What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- G protein-coupled receptor
John K. Northup focuses on Biochemistry, Cyclase, Adenylate kinase, Cyclase activity and GTP'.
His study focuses on the intersection of Biochemistry and fields such as Molecular biology with connections in the field of Beta.
John K. Northup works mostly in the field of Cyclase, limiting it down to concerns involving Binding site and, occasionally, Guanosine triphosphate.
His Adenylate kinase research focuses on Molecular mass and how it relates to Sodium dodecyl sulfate.
His Cyclase activity research integrates issues from Biophysics, Endoplasmic reticulum and Cholera toxin.
John K. Northup regularly ties together related areas like GTP-binding protein regulators in his GTP' studies.
His most cited work include:
- Identification of the predominant substrate for ADP-ribosylation by islet activating protein. (495 citations)
- The guanine nucleotide activating site of the regulatory component of adenylate cyclase. Identification by ligand binding. (454 citations)
- The regulatory component of adenylate cyclase. Purification and properties. (429 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Biochemistry, G protein, Receptor, Molecular biology and G protein-coupled receptor.
All of his Biochemistry and Adenylate kinase, Cyclase, Guanine, GTP' and Heterotrimeric G protein investigations are sub-components of the entire Biochemistry study.
He works on Cyclase which deals in particular with Cyclase activity.
As part of one scientific family, John K. Northup deals mainly with the area of G protein, narrowing it down to issues related to the Rhodopsin, and often Phospholipid.
His studies deal with areas such as Amino acid and Extracellular as well as Receptor.
His Molecular biology research incorporates elements of Alpha, In vitro, Mutant, Peptide sequence and Beta.
He most often published in these fields:
- Biochemistry (75.34%)
- G protein (34.25%)
- Receptor (30.14%)
What were the highlights of his more recent work (between 2008-2018)?
- Biochemistry (75.34%)
- G protein-coupled receptor (21.92%)
- Heterotrimeric G protein (15.07%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Biochemistry, G protein-coupled receptor, Heterotrimeric G protein, G protein and Guanine.
His research in G protein-coupled receptor tackles topics such as Biophysics which are related to areas like Hydrolase, Allosteric regulation, Phospholipase C and Phospholipase.
His study in the fields of Gs alpha subunit and cAMP-dependent pathway under the domain of G protein overlaps with other disciplines such as Rhodopsin-like receptors.
His Guanine study is related to the wider topic of Nucleotide.
His Nucleotide study combines topics from a wide range of disciplines, such as Crystallography, GTP', ADP ribosylation factor and Phosphatidylcholine.
John K. Northup works mostly in the field of Phosphatidylcholine, limiting it down to topics relating to Rhodopsin and, in certain cases, POPC.
Between 2008 and 2018, his most popular works were:
- Modulation of the interaction between neurotensin receptor NTS1 and Gq protein by lipid. (90 citations)
- Gipc3 mutations associated with audiogenic seizures and sensorineural hearing loss in mouse and human (73 citations)
- An Autoinhibitory Helix in the C-Terminal Region of Phospholipase C-β Mediates Gαq Activation (57 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Enzyme
- G protein-coupled receptor
His main research concerns Gq alpha subunit, Biochemistry, Biophysics, G protein-coupled receptor and Neuroscience.
His Gq alpha subunit study integrates concerns from other disciplines, such as Phospholipase, Heterotrimeric G protein, Hydrolase and Phospholipase C.
John K. Northup incorporates Biochemistry and Neurotensin receptor in his studies.
The study incorporates disciplines such as Phospholipid and Allosteric regulation in addition to Biophysics.
His studies in Neuroscience integrate themes in fields like Sensorineural hearing loss, Missense mutation and Genetics.
His Spiral ganglion research is multidisciplinary, incorporating perspectives in Mutation, Mechanotransduction and Hair cell.
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