Alfred G. Gilman

Research.com Recognitions

• 1994 - Nobel Prize for their discovery of G-proteins and the role of these proteins in signal transduction in cells
• 1989 - Fellow of the American Association for the Advancement of Science (AAAS)
• 1985 - Member of the National Academy of Sciences
• 1964 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

  Alfred G. Gilman

  8655
  Citations

• A Protein Binding Assay for Adenosine 3′:5′-Cyclic Monophosphate

  Alfred G. Gilman

  4778
  Citations

• G proteins and dual control of adenylate cyclase

  Alfred G. Gilman

  2444
  Citations

• Type-Specific Regulation of Adenylyl Cyclase by G Protein βγ Subunits

  Wei Jen Tang;Alfred G. Gilman

  1579
  Citations

• The structure of the G protein heterotrimer Giα1β1γ2

  Mark A. Wall;David E. Coleman;Ethan Lee;Jorge A. Iñiguez-Lluhi

  1509
  Citations

• Biochemical properties of hormone-sensitive adenylate cyclase.

  E. M. Ross;A. G. Gilman

  1404
  Citations

• Crystal Structure of the Catalytic Domains of Adenylyl Cyclase in a Complex with Gsα·GTPγS

  John J. G. Tesmer;Roger K. Sunahara;Alfred G. Gilman;Stephen R. Sprang

  1149
  Citations

• Complexity and Diversity of Mammalian Adenylyl Cyclases

  Roger K. Sunahara;Carmen W. Dessauer;Alfred G. Gilman

  1142
  Citations

• Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis.

  David E. Coleman;Albert M. Berghuis;Ethan Lee;Maurine E. Linder

  1125
  Citations

• GAIP and RGS4 Are GTPase-Activating Proteins for the Gi Subfamily of G Protein α Subunits

  David M Berman;Thomas M Wilkie;Alfred G Gilman

  1112
  Citations

• p115 RhoGEF, a GTPase activating protein for Gα12 and Gα13

  Tohru Kozasa;Xuejun Jiang;Matthew J. Hart;Pamela M. Sternweis

  1093
  Citations

• Direct Stimulation of the Guanine Nucleotide Exchange Activity of p115 RhoGEF by Gα13

  Matthew J. Hart;Xuejun Jiang;Tohru Kozasa;William Roscoe

  1050
  Citations

• MAMMALIAN MEMBRANE-BOUND ADENYLYL CYCLASES

  Ronald Taussig;Alfred G. Gilman

  1046
  Citations

• Structure of RGS4 Bound to AlF4−-Activated Giα1: Stabilization of the Transition State for GTP Hydrolysis

  John J.G. Tesmer;David M. Berman;Alfred G. Gilman;Stephen R. Sprang

  1016
  Citations

• Protein kinase C phosphorylates the inhibitory guanine-nucleotide-binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclase.

  Toshiaki Katada;Alfred G. Gilman;Yasuhiro Watanabe;Silvia Bauer

  995
  Citations

• Adenylyl cyclase amino acid sequence: possible channel- or transporter-like structure.

  John Krupinski;Françoise Coussen;Françoise Coussen;Heather A. Bakalyar;Wei Jen Tang

  902
  Citations

• G proteins

  Unknown

  866
  Citations

• Aluminum: a requirement for activation of the regulatory component of adenylate cyclase by fluoride.

  Paul C. Sternweis;Alfred G. Gilman

  839
  Citations

• Cyclic Adenosine Monophosphate and Alteration of Chinese Hamster Ovary Cell Morphology: a Rapid, Sensitive In Vitro Assay for the Enterotoxins of Vibrio cholerae and Escherichia coli

  Richard L. Guerrant;Laurence L. Brunton;Terry C. Schnaitman;Lionel I. Rebhun

  829
  Citations

• G protein involvement in receptor-effector coupling.

  P J Casey;A G Gilman

  781
  Citations

• Identification of the predominant substrate for ADP-ribosylation by islet activating protein.

  G M Bokoch;T Katada;J K Northup;E L Hewlett

  773
  Citations