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Margaret R. MacDonald

Margaret R. MacDonald

D-Index & Metrics

Microbiology

D-Index
45
Citations
7794
World Ranking
5013
National Ranking
1936

Overview

Margaret R. MacDonald is affiliated with Rockefeller University in the United States. Their research predominantly falls within the fields of Medicine and Immunology and Microbiology. The scientist's subfields of focus include Infectious Diseases, Public Health, Environmental and Occupational Health, Immunology, Epidemiology, and Molecular Biology.

The main research topics covered by their work are:

  • Mosquito-borne diseases and control
  • Viral Infections and Vectors
  • SARS-CoV-2 and COVID-19 Research
  • Interferon and immune responses
  • Vector-borne infectious diseases
  • CRISPR and Genetic Engineering
  • Insect symbiosis and bacterial influences

MacDonald's recent publications demonstrate a focus on viral infections and immune response mechanisms. Notable papers include:

  • "Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks," 2020, Cell
  • "Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever live attenuated vaccine," 2021, The Journal of Experimental Medicine
  • "TMEM41B Is a Pan-flavivirus Host Factor," 2020, Cell
  • "Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors," 2020, Cell Host & Microbe
  • "Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria," 2023, Cell

Frequently collaborating with other researchers, MacDonald has multiple partnerships. Their most frequent coauthors include:

  • Charles M. Rice
  • Avery Peace
  • Hans-Heinrich Hoffmann
  • Alison W. Ashbrook
  • William M. Schneider

MacDonald's work is often published in prominent scientific venues. The most frequent publication venues are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Experimental Medicine
  • Cell
  • Proceedings of the National Academy of Sciences
  • PLoS Pathogens

Best Publications

  • Interferons α and λ Inhibit Hepatitis C Virus Replication With Distinct Signal Transduction and Gene Regulation Kinetics

    Tobias Marcello;Arash Grakoui;Giovanna Barba-Spaeth;Erica S. Machlin

  • Expression of the Zinc-Finger Antiviral Protein Inhibits Alphavirus Replication

    Matthew J. Bick;John-William N. Carroll;Guangxia Gao;Stephen P. Goff

  • Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks.

    William M. Schneider;Joseph M. Luna;H.-Heinrich Hoffmann;Francisco J. Sánchez-Rivera

  • Intrinsic Immunity Shapes Viral Resistance of Stem Cells

    Xianfang Wu;Viet Loan Dao Thi;Yumin Huang;Yumin Huang;Eva Billerbeck

  • Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico.

    Davide F. Robbiani;Leonia Bozzacco;Jennifer R. Keeffe;Ricardo Khouri

  • The Zinc Finger Antiviral Protein Directly Binds to Specific Viral mRNAs through the CCCH Zinc Finger Motifs

    Xuemin Guo;John-William N. Carroll;Margaret R. MacDonald;Stephen P. Goff

  • Real-time imaging of hepatitis C virus infection using a fluorescent cell-based reporter system

    Christopher T Jones;Maria Teresa Catanese;Lok Man J Law;Salman R Khetani

  • Tracking and elucidating alphavirus-host protein interactions

    Ileana M. Cristea;John William N. Carroll;Michael P. Rout;Charles M. Rice

  • Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever live attenuated vaccine.

    Paul Bastard;Paul Bastard;Paul Bastard;Eleftherios Michailidis;Hans-Heinrich Hoffmann;Marwa Chbihi;Marwa Chbihi

  • TRIM25 Enhances the Antiviral Action of Zinc-Finger Antiviral Protein (ZAP).

    Melody M. H. Li;Zerlina Lau;Pamela Cheung;Eduardo G. Aguilar

  • TMEM41B Is a Pan-flavivirus Host Factor.

    H.-Heinrich Hoffmann;William M. Schneider;Kathryn Rozen-Gagnon;Linde A. Miles

  • Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response

    Terry C. Fang;Uwe Schaefer;Ingrid Mecklenbrauker;Astrid Stienen;Astrid Stienen

  • Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reaction to measles and yellow fever live vaccines

    Nicholas Hernandez;Giorgia Bucciol;Leen Moens;Jérémie Le Pen

  • Prenylome profiling reveals S-farnesylation is crucial for membrane targeting and antiviral activity of ZAP long-isoform

    Guillaume Charron;Melody M. H. Li;Margaret R. MacDonald;Howard C. Hang

  • Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors.

    H.-Heinrich Hoffmann;Francisco J. Sánchez-Rivera;William M. Schneider;Joseph M. Luna

  • Host Factors Associated with the Sindbis Virus RNA-Dependent RNA Polymerase: Role for G3BP1 and G3BP2 in Virus Replication†

    Ileana M. Cristea;Heather Rozjabek;Kelly R. Molloy;Sophiya Karki

  • Multiple tachykinins are produced and secreted upon post-translational processing of the three substance P precursor proteins, alpha-, beta-, and gamma-preprotachykinin. Expression of the preprotachykinins in AtT-20 cells infected with vaccinia virus recombinants.

    M R MacDonald;J Takeda;C M Rice;J E Krause

  • Structure of the zinc-finger antiviral protein in complex with RNA reveals a mechanism for selective targeting of CG-rich viral sequences.

    Jennifer L Meagher;Matthew Takata;Daniel Gonçalves-Carneiro;Sarah C Keane

  • The Zinc Finger Antiviral Protein Acts Synergistically with an Interferon-Induced Factor for Maximal Activity against Alphaviruses

    Margaret R. MacDonald;Erica S. Machlin;Owen R. Albin;David E. Levy

  • Sindbis Virus Translation Is Inhibited by a PKR/RNase L-Independent Effector Induced by Alpha/Beta Interferon Priming of Dendritic Cells

    K. D. Ryman;K. C. Meier;E. M. Nangle;S. L. Ragsdale

  • Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria

    Unknown

  • Spliced mRNA Encoding the Murine Cytomegalovirus Chemokine Homolog Predicts a β Chemokine of Novel Structure

    Margaret R. MacDonald;Mary W. Burney;Stuart B. Resnick;Herbert W. Virgin

  • Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks.

    William M. Schneider;Joseph M. Luna;H.-Heinrich Hoffmann;Francisco J. Sánchez-Rivera

Frequent Co-Authors

Charles M. Rice
Charles M. Rice Rockefeller University
Michel C. Nussenzweig
Michel C. Nussenzweig Rockefeller University
Davide F. Robbiani
Davide F. Robbiani Universita della Svizzera Italiana
John T. Poirier
John T. Poirier New York University Langone Medical Center
Koen K. A. Van Rompay
Koen K. A. Van Rompay University of California, Davis
Anna Gazumyan
Anna Gazumyan Rockefeller University
Emmanuelle Jouanguy
Emmanuelle Jouanguy Necker-Enfants Malades Hospital
Mitermayer G. Reis
Mitermayer G. Reis Oswaldo Cruz Foundation
Pamela J. Bjorkman
Pamela J. Bjorkman California Institute of Technology

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