, Clinical Epigenetics
  • The Methyltransferases METTL7A and METTL7B Confer Resistance to Thiol-Based Histone Deacetylase Inhibitors, 2023, Molecular Cancer Therapeutics
  • The methyltransferases METTL7A and METTL7B confer resistance to thiol-based histone deacetylase inhibitors, 2022, bioRxiv (Cold Spring Harbor Laboratory)
  • Histone N-tails modulate sequence-specific positioning of nucleosomes, 2024, Journal of Biological Chemistry

Victor B. Zhurkin collaborates frequently with several colleagues. Frequent co-authors include Wilfried M. Guiblet, Divya R. Jacob, Hulkar Mamayusupova, Mariya Shtumpf, and Isabella Ciuta, highlighting sustained collaborative research efforts.

The scientist's work is published mainly in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biophysical Journal
  • Clinical Epigenetics
  • Molecular Cancer Therapeutics
  • Journal of Biological Chemistry

Victor B. Zhurkin's research consistently addresses central questions in genomics and chromatin structure, mechanisms of RNA modification, epigenetic regulation, and cancer biology. Their investigations into the role of histone deacetylase inhibitors and nucleosome organization contribute to the understanding of gene regulation and molecular responses in cancer and other biological contexts.

Best Publications

  • DNA sequence-dependent deformability deduced from protein–DNA crystal complexes

    Wilma K. Olson;Andrey A. Gorin;Xiang-Jun Lu;Lynette M. Hock

  • B-DNA Twisting Correlates with Base-pair Morphology

    A A Gorin;V B Zhurkin;V B Zhurkin;W K Olson

  • Anisotropic flexibility of DNA and the nucleosomal structure

    Victor B. Zhurkin;Yury P. Lysov;Valery I. Ivanov

  • A Novel ‘Roll-and-Slide’ Mechanism of DNA Folding in Chromatin. Implications for Nucleosome Positioning

    Michael Y. Tolstorukov;Andrew V. Colasanti;David M. McCandlish;Wilma K. Olson

  • Modeling DNA deformations.

    Wilma K Olson;Victor B Zhurkin

  • A role for CH...O interactions in protein-DNA recognition.

    Yael Mandel-Gutfreund;Hanah Margalit;Robert L Jernigan;Victor B Zhurkin

  • DNA stretching and compression: large-scale simulations of double helical structures

    Konstantin M. Kosikov;Andrey A. Gorin;Victor B. Zhurkin;Wilma K. Olson

  • Static and statistical bending of DNA evaluated by Monte Carlo simulations.

    V B Zhurkin;N B Ulyanov;A A Gorin;R L Jernigan

  • Influence of fluctuations on DNA curvature. A comparison of flexible and static wedge models of intrinsically bent DNA.

    Wilma K. Olson;Nancy L. Marky;Robert L. Jernigan;Victor B. Zhurkin

  • Overall structure and sugar dynamics of a DNA dodecamer from homo- and heteronuclear dipolar couplings and 31P chemical shift anisotropy.

    Zhengrong Wu;Frank Delaglio;Nico Tjandra;Victor B. Zhurkin

  • A Parallel DNA Triplex as model for the Intermediate in Homologous Recombination

    V.B. Zhurkin;G. Raghunathan;N.B. Ulyanov;R.D. Camerini-Otero

  • Structural basis for SRY-dependent 46-X,Y sex reversal: modulation of DNA bending by a naturally occurring point mutation.

    E C Murphy;V B Zhurkin;J M Louis;G Cornilescu

  • p53-induced DNA bending and twisting: p53 tetramer binds on the outer side of a DNA loop and increases DNA twisting

    Akhilesh K. Nagaich;Victor B. Zhurkin;Stewart R. Durell;Robert L. Jernigan

  • Correlations between deoxyribonucleic acid structural parameters and calculated circular dichroism spectra.

    Bruce B. Johnson;Kenneth S. Dahl;Ignacio Tinoco;Valery I. Ivanov

  • Coupling between Histone Conformations and DNA Geometry in Nucleosomes on a Microsecond Timescale: Atomistic Insights into Nucleosome Functions

    Alexey K. Shaytan;Grigoriy A. Armeev;Alexander Goncearenco;Victor B. Zhurkin

  • Sequence-Dependent Anisotropic Flexibility of B-DNA A Conformational Study

    Nikolai B. Ulyanov;Victor B. Zhurkin

  • [Atom--atomic potential functions for conformational calculations of nucleic acids].

    Zhurkin Vb;Poltev Vi;Florent'ev Vl

  • Impact of Alu repeats on the evolution of human p53 binding sites

    Feng Cui;Michael V Sirotin;Victor B Zhurkin

  • Gal repressosome contains an antiparallel DNA loop.

    Mark Geanacopoulos;George Vasmatzis;Victor B. Zhurkin;Sankar Adhya

  • A mutant spacer sequence between -35 and -10 elements makes the Plac promoter hyperactive and cAMP receptor protein-independent.

    Mofang Liu;Michael Tolstorukov;Victor Zhurkin;Susan Garges

Frequent Co-Authors

Wilma K. Olson
Wilma K. Olson Rutgers, The State University of New Jersey
Sankar Adhya
Sankar Adhya National Institutes of Health
Robert L. Jernigan
Robert L. Jernigan Iowa State University
Michael Y. Tolstorukov
Michael Y. Tolstorukov Harvard University
Ettore Appella
Ettore Appella National Institutes of Health
David Landsman
David Landsman National Institutes of Health
Anna R. Panchenko
Anna R. Panchenko Queen's University
Donna J. Arndt-Jovin
Donna J. Arndt-Jovin Max Planck Society
Thomas M. Jovin
Thomas M. Jovin Max Planck Society
David Clark
David Clark University of Glasgow

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