World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
113
Citations
39614
World Ranking
5013
National Ranking
192

Research.com Recognitions

  • 2017 - J. Allyn Taylor International Prize in Medicine, Robarts Research Institute
  • 2014 - Fellow of the Royal Society of Canada Academy of Science

Overview

V. Wee Yong is affiliated with the University of Calgary in Canada. Their research spans multiple fields including Medicine, Biochemistry, Genetics and Molecular Biology, and Neuroscience. Within these broader disciplines, specific subfields include Neurology, Molecular Biology, Immunology, Pathology and Forensic Medicine, and Epidemiology.

The scientist's research topics cover a range of neurological and immunological areas. Key themes include Intracerebral and Subarachnoid Hemorrhage Research, Multiple Sclerosis Research Studies, Neuroinflammation and Neurodegeneration Mechanisms, Neurogenesis and Neuroplasticity Mechanisms, Immune Cells in Cancer, Acute Ischemic Stroke Management, and Peripheral Neuropathies and Disorders.

V. Wee Yong has published extensively in notable journals. Frequent publication venues include bioRxiv (Cold Spring Harbor Laboratory), Journal of Neuroinflammation, Journal of Neurorestoratology, Frontiers in Immunology, and Multiple Sclerosis and Related Disorders.

Among the recent papers are:

  • Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy, 2020, Nature Communications
  • Multiple sclerosis progression: time for a new mechanism-driven framework, 2022, The Lancet Neurology
  • Neuroinflammation in intracerebral haemorrhage: immunotherapies with potential for translation, 2020, The Lancet Neurology
  • Microglia response following acute demyelination is heterogeneous and limits infiltrating macrophage dispersion, 2020, Science Advances
  • Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression, 2020, Nature Communications

Frequent co-authors in their work include Mengzhou Xue, Samira Ghorbani, Brian M. Lozinski, Reza Mirzaei, and Yifei Dong.

V. Wee Yong has been recognized with several awards including the J. Allyn Taylor International Prize in Medicine from the Robarts Research Institute in 2017, and election as a Fellow of the Royal Society of Canada in 2014 by the Academy of Science.

Best Publications

  • Metalloproteinases in biology and pathology of the nervous system

    V. Wee Yong;Christopher Power;Peter Forsyth;Dylan R. Edwards

  • Matrix metalloproteinases and diseases of the CNS.

    Voon Wee Yong;Peter A. Forsyth;Robert Bell;Craig A. Krekoski

  • Metalloproteinases: Mediators of Pathology and Regeneration in the CNS

    V. Wee Yong

  • Inefficient clearance of myelin debris by microglia impairs remyelinating processes

    Antoine Lampron;Antoine Larochelle;Nathalie Laflamme;Paul Préfontaine

  • The promise of minocycline in neurology

    V Wee Yong;Jennifer Wells;Fabrizio Giuliani;Steven Casha

  • Pro-regenerative properties of cytokine-activated astrocytes.

    Christina M. Liberto;P. J. Albrecht;L. M. Herx;V. W. Yong

  • Pathophysiology of the brain extracellular matrix: a new target for remyelination

    Lorraine W. Lau;Rowena Cua;Michael B. Keough;Sarah Haylock-Jacobs

  • Expanding antigen-specific regulatory networks to treat autoimmunity

    Xavier Clemente-Casares;Jesus Blanco;Jesus Blanco;Poornima Ambalavanan;Jun Yamanouchi

  • Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy

    Charles P. Couturier;Shamini Ayyadhury;Phuong U. Le;Javad Nadaf;Javad Nadaf

  • Targeting leukocyte MMPs and transmigration: minocycline as a potential therapy for multiple sclerosis.

    Veronika Brundula;N Barry Rewcastle;Luanne M Metz;Claude Charles Andre Bernard

  • Review: Endocrine disrupting chemicals and immune responses: A focus on bisphenol-A and its potential mechanisms

    James A. Rogers;Luanne Metz;V. Wee Yong

  • Neuroprotection by minocycline facilitates significant recovery from spinal cord injury in mice

    Jennifer E. A. Wells;R. John Hurlbert;Michael G. Fehlings;V. Wee Yong

  • Intracerebral hemorrhage induces macrophage activation and matrix metalloproteinases

    Christopher Power;Scot Henry;Marc R. Del Bigio;Peter H. Larsen

  • Interferon beta in the treatment of multiple sclerosis Mechanisms of action

    V. Wee Yong;Sophie Chabot;Olaf Stuve;Gary Williams

  • Human endogenous retrovirus glycoprotein-mediated induction of redox reactants causes oligodendrocyte death and demyelination.

    Joseph M Antony;Guido van Marle;Wycliffe Opii;D Allan Butterfield

  • CXCR4 Is a Major Chemokine Receptor on Glioma Cells and Mediates Their Survival

    Yan Zhou;Peter H. Larsen;Chunhai Hao;V. Wee Yong

  • Analyses of all matrix metalloproteinase members in leukocytes emphasize monocytes as major inflammatory mediators in multiple sclerosis

    Amit Bar-Or;Robert K. Nuttall;Martin Duddy;Andrea Alter

  • Interferon β-1b decreases the migration of T lymphocytes in vitro: Effects on matrix metalloproteinase-9

    Olaf Stüve;Nora P. Dooley;Joon H. Uhm;Jack P. Antel

  • Reactive astrogliosis in the neonatal mouse brain and its modulation by cytokines

    Vijayabalan Balasingam;Trevor Tejada-Berges;Erin Wright;Radka Bouckova

  • Results of a phase II placebo-controlled randomized trial of minocycline in acute spinal cord injury

    Steven Casha;David Zygun;M. Dan McGowan;Ish Bains

Frequent Co-Authors

Peter K. Stys
Peter K. Stys University of Calgary
Serge Rivest
Serge Rivest Université Laval
Dylan R. Edwards
Dylan R. Edwards University of East Anglia
Stephen M. Robbins
Stephen M. Robbins University of Calgary
Samuel Weiss
Samuel Weiss University of Calgary
Christopher Power
Christopher Power University of Alberta
Jeff Dunn
Jeff Dunn University of Southern Queensland
Jack P. Antel
Jack P. Antel McGill University
Amit Bar-Or
Amit Bar-Or University of Pennsylvania
Wolfram Tetzlaff
Wolfram Tetzlaff University of British Columbia

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