World's Best Scientists 2026 revealed!
Hideyuki Takeuchi

Hideyuki Takeuchi

D-Index & Metrics

Biology and Biochemistry

D-Index
75
Citations
16898
World Ranking
5417
National Ranking
350

Overview

Hideyuki Takeuchi is affiliated with Yokohama City University in Japan and has contributed extensively to the field of medicine, with a focus on neurology, surgery, pulmonary and respiratory medicine, molecular biology, and pathology and forensic medicine. Their publication record comprises 148 works in medicine, highlighting a multidisciplinary approach to clinical and biomedical research.

Their recent papers include:

  • Long-read sequencing identifies the pathogenic nucleotide repeat expansion in RFC1 in a Japanese case of CANVAS, 2020, published in Journal of Human Genetics
  • New Technique for Magnetic Compression Anastomosis Without Incision for Gastrointestinal Obstruction, 2020, published in Journal of the American College of Surgeons
  • CCR2 is localized in microglia and neurons, as well as infiltrating monocytes, in the lumbar spinal cord of ALS mice, 2020, published in Molecular Brain
  • De novo ATP1A3 variants cause polymicrogyria, 2021, published in Science Advances
  • Effectiveness and safety of tumor site marking with near-infrared fluorescent clips in colorectal laparoscopic surgery: A case series study, 2020, published in International Journal of Surgery

The scientist's primary research topics encompass esophageal and gastrointestinal pathology, multiple sclerosis research studies, gastric cancer management and outcomes, gastroesophageal reflux and treatments, peripheral neuropathies and disorders, amyotrophic lateral sclerosis research, and neuroinflammation and neurodegeneration mechanisms.

Frequent co-authors collaborating with Hideyuki Takeuchi include:

  • Fumiaki Tanaka
  • Hiroshi Doi
  • Keita Takahashi
  • Misako Kunii
  • Mikiko Tada

Publications are often featured in these venues:

  • Clinical and Experimental Neuroimmunology
  • Surgical Case Reports
  • Molecular Brain
  • Annals of Neurology
  • Annals of Medicine and Surgery

Takeuchi's work reflects an integration of clinical studies and experimental research, with particular attention to neurological disorders and surgical innovations. The distribution of publications across various subfields indicates an interdisciplinary approach, combining neurology and surgical techniques with molecular and pathological investigations.

Best Publications

  • Tumor Necrosis Factor-α Induces Neurotoxicity via Glutamate Release from Hemichannels of Activated Microglia in an Autocrine Manner

    Hideyuki Takeuchi;Shijie Jin;Jinyan Wang;Guiqin Zhang

  • Minocycline selectively inhibits M1 polarization of microglia

    K Kobayashi;S Imagama;T Ohgomori;K Hirano

  • Genome-wide association study using whole-genome sequencing rapidly identifies new genes influencing agronomic traits in rice

    Kenji Yano;Eiji Yamamoto;Koichiro Aya;Hideyuki Takeuchi

  • Long-read sequencing identifies GGC repeat expansions in NOTCH2NLC associated with neuronal intranuclear inclusion disease.

    Jun Sone;Satomi Mitsuhashi;Atsushi Fujita;Takeshi Mizuguchi

  • Neuritic beading induced by activated microglia is an early feature of neuronal dysfunction toward neuronal death by inhibition of mitochondrial respiration and axonal transport.

    Hideyuki Takeuchi;Tetsuya Mizuno;Guiqin Zhang;Jinyan Wang

  • Rumi Is a CAP10 Domain Glycosyltransferase that Modifies Notch and Is Required for Notch Signaling

    Melih Acar;Hamed Jafar-Nejad;Hideyuki Takeuchi;Akhila Rajan

  • Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis.

    Tsuyoshi Yoshihara;Shinsuke Ishigaki;Masahiko Yamamoto;Yideng Liang

  • Interleukin-1β induces blood-brain barrier disruption by downregulating Sonic hedgehog in astrocytes.

    Yue Wang;Shijie Jin;Yoshifumi Sonobe;Yi Cheng

  • Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis

    Yue-Mei Jiang;Masahiko Yamamoto;Yasushi Kobayashi;Tsuyoshi Yoshihara

  • Four-jointed is a Golgi kinase that phosphorylates a subset of cadherin domains.

    Hiroyuki O. Ishikawa;Hideyuki Takeuchi;Robert S. Haltiwanger;Kenneth D. Irvine

  • Production and functions of IL-17 in microglia

    Jun Kawanokuchi;Kouki Shimizu;Atsumi Nitta;Kiyofumi Yamada

  • Autocrine activation of microglia by tumor necrosis factor-α

    Reiko Kuno;Jinyan Wang;Jun Kawanokuchi;Hideyuki Takeuchi

  • Fingolimod phosphate promotes the neuroprotective effects of microglia

    Hiromi Noda;Hideyuki Takeuchi;Tetsuya Mizuno;Akio Suzumura

  • Production and functions of IL-33 in the central nervous system

    Satoko Yasuoka;Jun Kawanokuchi;Bijay Parajuli;Shijie Jin

  • Oligomeric amyloid β induces IL-1β processing via production of ROS: implication in Alzheimer's disease.

    B Parajuli;Y Sonobe;H Horiuchi;H Takeuchi

  • Interferon-gamma directly induces neurotoxicity through a neuron specific, calcium-permeable complex of IFN-gamma receptor and AMPA GluR1 receptor.

    Tetsuya Mizuno;Guiqin Zhang;Hideyuki Takeuchi;Jun Kawanokuchi

  • Regulation of mammalian Notch signaling and embryonic development by the protein O-glucosyltransferase Rumi

    Rodrigo Fernandez-Valdivia;Hideyuki Takeuchi;Amin Samarghandi;Mario Lopez

  • Production of interferon-γ by microglia

    J Kawanokuchi;T Mizuno;H Takeuchi;H Kato

  • Fractalkine Attenuates Excito-neurotoxicity via Microglial Clearance of Damaged Neurons and Antioxidant Enzyme Heme Oxygenase-1 Expression

    Mariko Noda;Yukiko Doi;Jianfeng Liang;Jun Kawanokuchi

  • GM-CSF increases LPS-induced production of proinflammatory mediators via upregulation of TLR4 and CD14 in murine microglia

    Bijay Parajuli;Yoshifumi Sonobe;Jun Kawanokuchi;Yukiko Doi

Frequent Co-Authors

Fumiaki Tanaka
Fumiaki Tanaka Yokohama City University
Tetsuya Mizuno
Tetsuya Mizuno Nagoya University
Gen Sobue
Gen Sobue Aichi Medical University
Naomichi Matsumoto
Naomichi Matsumoto Yokohama City University
Noriko Miyake
Noriko Miyake Yokohama City University
Hirotomo Saitsu
Hirotomo Saitsu Hamamatsu University
Martin C. Frith
Martin C. Frith University of Tokyo
Kenji Kadomatsu
Kenji Kadomatsu Nagoya University
Jun-ichi Kira
Jun-ichi Kira Kyushu University
Atsumi Nitta
Atsumi Nitta University of Toyama

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Biology and Biochemistry in the USA opens diverse pathways in healthcare, nutrition, research, and management. For those interested in advanced nursing roles, pursuing the shortest online nurse practitioner program can lead to faster entry into specialized patient care fields. This flexible option allows graduates to build on their science background and move quickly into practice.

Alternatively, online options like a dietitian degree online enable students to leverage their biochemistry knowledge in growing areas such as nutrition and dietetics. These programs are designed for those eager to impact public health through evidence-based dietary planning and counseling.

For those who are already registered nurses, there are rn to bsn online no clinicals options that help streamline your advancement in nursing, strengthen core scientific skills, and broaden career opportunities—all without additional clinical requirements.

Lastly, science graduates interested in leadership roles may consider the degree in healthcare management to swiftly prepare for administration or management positions in the healthcare industry.

Best Scientists Citing Hideyuki Takeuchi

Trending Scientists

Recently Published Articles