His primary scientific interests are in Virology, Immunology, Hepatitis C virus, Virus and Humanized mouse. As part of his studies on Virology, he often connects relevant subjects like Antibody. His Immune system, Viral pathogenesis and Interferon study in the realm of Immunology connects with subjects such as Infectious disease.
His work deals with themes such as Cell culture, Viral replication and Hepatitis C, which intersect with Hepatitis C virus. The Virus study which covers Antigen that intersects with Glycoprotein complex, Viral envelope and T cell. He usually deals with Hepacivirus and limits it to topics linked to Hepatocellular carcinoma and Chronic infection.
His scientific interests lie mostly in Virology, Immunology, Hepatitis C virus, Virus and Immune system. His Virology study integrates concerns from other disciplines, such as Humanized mouse, Cell culture and Antibody. His biological study spans a wide range of topics, including Hepatocellular carcinoma and Transgene.
His study in the fields of Hepacivirus under the domain of Hepatitis C virus overlaps with other disciplines such as Occludin. His work deals with themes such as Hepatitis B and Interferon, which intersect with Virus. His research in Immune system intersects with topics in Human leukocyte antigen and Cell biology.
Virology, Virus, Immune system, Viral entry and Hepatitis C virus are his primary areas of study. His study ties his expertise on Hepatitis E virus together with the subject of Virology. His research on Immune system concerns the broader Immunology.
His study in the field of Yellow fever vaccine and Immunization is also linked to topics like Treatment options and Opioid abuse. His Viral entry study integrates concerns from other disciplines, such as Viral envelope, Lipid bilayer fusion and Syncytium. Alexander Ploss has researched Hepatitis C virus in several fields, including Chronic infection, Hepatocyte and Cyclophilin A.
Alexander Ploss focuses on Virology, Immunity, Virus, Immune system and Immunology. His study in Virology focuses on Hepatitis B virus in particular. In his research, Innate immune system is intimately related to Interferon, which falls under the overarching field of Immunity.
His Virus research integrates issues from RNA, Subgenomic mRNA, Genome and Transcription. The study incorporates disciplines such as Myeloid, Viral pathogenesis, Transcriptome and Yellow fever vaccine in addition to Immune system. He is studying Viral infection, which is a component of Immunology.
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Human occludin is a hepatitis C virus entry factor required for infection of mouse cells
Alexander Ploss;Matthew J. Evans;Matthew J. Evans;Valeriya A. Gaysinskaya;Maryline Panis.
Nature (2009)
Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro
Brett D. Lindenbach;Philip Meuleman;Alexander Ploss;Thomas Vanwolleghem.
Proceedings of the National Academy of Sciences of the United States of America (2006)
HIV therapy by a combination of broadly neutralizing antibodies in humanized mice
Florian Klein;Ariel Halper-Stromberg;Joshua A. Horwitz;Henning Gruell;Henning Gruell.
Nature (2012)
A genetically humanized mouse model for hepatitis C virus infection
Marcus Dorner;Joshua A. Horwitz;Justin B. Robbins;Walter T. Barry.
Nature (2011)
A humanized mouse model to study hepatitis C virus infection, immune response, and liver disease.
Michael L. Washburn;Moses T. Bility;Liguo Zhang;Liguo Zhang;Grigoriy I. Kovalev.
Gastroenterology (2011)
The Yellow Fever Virus Vaccine Induces a Broad and Polyfunctional Human Memory CD8+ T Cell Response
Rama S. Akondy;Nathan D. Monson;Joseph D. Miller;Srilatha Edupuganti.
Journal of Immunology (2009)
Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus
Erick Giang;Marcus Dorner;Jannick C. Prentoe;Marlène Dreux;Marlène Dreux.
Proceedings of the National Academy of Sciences of the United States of America (2012)
Development of human CD4+FoxP3+ regulatory T cells in human stem cell factor–, granulocyte-macrophage colony-stimulating factor–, and interleukin-3–expressing NOD-SCID IL2Rγnull humanized mice
Eva K. Billerbeck;Walter T. Barry;Kathy Mu;Marcus Dorner.
Blood (2011)
Priming of protective T cell responses against virus-induced tumors in mice with human immune system components.
Till Strowig;Cagan Gurer;Alexander Ploss;Yi-Fang Liu.
Journal of Experimental Medicine (2009)
AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges
Matthew R. Gardner;Lisa M. Kattenhorn;Hema R. Kondur;Markus von Schaewen.
Nature (2015)
Journal of Hepatology
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