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Anna R. Panchenko

Anna R. Panchenko

D-Index & Metrics

Molecular Biology

D-Index
59
Citations
17442
World Ranking
2003
National Ranking
61

Overview

Anna R. Panchenko is affiliated with Queen's University in Canada and specializes in research primarily within the fields of biochemistry, genetics, and molecular biology. Their work focuses extensively on molecular biology, cancer research, genetics, information systems, and epidemiology, covering a broad spectrum of scientific inquiry.

The scientist's research topics include:

  • Genomics and Chromatin Dynamics
  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • Cancer Genomics and Diagnostics
  • Bioinformatics and Genomic Networks
  • RNA Research and Splicing
  • DNA and Nucleic Acid Chemistry

Anna R. Panchenko has published in various venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biophysical Journal
  • Journal of Molecular Biology
  • Nucleic Acids Research
  • SSRN Electronic Journal

Some of the recent papers authored or co-authored include:

  • MutaBind2: Predicting the Impacts of Single and Multiple Mutations on Protein-Protein Interactions (2020, iScience)
  • Clonal Evolution and Heterogeneity of Osimertinib Acquired Resistance Mechanisms in EGFR Mutant Lung Cancer (2020, Cell Reports Medicine)
  • Distinct Structures and Dynamics of Chromatosomes with Different Human Linker Histone Isoforms (2020, Molecular Cell)
  • DNA methylation: Precise modulation of chromatin structure and dynamics (2022, Current Opinion in Structural Biology)
  • Cancer driver mutations: predictions and reality (2023, Trends in Molecular Medicine)

Their frequent collaborators include:

  • Shuxiang Li
  • David Landsman
  • Yunhui Peng
  • Daniel Espiritu
  • Daria Ostroverkhova

Best Publications

  • CDD: a curated Entrez database of conserved domain alignments

    Aron Marchler-Bauer;John B. Anderson;Carol DeWeese-Scott;Natalie D. Fedorova

  • CDD: a database of conserved domain alignments with links to domain three-dimensional structure

    Aron Marchler-Bauer;Anna R. Panchenko;Benjamin A. Shoemaker;Paul A. Thiessen

  • Deciphering Protein–Protein Interactions. Part I. Experimental Techniques and Databases

    Benjamin A Shoemaker;Anna R Panchenko

  • Deciphering protein-protein interactions. Part II. Computational methods to predict protein and domain interaction partners.

    Benjamin A Shoemaker;Anna R Panchenko

  • Phosphorylation in Protein-Protein Binding: Effect on Stability and Function

    Hafumi Nishi;Kosuke Hashimoto;Anna R. Panchenko

  • Molecular Mechanisms of Disease-Causing Missense Mutations

    Shannon Stefl;Hafumi Nishi;Marharyta Petukh;Anna R. Panchenko

  • MMDB: Entrez's 3D structure database

    Yanli Wang;John B. Anderson;Jie Chen;Lewis Y. Geer

  • Foldons, protein structural modules, and exons

    Anna R. Panchenko;Zaida Ann Luthey-Schulten;Peter G. Wolynes

  • Physicochemical mechanisms of protein regulation by phosphorylation.

    Hafumi Nishi;Alexey Shaytan;Anna R. Panchenko

  • Mechanisms of protein oligomerization, the critical role of insertions and deletions in maintaining different oligomeric states

    Kosuke Hashimoto;Anna R. Panchenko

  • The relationship of protein conservation and sequence length

    David J Lipman;Alexander Souvorov;Eugene V Koonin;Anna R Panchenko

  • Prediction of functional sites by analysis of sequence and structure conservation

    Anna R. Panchenko;Fyodor Kondrashov;Stephen Bryant

  • MutaBind2: Predicting the Impacts of Single and Multiple Mutations on Protein-Protein Interactions.

    Ning Zhang;Yuting Chen;Haoyu Lu;Feiyang Zhao

  • Combination of threading potentials and sequence profiles improves fold recognition.

    Anna R Panchenko;Aron Marchler-Bauer;Stephen H Bryant

  • MMDB: 3D structures and macromolecular interactions

    Thomas Madej;Kenneth J. Addess;Jessica H. Fong;Lewis Y. Geer

  • Intrinsic Disorder in Protein Interactions: Insights From a Comprehensive Structural Analysis

    Jessica H. Fong;Benjamin A. Shoemaker;Sergiy O. Garbuzynskiy;Michail Yu. Lobanov

  • Modeling Effects of Human Single Nucleotide Polymorphisms on Protein-Protein Interactions

    Shaolei Teng;Thomas Madej;Anna Panchenko;Emil Alexov

  • Coupling between Histone Conformations and DNA Geometry in Nucleosomes on a Microsecond Timescale: Atomistic Insights into Nucleosome Functions

    Alexey K. Shaytan;Grigoriy A. Armeev;Alexander Goncearenco;Victor B. Zhurkin

  • HistoneDB 2.0: a histone database with variants--an integrated resource to explore histones and their variants.

    Eli J. Draizen;Alexey K. Shaytan;Leonardo Mariño-Ramírez;Paul B. Talbert

  • Cancer Missense Mutations Alter Binding Properties of Proteins and Their Interaction Networks

    Hafumi Nishi;Manoj Tyagi;Shaolei Teng;Benjamin A. Shoemaker

Frequent Co-Authors

Stephen H. Bryant
Stephen H. Bryant National Institutes of Health
David Landsman
David Landsman National Institutes of Health
Aron Marchler-Bauer
Aron Marchler-Bauer National Institutes of Health
Teresa M. Przytycka
Teresa M. Przytycka National Institutes of Health
Igor B. Rogozin
Igor B. Rogozin National Institutes of Health
Victor B. Zhurkin
Victor B. Zhurkin National Institutes of Health
Youri I. Pavlov
Youri I. Pavlov University of Nebraska Medical Center
Stephen M. Hewitt
Stephen M. Hewitt National Institutes of Health
Peter G. Wolynes
Peter G. Wolynes Rice University
David Neil Cooper
David Neil Cooper Cardiff University

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