2026 Tarjei S. Mikkelsen: Genetics Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Genetics	74	1914	1821	875	823	136	119596

Overview

Tarjei S. Mikkelsen is affiliated with Arsenal Biosciences in the United States, where their research spans multiple interconnected fields within the broader domains of biochemistry, genetics, molecular biology, and medicine. Their contributions focus primarily on molecular biology with significant attention to oncology and pulmonary and respiratory medicine.

Their work is particularly centered on topics including CRISPR and genetic engineering, CAR-T cell therapy research, neonatal respiratory health, and congenital diaphragmatic hernia studies. Additionally, they engage with single-cell and spatial transcriptomics, RNA and protein synthesis mechanisms, and research related to renal and associated cancers.

Mikkelsen has published extensively, with notable papers including:

Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing, 2020, Nature Biotechnology
Progenitor identification and SARS-CoV-2 infection in human distal lung organoids, 2020, Nature
Integrated pseudotime analysis of human pre-implantation embryo single-cell transcriptomes reveals the dynamics of lineage specification, 2021, Cell Stem Cell
Progenitor identification and SARS-CoV-2 infection in long-term human distal lung organoid cultures, 2020, bioRxiv (Cold Spring Harbor Laboratory)
332 CRISPR/Cas9-based integration of a large and modular cassette into a safe harbor site to improve CAR T cell therapy efficacy and safety, 2022, Regular and Young Investigator Award Abstracts

Their research outputs have appeared frequently in various scientific venues such as Cancer Research, bioRxiv (Cold Spring Harbor Laboratory), Regular and Young Investigator Award Abstracts, UNC Libraries, and Nature Biotechnology.

Collaboration features prominently in Mikkelsen's work, with frequent co-authors including Jessica M. Terry, Aaron Cooper, Grace Zheng, Vincent C. Luca, and Phillip Belgrader. These collaborations highlight interdisciplinary approaches and multi-author efforts to address complex biomedical research questions.

Tarjei S. Mikkelsen's research integrates advanced genetic technologies and cellular biology methods, with a notable emphasis on CRISPR-based techniques and CAR-T cell therapies. Their work also addresses respiratory diseases and developmental biology using single-cell analysis and organoid models, reflecting the broad relevance and application of their research themes.

Best Publications

Initial sequencing and analysis of the human genome.

Eric S. Lander;Lauren M. Linton;Bruce Birren;Chad Nusbaum

31093
Citations
Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

Ophir Shalem;Ophir Shalem;Neville E Sanjana;Neville E Sanjana;Ella Hartenian;Xi-Shun Shi

12959
Citations
A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells

Bradley E. Bernstein;Tarjei S. Mikkelsen;Tarjei S. Mikkelsen;Xiaohui Xie;Michael Kamal

6355
Citations
Massively parallel digital transcriptional profiling of single cells

Grace X. Y. Zheng;Jessica M. Terry;Phillip Belgrader;Paul Ryvkin

5676
Citations
The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

Cole Trapnell;Davide Cacchiarelli;Davide Cacchiarelli;Jonna L Grimsby;Prapti Pokharel

5642
Citations
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

Tarjei S. Mikkelsen;Manching Ku;Manching Ku;David B. Jaffe;Biju Issac;Biju Issac

4951
Citations
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

Mitchell Guttman;Ido Amit;Manuel Garber;Courtney French

4722
Citations
The ENCODE (ENCyclopedia of DNA elements) Project

E. A. Feingold;P. J. Good;M. S. Guyer;S. Kamholz

3299
Citations
Mapping and analysis of chromatin state dynamics in nine human cell types

Jason Ernst;Pouya Kheradpour;Pouya Kheradpour;Tarjei S. Mikkelsen;Noam Shoresh

3290
Citations
Genome sequence, comparative analysis and haplotype structure of the domestic dog

Kerstin Lindblad-Toh;Claire M Wade;Claire M Wade;Tarjei S. Mikkelsen;Tarjei S. Mikkelsen;Elinor K. Karlsson;Elinor K. Karlsson

3074
Citations
Genome-scale DNA methylation maps of pluripotent and differentiated cells

Alexander Meissner;Tarjei S. Mikkelsen;Tarjei S. Mikkelsen;Hongcang Gu;Marius Wernig

2932
Citations
An integrated encyclopedia of DNA elements in the human genome

Ian Dunham;Anshul Kundaje;Shelley F. Aldred;Patrick J. Collins

2824
Citations
Initial sequence of the chimpanzee genome and comparison with the human genome

Tarjei S. Mikkelsen;LaDeana W. Hillier

2328
Citations
The NIH Roadmap Epigenomics Mapping Consortium

Bradley E Bernstein;John A Stamatoyannopoulos;Joseph F Costello;Bing Ren

1860
Citations
Dissecting direct reprogramming through integrative genomic analysis

Tarjei S. Mikkelsen;Jacob Hanna;Xiaolan Zhang;Manching Ku

1810
Citations
A User's Guide to the Encyclopedia of DNA Elements (ENCODE)

Richard M. Myers;John Stamatoyannopoulos;Michael Snyder;Ian Dunham

1560
Citations
Positive Natural Selection in the Human Lineage

P. C. Sabeti;S. F. Schaffner;B. Fry;J. Lohmueller

1342
Citations
Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains

Manching Ku;Richard P. Koche;Richard P. Koche;Richard P. Koche;Esther Rheinbay;Esther Rheinbay;Esther Rheinbay;Eric M. Mendenhall;Eric M. Mendenhall

1183
Citations
Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites

Schraga Schwartz;Maxwell R. Mumbach;Marko Jovanovic;Tim Wang;Tim Wang

1133
Citations
A unique regulatory phase of DNA methylation in the early mammalian embryo

Zachary D. Smith;Michelle M. Chan;Michelle M. Chan;Tarjei Sigurd Mikkelsen;Tarjei Sigurd Mikkelsen;Hongcang Gu

1076
Citations

Frequent Co-Authors

Eric S. Lander Broad Institute

Bradley E. Bernstein Broad Institute

Alexander Meissner Max Planck Institute for Molecular Genetics

Manolis Kellis MIT

Andreas Gnirke Broad Institute

John L. Rinn University of Colorado Boulder

Kerstin Lindblad-Toh Uppsala University

Evan D. Rosen Beth Israel Deaconess Medical Center

Pardis C. Sabeti Harvard University

Hongcang Gu Hefei Institutes of Physical Science

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