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Immunology

D-Index
56
Citations
13719
World Ranking
3693
National Ranking
1702

Overview

Alexander Ploss is affiliated with Princeton University in the United States and has contributed extensively to medical research, particularly in the study of viral infections related to hepatitis and other infectious diseases. Their research centers on various aspects of virology and immunology with a strong focus on hepatitis B virus (HBV) and hepatitis C virus (HCV) studies.

Their publication record includes several recent papers, notable for their contributions to understanding viral mechanisms and host interactions. These include:

  • SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation, 2021, eLife
  • μMap-Red: Proximity Labeling by Red Light Photocatalysis, 2022, Journal of the American Chemical Society
  • Mechanism of Hepatitis B Virus cccDNA Formation, 2021, Viruses
  • Core components of DNA lagging strand synthesis machinery are essential for hepatitis B virus cccDNA formation, 2020, Nature Microbiology
  • Hepatitis B virus cccDNA is formed through distinct repair processes of each strand, 2021, Nature Communications

Frequent co-authors collaborating with Alexander Ploss include:

  • Thomas R. Cafiero
  • Florian Douam
  • Nicholas A. Crossland
  • Brigitte Heller
  • Hans P. Gertje

Alexander Ploss publishes regularly in several scientific venues. The most frequent publication venues are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Viruses
  • mBio
  • Journal of Hepatology

Their main fields of study are situated within Medicine, with a pronounced focus on epidemiology, hepatology, molecular biology, infectious diseases, and immunology. Subfields of study include:

  • Epidemiology
  • Hepatology
  • Molecular Biology
  • Infectious Diseases
  • Immunology

Alexander Ploss's research explores key topics such as:

  • Hepatitis B Virus Studies
  • Hepatitis C virus research
  • Liver Disease Diagnosis and Treatment
  • Hepatitis Viruses Studies and Epidemiology
  • Interferon and immune responses
  • Viral gastroenteritis research and epidemiology
  • Mosquito-borne diseases and control

Best Publications

  • Human occludin is a hepatitis C virus entry factor required for infection of mouse cells

    Alexander Ploss;Matthew J. Evans;Matthew J. Evans;Valeriya A. Gaysinskaya;Maryline Panis

  • HIV therapy by a combination of broadly neutralizing antibodies in humanized mice

    Florian Klein;Ariel Halper-Stromberg;Joshua A. Horwitz;Henning Gruell;Henning Gruell

  • Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro

    Brett D. Lindenbach;Philip Meuleman;Alexander Ploss;Thomas Vanwolleghem

  • Decoding type I and III interferon signalling during viral infection.

    Emily V. Mesev;Robert A. LeDesma;Alexander Ploss

  • A genetically humanized mouse model for hepatitis C virus infection

    Marcus Dorner;Joshua A. Horwitz;Justin B. Robbins;Walter T. Barry

  • The Yellow Fever Virus Vaccine Induces a Broad and Polyfunctional Human Memory CD8+ T Cell Response

    Rama S. Akondy;Nathan D. Monson;Joseph D. Miller;Srilatha Edupuganti

  • Development of human CD4+FoxP3+ regulatory T cells in human stem cell factor–, granulocyte-macrophage colony-stimulating factor–, and interleukin-3–expressing NOD-SCID IL2Rγnull humanized mice

    Eva K. Billerbeck;Walter T. Barry;Kathy Mu;Marcus Dorner

  • Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus

    Erick Giang;Marcus Dorner;Jannick C. Prentoe;Marlène Dreux;Marlène Dreux

  • AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges

    Matthew R. Gardner;Lisa M. Kattenhorn;Hema R. Kondur;Markus von Schaewen

  • A humanized mouse model to study hepatitis C virus infection, immune response, and liver disease.

    Michael L. Washburn;Moses T. Bility;Liguo Zhang;Liguo Zhang;Grigoriy I. Kovalev

  • Hepatitis E virus: advances and challenges.

    Ila Nimgaonkar;Qiang Ding;Robert E. Schwartz;Alexander Ploss

  • Priming of protective T cell responses against virus-induced tumors in mice with human immune system components.

    Till Strowig;Cagan Gurer;Alexander Ploss;Yi-Fang Liu

  • HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice

    Joshua A. Horwitz;Ariel Halper-Stromberg;Hugo Mouquet;Alexander D. Gitlin

  • Real-time imaging of hepatitis C virus infection using a fluorescent cell-based reporter system

    Christopher T Jones;Maria Teresa Catanese;Lok Man J Law;Salman R Khetani

  • Complete Plasmodium falciparum liver-stage development in liver-chimeric mice

    Ashley M. Vaughan;Sebastian A. Mikolajczak;Elizabeth M. Wilson;Markus Grompe

  • Completion of the entire hepatitis C virus life cycle in genetically humanized mice

    Marcus Dorner;Joshua A. Horwitz;Bridget M. Donovan;Rachael N. Labitt

  • Humanized mice for modeling human infectious disease: challenges, progress, and outlook.

    Nicolas Legrand;Nicolas Legrand;Alexander Ploss;Alexander Ploss;Rudi Balling;Pablo D. Becker

  • Modeling hepatitis C virus infection using human induced pluripotent stem cells

    Robert E. Schwartz;Kartik Trehan;Linda Andrus;Timothy P. Sheahan

  • Broadly neutralizing antibodies abrogate established hepatitis C virus infection

    Ype P. de Jong;Ype P. de Jong;Marcus Dorner;Michiel C. Mommersteeg;Jing W. Xiao

  • Hepatitis E virus ORF3 is a functional ion channel required for release of infectious particles.

    Qiang Ding;Brigitte Heller;Juan M. V. Capuccino;Bokai Song

  • Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures

    Alexander Ploss;Salman R. Khetani;Christopher T. Jones;Andrew J. Syder

Frequent Co-Authors

Charles M. Rice
Charles M. Rice Rockefeller University
Michel C. Nussenzweig
Michel C. Nussenzweig Rockefeller University
Robert E. Schwartz
Robert E. Schwartz Cornell University
John W. Schoggins
John W. Schoggins The University of Texas Southwestern Medical Center
Dennis R. Burton
Dennis R. Burton Scripps Research Institute
Timothy P. Sheahan
Timothy P. Sheahan University of North Carolina at Chapel Hill
Eric G. Pamer
Eric G. Pamer Memorial Sloan Kettering Cancer Center
Philip Meuleman
Philip Meuleman Ghent University
Thomas Pietschmann
Thomas Pietschmann Hannover Medical School

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