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Biology and Biochemistry

D-Index
57
Citations
16268
World Ranking
13605
National Ranking
5772

Overview

John T. Poirier is affiliated with New York University Langone Medical Center in the United States. The scientist has contributed extensively to medical research, with a particular focus on molecular biology, oncology, and pulmonary and respiratory medicine. Their research spans several subfields, including epidemiology and infectious diseases.

Their recent publication record includes notable papers published between 2020 and 2021. These papers cover topics such as lung cancer metastasis, small cell lung cancer (SCLC) subtypes, host factor networks for coronaviruses, and cancer cell plasticity. Key publications include:

  • Regenerative lineages and immune-mediated pruning in lung cancer metastasis, 2020, Nature Medicine
  • SCLC Subtypes Defined by ASCL1, NEUROD1, POU2F3, and YAP1: A Comprehensive Immunohistochemical and Histopathologic Characterization, 2020, Journal of Thoracic Oncology
  • Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks, 2020, Cell
  • Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer, 2021, Cancer Cell
  • Emergence of a High-Plasticity Cell State during Lung Cancer Evolution, 2020, Cancer Cell

The scientist's work is frequently published in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Thoracic Oncology
  • Cancer Research
  • Cancer Cell
  • Journal of Clinical Oncology

John T. Poirier has collaborated regularly with several researchers, including Charles M. Rudin, Triparna Sen, Elisa de Stanchina, Kwok-Kin Wong, and Charles M. Rice.

Their primary fields of study are Medicine and Biochemistry, Genetics and Molecular Biology. Within these, more specific subfields include Molecular Biology, Oncology, Pulmonary and Respiratory Medicine, Epidemiology, and Infectious Diseases.

Research topics covered by John T. Poirier include:

  • Lung Cancer Research Studies
  • Neuroendocrine Tumor Research Advances
  • Lung Cancer Treatments and Mutations
  • RNA modifications and cancer
  • CRISPR and Genetic Engineering
  • SARS-CoV-2 and COVID-19 Research
  • Cancer Immunotherapy and Biomarkers

Best Publications

  • Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

    Charles M Rudin;Steffen Durinck;Eric W Stawiski;John T Poirier

  • Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data.

    Charles M. Rudin;John T. Poirier;Lauren Averett Byers;Caroline Dive

  • RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer

    Matthew J. Niederst;Lecia V. Sequist;John T. Poirier;Craig H. Mermel

  • A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo

    Laura R. Saunders;Alexander J. Bankovich;Wade C. Anderson;Monette A. Aujay

  • Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis.

    Rodrigo Romero;Volkan I Sayin;Shawn M Davidson;Matthew R Bauer

  • Friedreich's ataxia: Point mutations and clinical presentation of compound heterozygotes

    Mireille Cossée;A Dürr;M. Schmitt;N Dahl

  • Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis

    Eric E. Gardner;Eric E. Gardner;Benjamin H. Lok;Valentina E. Schneeberger;Patrice Desmeules

  • Next-Generation Sequencing of Pulmonary Large Cell Neuroendocrine Carcinoma Reveals Small Cell Carcinoma–like and Non–Small Cell Carcinoma–like Subsets

    Natasha Rekhtman;Maria C. Pietanza;Matthew D. Hellmann;Jarushka Naidoo

  • Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks.

    William M. Schneider;Joseph M. Luna;H.-Heinrich Hoffmann;Francisco J. Sánchez-Rivera

  • CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer

    Kipp Weiskopf;Nadine S. Jahchan;Peter J. Schnorr;Sandra Cristea

  • Unravelling the biology of SCLC: implications for therapy

    Joshua K. Sabari;Benjamin H. Lok;James H. Laird;John T. Poirier

  • A combinatorial strategy for treating KRAS-mutant lung cancer

    Eusebio Manchado;Susann Weissmueller;Susann Weissmueller;John P. Morris;Chi Chao Chen;Chi Chao Chen

  • SCLC Subtypes Defined by ASCL1, NEUROD1, POU2F3, and YAP1: A Comprehensive Immunohistochemical and Histopathologic Characterization

    Marina K Baine;Min-Shu Hsieh;W. Victoria Lai;Jacklynn V. Egger

  • Regenerative lineages and immune-mediated pruning in lung cancer metastasis

    Ashley M. Laughney;Jing Hu;Nathaniel R. Campbell;Nathaniel R. Campbell;Samuel F. Bakhoum

  • NK cell–mediated cytotoxicity contributes to tumor control by a cytostatic drug combination

    Marcus Ruscetti;Josef Leibold;Matthew J. Bott;Myles Fennell

  • PARP Inhibitor Activity Correlates with SLFN11 Expression and Demonstrates Synergy with Temozolomide in Small Cell Lung Cancer.

    Benjamin H. Lok;Eric E. Gardner;Eric E. Gardner;Valentina E. Schneeberger;Andy Ni

  • Emergence of a High-Plasticity Cell State during Lung Cancer Evolution

    Nemanja Despot Marjanovic;Nemanja Despot Marjanovic;Matan Hofree;Jason E. Chan;David Canner

  • Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer

    Joseph M. Chan;Álvaro Quintanal-Villalonga;Vianne Ran Gao;Vianne Ran Gao;Yubin Xie;Yubin Xie

  • DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2

    J T Poirier;E E Gardner;E E Gardner;N Connis;A L Moreira

  • Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks.

    William M. Schneider;Joseph M. Luna;H.-Heinrich Hoffmann;Francisco J. Sánchez-Rivera

Frequent Co-Authors

Charles M. Rudin
Charles M. Rudin Memorial Sloan Kettering Cancer Center
Jason S. Lewis
Jason S. Lewis Memorial Sloan Kettering Cancer Center
Natasha Rekhtman
Natasha Rekhtman Memorial Sloan Kettering Cancer Center
Scott W. Lowe
Scott W. Lowe Memorial Sloan Kettering Cancer Center
Charles M. Rice
Charles M. Rice Rockefeller University
Margaret R. MacDonald
Margaret R. MacDonald Rockefeller University
Matthew D. Hellmann
Matthew D. Hellmann Memorial Sloan Kettering Cancer Center
Pierre P. Massion
Pierre P. Massion Vanderbilt University Medical Center
Brian M. Zeglis
Brian M. Zeglis Hunter College

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