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D-Index & Metrics

Genetics

D-Index
74
Citations
21100
World Ranking
1965
National Ranking
246

Overview

Gavin Kelsey is affiliated with the Babraham Institute in the United Kingdom and has a research portfolio focused primarily on biochemistry, genetics, and molecular biology, with significant contributions to medicine as well. Their work spans several subfields including molecular biology, genetics, pediatrics, perinatology, child health, public health, environmental and occupational health, and reproductive medicine.

The scientist's research topics encompass a range of areas with an emphasis on epigenetics and DNA methylation, genetic syndromes and imprinting, reproductive biology and fertility, prenatal screening and diagnostics, birth, development, and health, single-cell and spatial transcriptomics, and genomics and chromatin dynamics.

Gavin Kelsey has published extensively, contributing to multiple scientific venues. Frequent publication outlets include:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Clinical Epigenetics
  • International Journal of Molecular Sciences
  • Human Reproduction

Recent papers authored or co-authored by Gavin Kelsey include:

  • DNA methylation changes during preimplantation development reveal inter-species differences and reprogramming events at imprinted genes, 2020, Clinical Epigenetics
  • A distinctive epigenetic ageing profile in human granulosa cells, 2020, Human Reproduction
  • Sex-specific chromatin remodelling safeguards transcription in germ cells, 2021, Nature
  • Features and mechanisms of canonical and noncanonical genomic imprinting, 2021, Genes & Development
  • Increased transcriptome variation and localised DNA methylation changes in oocytes from aged mice revealed by parallel single-cell analysis, 2020, Aging Cell

Their collaborative network includes several frequent co-authors, notably António Galvão, Elena V. Ivanova, Juan Castillo-Fernandez, Simon Andrews, and Courtney W. Hanna, with co-authorship counts ranging from 8 to 23 joint publications.

Best Publications

  • Placental-specific IGF-II is a major modulator of placental and fetal growth

    Miguel Constância;Myriam Hemberger;Jennifer Hughes;Wendy Dean

  • Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity

    Sébastien A Smallwood;Heather J Lee;Heather J Lee;Christof Angermueller;Felix Krueger

  • Dynamic CpG island methylation landscape in oocytes and preimplantation embryos

    Sébastien A Smallwood;Shin-ichi Tomizawa;Felix Krueger;Nico Ruf

  • Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity

    Christof Angermueller;Stephen J Clark;Heather J Lee;Heather J Lee;Iain C Macaulay

  • scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells.

    Stephen James Clark;Ricardo Argelaguet;Chantriolnt-Andreas Kapourani;Thomas M Stubbs

  • Genomic Imprinting and Physiological Processes in Mammals.

    Valter Tucci;Anthony R. Isles;Gavin Kelsey;Gavin Kelsey;Anne C. Ferguson-Smith

  • De novo DNA methylation: a germ cell perspective

    Sébastien A. Smallwood;Gavin Kelsey

  • Multi-omics profiling of mouse gastrulation at single-cell resolution.

    Ricard Argelaguet;Stephen J. Clark;Hisham Mohammed;L. Carine Stapel

  • Single-cell epigenomics: Recording the past and predicting the future

    Gavin Kelsey;Gavin Kelsey;Oliver Stegle;Wolf Reik;Wolf Reik;Wolf Reik

  • Transactivation of Igf2 in a mouse model of Beckwith–Wiedemann syndrome

    Fang-Lin Sun;Wendy L. Dean;Gavin Kelsey;Nicholas D. Allen

  • A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice

    Andreas Schedl;Lluís Montoliu;Gavin Kelsey;Günther Schütz

  • Transcription is required for establishment of germline methylation marks at imprinted genes

    Mita Chotalia;Sebastien A. Smallwood;Nico Ruf;Claire Dawson

  • Adaptation of nutrient supply to fetal demand in the mouse involves interaction between the Igf2 gene and placental transporter systems

    Miguel Constância;Emily Angiolini;Ionel Sandovici;Paul Smith

  • The imprinted signaling protein XL alpha s is required for postnatal adaptation to feeding.

    Antonius Plagge;Emma Gordon;Wendy Dean;Romina Boiani

  • Limited evolutionary conservation of imprinting in the human placenta

    D. Monk;P. Arnaud;S. Apostolidou;F. A. Hills

  • miR-29a and miR-29b Contribute to Pancreatic β-Cell-Specific Silencing of Monocarboxylate Transporter 1 (Mct1)

    Timothy J. Pullen;Gabriela da Silva Xavier;Gavin Kelsey;Gavin Kelsey;Guy A. Rutter

  • Single-cell epigenomics: powerful new methods for understanding gene regulation and cell identity

    Stephen James Clark;Heather J Lee;Heather J Lee;Sébastien A Smallwood;Sébastien A Smallwood;Gavin Kelsey;Gavin Kelsey

  • Resourceful imprinting : Fertility

    Miguel Constancia;Gavin Kelsey;Wolf Relk

  • A cluster of oppositely imprinted transcripts at the Gnas locus in the distal imprinting region of mouse chromosome 2

    Jo Peters;Stephanie F. Wroe;Christine A. Wells;Howard J. Miller

  • Epigenetic analysis of the Dlk1–Gtl2 imprinted domain on mouse chromosome 12: implications for imprinting control from comparison with Igf2–H19

    Shuji Takada;Martina Paulsen;Maxine Tevendale;Chen-En Tsai

Frequent Co-Authors

Wolf Reik
Wolf Reik Babraham Institute
Wendy Dean
Wendy Dean Babraham Institute
Simon Andrews
Simon Andrews Babraham Institute
Andreas Schedl
Andreas Schedl Grenoble Alpes University
John C. Marioni
John C. Marioni European Bioinformatics Institute
Oliver Stegle
Oliver Stegle German Cancer Research Center
robert feil
robert feil Centre national de la recherche scientifique, CNRS
Günther Schütz
Günther Schütz German Cancer Research Center
Philip Stanier
Philip Stanier University College London
Anne C. Ferguson-Smith
Anne C. Ferguson-Smith University of Cambridge

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