World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
48
Citations
22890
World Ranking
4021
National Ranking
103

Overview

Hongcang Gu is affiliated with the Hefei Institutes of Physical Science in China. Their research primarily focuses on the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Within these broader fields, they have contributed notably to subfields including Molecular Biology, Genetics, Cancer Research, Oncology, and Epidemiology.

The scientist's work covers a range of topics mainly centered on Epigenetics and DNA Methylation. Additional focus areas include Cancer Genomics and Diagnostics, RNA modifications and cancer, Mycobacterium research and diagnosis, Genetic Syndromes and Imprinting, Cancer Diagnosis and Treatment, and Congenital heart defects research.

Hongcang Gu has coauthored publications with several frequent collaborators. These include Yunfei Wang, Alexander Meissner, Jiantao Shi, Xiaoxue Wang, and Shutao He. Collaboration patterns show repeated joint contributions, with the highest number involving Yunfei Wang.

Their research has been disseminated in multiple peer-reviewed venues. Notable frequent publication venues include Nature Communications, Theranostics, Frontiers in Microbiology, Journal of Clinical Oncology, and UNC Libraries.

Key recent papers by Hongcang Gu or with their participation include:

  • Differential DNA methylation of vocal and facial anatomy genes in modern humans, 2020, Nature Communications
  • Smart-RRBS for single-cell methylome and transcriptome analysis, 2021, Nature Protocols
  • Technologies and applications of single-cell DNA methylation sequencing, 2023, Theranostics
  • DNA methylation profiling to determine the primary sites of metastatic cancers using formalin-fixed paraffin-embedded tissues, 2023, Nature Communications
  • Disorders Associated With Diverse, Recurrent Deletions and Duplications at 1q21.1, 2020, Frontiers in Genetics

Best Publications

  • Genome-scale DNA methylation maps of pluripotent and differentiated cells

    Alexander Meissner;Tarjei S. Mikkelsen;Tarjei S. Mikkelsen;Hongcang Gu;Marius Wernig

  • Charting a dynamic DNA methylation landscape of the human genome

    Michael J. Ziller;Hongcang Gu;Fabian Müller;Julie Donaghey;Julie Donaghey

  • Paternally Induced Transgenerational Environmental Reprogramming of Metabolic Gene Expression in Mammals

    Benjamin R. Carone;Lucas Fauquier;Naomi Habib;Jeremy M. Shea

  • Dnmt3a is essential for hematopoietic stem cell differentiation.

    Grant A. Challen;Deqiang Sun;Mira Jeong;Min Luo

  • Reference Maps of Human ES and iPS Cell Variation Enable High-Throughput Characterization of Pluripotent Cell Lines

    Christoph Bock;Evangelos Kiskinis;Evangelos Kiskinis;Griet Verstappen;Griet Verstappen;Hongcang Gu

  • A unique regulatory phase of DNA methylation in the early mammalian embryo

    Zachary D. Smith;Michelle M. Chan;Michelle M. Chan;Tarjei Sigurd Mikkelsen;Tarjei Sigurd Mikkelsen;Hongcang Gu

  • Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling

    Hongcang Gu;Zachary D Smith;Zachary D Smith;Christoph Bock;Patrick Boyle

  • Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications

    R Alan Harris;Ting Wang;Cristian Coarfa;Raman P. Nagarajan

  • Epigenomic Profiling of Young and Aged HSCs Reveals Concerted Changes during Aging that Reinforce Self-Renewal

    Deqiang Sun;Min Luo;Mira Jeong;Benjamin Rodriguez

  • Quantitative comparison of genome-wide DNA methylation mapping technologies

    Christoph Bock;Eleni M Tomazou;Eleni M Tomazou;Arie B Brinkman;Fabian Müller

  • DNA methylation signatures link prenatal famine exposure to growth and metabolism

    Elmar W. Tobi;Jelle J. Goeman;Ramin Monajemi;Hongcang Gu

  • Cellular Source and Mechanisms of High Transcriptome Complexity in the Mammalian Testis

    Magali Soumillon;Magali Soumillon;Anamaria Necsulea;Anamaria Necsulea;Manuela Weier;David Brawand;David Brawand

  • Targeted disruption of DNMT1 , DNMT3A and DNMT3B in human embryonic stem cells

    Jing Liao;Rahul Karnik;Hongcang Gu;Michael J Ziller

  • Proliferation-Dependent Alterations of the DNA Methylation Landscape Underlie Hematopoietic Stem Cell Aging

    Isabel Eleanor Beerman;Christoph Bock;Christoph Bock;Brian Scott Garrison;Brian Scott Garrison;Zachary D. Smith;Zachary D. Smith

  • Transcriptional and epigenetic dynamics during specification of human embryonic stem cells.

    Casey A. Gifford;Michael Johannes Ziller;Michael Johannes Ziller;Hongcang Gu;Cole Trapnell;Cole Trapnell

  • Genomic distribution and inter-sample variation of non-CpG methylation across human cell types.

    Michael J. Ziller;Fabian Müller;Jing Liao;Jing Liao;Yingying Zhang;Yingying Zhang

  • Reprogramming factor expression initiates widespread targeted chromatin remodeling.

    Richard P. Koche;Zachary D. Smith;Zachary D. Smith;Mazhar Adli;Mazhar Adli;Hongcang Gu

  • Sequential ChIP-bisulfite sequencing enables direct genome-scale investigation of chromatin and DNA methylation cross-talk

    Arie B. Brinkman;Hongcang Gu;Stefanie J.J. Bartels;Yingying Zhang

  • DNA methylation dynamics during in vivo differentiation of blood and skin stem cells.

    Christoph Bock;Isabel Beerman;Isabel Beerman;Wen-Hui Lien;Zachary D. Smith;Zachary D. Smith

  • Locally Disordered Methylation Forms the Basis of Intratumor Methylome Variation in Chronic Lymphocytic Leukemia

    Dan Avi Landau;Dan Avi Landau;Kendell Clement;Kendell Clement;Kendell Clement;Michael Johannes Ziller;Michael Johannes Ziller;Patrick Boyle

Frequent Co-Authors

Alexander Meissner
Alexander Meissner Max Planck Institute for Molecular Genetics
Andreas Gnirke
Andreas Gnirke Broad Institute
Christoph Bock
Christoph Bock Austrian Academy of Sciences
Bradley E. Bernstein
Bradley E. Bernstein Broad Institute
Tarjei S. Mikkelsen
Tarjei S. Mikkelsen Arsenal Biosciences (United States)
Catherine J. Wu
Catherine J. Wu Harvard University
David Reich
David Reich Harvard Medical School
Eric S. Lander
Eric S. Lander Broad Institute
John L. Rinn
John L. Rinn University of Colorado Boulder
Swapan Mallick
Swapan Mallick Harvard Medical School

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Genetics in the USA opens doors to several complementary online degrees and healthcare pathways. Many students explore programs related to medical administration, billing, and nursing to enhance job prospects or broaden their healthcare expertise.

For students interested in the administrative side of healthcare, pursuing a healthcare administration degree online can lead to roles such as hospital manager, health information specialist, or clinical supervisor. Those seeking the most affordable route into this field might consider the cheapest online healthcare management degree programs, which can lower costs while building vital leadership skills.

Alternatively, students interested in direct patient interaction may want to research what nursing programs are easy to get into. Entry-level nursing degrees offer a practical way to enter the healthcare workforce, with flexible online options available.

For those looking for non-clinical and in-demand roles, obtaining a medical billing certification can provide job security in medical records and billing departments. These paths allow Genetics students to diversify their expertise and expand future career opportunities in healthcare.

Best Scientists Citing Hongcang Gu

Trending Scientists

Recently Published Articles