D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 105 Citations 111,880 224 World Ranking 3879 National Ranking 2201
Genetics D-index 107 Citations 113,002 230 World Ranking 354 National Ranking 182

Research.com Recognitions

Awards & Achievements

2016 - National Institutes of Health Director's Pioneer Award

2015 - Paul Marks Prize for Cancer Research, Memorial Sloan Kettering Cancer Center

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Cancer

The scientist’s investigation covers issues in Genetics, Chromatin, Epigenetics, Computational biology and Human genome. His study in Genome, Epigenomics, DNA methylation, Histone and Histone code falls within the category of Genetics. The study incorporates disciplines such as Polycomb-group proteins and Induced pluripotent stem cell in addition to Chromatin.

The concepts of his Epigenetics study are interwoven with issues in Transcription factor, Regulation of gene expression, Gene expression profiling and Cancer research. He has researched Computational biology in several fields, including Transcriptional noise, ENCODE and Peak calling. Within one scientific family, Bradley E. Bernstein focuses on topics pertaining to Epigenome under Human genome, and may sometimes address concerns connected to Epigenesis.

His most cited work include:

  • Model-based Analysis of ChIP-Seq (MACS) (8233 citations)
  • Model-based Analysis of ChIP-Seq (MACS) (8233 citations)
  • Comprehensive mapping of long-range interactions reveals folding principles of the human genome. (4920 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Chromatin, Genetics, Computational biology, Epigenetics and Cancer research. The various areas that Bradley E. Bernstein examines in his Chromatin study include Enhancer, Transcription factor, Histone and Cell biology. His study in Epigenomics, Regulation of gene expression, Gene, Histone code and Chromatin immunoprecipitation is carried out as part of his studies in Genetics.

The Computational biology study combines topics in areas such as Genome, Human genome, Genomics, DNA and ChIP-sequencing. His Epigenetics study deals with DNA methylation intersecting with CTCF. His study focuses on the intersection of Cancer research and fields such as Cell with connections in the field of RNA, RNA-Seq, Immune system and Oligodendroglioma.

He most often published in these fields:

  • Chromatin (84.29%)
  • Genetics (82.98%)
  • Computational biology (58.38%)

What were the highlights of his more recent work (between 2017-2021)?

  • Computational biology (58.38%)
  • Epigenetics (57.33%)
  • Cancer research (37.96%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Computational biology, Epigenetics, Cancer research, Chromatin and DNA methylation. His biological study spans a wide range of topics, including Cell and Genome, Gene, Cas9, ENCODE. He has included themes like Protein kinase B, Enhancer, Receptor tyrosine kinase, Genetic heterogeneity and PDGFRA in his Epigenetics study.

His Cancer research study combines topics from a wide range of disciplines, such as Carcinogenesis, Cancer, Wnt signaling pathway, Transcription factor and Druggability. Bradley E. Bernstein combines subjects such as Epigenome, Epigenomics, Histone and Cell biology with his study of Chromatin. His DNA methylation course of study focuses on CTCF and GiST.

Between 2017 and 2021, his most popular works were:

  • Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types. (362 citations)
  • Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types. (362 citations)
  • An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma (341 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Cancer

Cancer research, Computational biology, Regulation of gene expression, Gene and Epigenetics are his primary areas of study. Bradley E. Bernstein focuses mostly in the field of Cancer research, narrowing it down to topics relating to Cell and, in certain cases, RNA, Genotyping and Bone marrow. His work in Computational biology addresses subjects such as Epigenomics, which are connected to disciplines such as Genome regulation, ENCODE and Genome.

As part of one scientific family, Bradley E. Bernstein deals mainly with the area of Regulation of gene expression, narrowing it down to issues related to the Transcriptome, and often Wnt signaling pathway, Medulloblastoma, Genomics and Single-cell analysis. His Gene research is within the category of Genetics. His Epigenetics research is multidisciplinary, incorporating elements of CTCF, Oncogene, GiST and Kit oncogene.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Model-based Analysis of ChIP-Seq (MACS)

Yong Zhang;Tao Liu;Clifford A Meyer;Jérôme Eeckhoute.
Genome Biology (2008)

11964 Citations

Comprehensive mapping of long-range interactions reveals folding principles of the human genome.

Erez Lieberman-Aiden;Nynke L. van Berkum;Louise Williams;Maxim Imakaev.
Science (2009)

7106 Citations

A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells

Bradley E. Bernstein;Tarjei S. Mikkelsen;Tarjei S. Mikkelsen;Xiaohui Xie;Michael Kamal.
Cell (2006)

5696 Citations

Integrative analysis of 111 reference human epigenomes

Anshul Kundaje;Wouter Meuleman;Wouter Meuleman;Jason Ernst.
Nature (2015)

4957 Citations

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

Tarjei S. Mikkelsen;Manching Ku;Manching Ku;David B. Jaffe;Biju Issac;Biju Issac.
Nature (2007)

4578 Citations

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

Mitchell Guttman;Ido Amit;Manuel Garber;Courtney French.
Nature (2009)

4399 Citations

In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

Marius Wernig;Alexander Meissner;Ruth Foreman;Tobias Brambrink.
Nature (2007)

3407 Citations

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

Anoop Premswaroop Patel;I. Tirosh;J. J. Trombetta;Alexander Kann Shalek.
Science (2014)

3302 Citations

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

Ahmad M. Khalil;Mitchell Guttman;Maite Huarte;Manuel Garber.
Proceedings of the National Academy of Sciences of the United States of America (2009)

3066 Citations

Mapping and analysis of chromatin state dynamics in nine human cell types

Jason Ernst;Pouya Kheradpour;Pouya Kheradpour;Tarjei S. Mikkelsen;Noam Shoresh.
Nature (2011)

3022 Citations

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