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Neuroscience

D-Index
70
Citations
17509
World Ranking
2514
National Ranking
139

Research.com Recognitions

  • 2013 - Fellow of the Royal Society of Canada Academy of Science

Overview

Peter K. Stys is affiliated with the University of Calgary in Canada. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a significant focus on molecular biology, neurology, physiology, pathology and forensic medicine, and epidemiology.

Their scholarly work concentrates on key topics such as Alzheimer's disease research and treatments, prion diseases and protein misfolding, acute ischemic stroke management, neuroinflammation and neurodegeneration mechanisms, multiple sclerosis research studies, stroke rehabilitation and recovery, and RNA regulation and disease.

Frequent collaborators in their research include Michael D. Hill, Eric E. Smith, Shelagh B. Coutts, Philip A. Barber, and Megan L. Morgan.

Peter K. Stys has published frequently in various scientific journals, including:

  • Journal of Alzheimer s Disease
  • JAMA Network Open
  • Journal of Neurochemistry
  • Molecular Brain
  • ACS Chemical Neuroscience

Significant recent papers authored or co-authored by Peter K. Stys include:

  • Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial, 2020, The Lancet
  • Microglia response following acute demyelination is heterogeneous and limits infiltrating macrophage dispersion, 2020, Science Advances
  • Ferroptosis Mediates Cuprizone-Induced Loss of Oligodendrocytes and Demyelination, 2020, Journal of Neuroscience
  • Plasma Neurofilament Light: A Marker of Neurodegeneration in Mild Behavioral Impairment, 2020, Journal of Alzheimer s Disease
  • Nile Red fluorescence spectroscopy reports early physicochemical changes in myelin with high sensitivity, 2021, Proceedings of the National Academy of Sciences

In recognition of their scientific contributions, Peter K. Stys was named a Fellow of the Royal Society of Canada in 2013 by the Academy of Science.

Best Publications

  • Ionic mechanisms of anoxic injury in mammalian CNS white matter: role of Na+ channels and Na(+)-Ca2+ exchanger

    Peter K. Stys;Stephen G. Waxman;Bruce R. Ransom

  • Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis

    Bruce D Trapp;Peter K Stys

  • Inefficient clearance of myelin debris by microglia impairs remyelinating processes

    Antoine Lampron;Antoine Larochelle;Nathalie Laflamme;Paul Préfontaine

  • Will the real multiple sclerosis please stand up

    Peter K. Stys;Gerald W. Zamponi;Jan van Minnen;Jeroen J. G. Geurts

  • Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial.

    Michael D Hill;Mayank Goyal;Bijoy K Menon;Raul G Nogueira

  • NMDA receptors mediate calcium accumulation in myelin during chemical ischaemia.

    I. Micu;Q. Jiang;E. Coderre;A. Ridsdale

  • Traumatic axonal injury induces calcium influx modulated by tetrodotoxin-sensitive sodium channels.

    John A. Wolf;Peter K. Stys;Theresa Lusardi;David Meaney

  • Anoxic and ischemic injury of myelinated axons in CNS white matter: from mechanistic concepts to therapeutics.

    Peter K. Stys

  • Mechanisms of Ionotropic Glutamate Receptor-Mediated Excitotoxicity in Isolated Spinal Cord White Matter

    Shuxin Li;Peter K. Stys

  • General mechanisms of axonal damage and its prevention

    Peter K. Stys

  • White matter injury mechanisms.

    Peter K Stys

  • Novel Injury Mechanism in Anoxia and Trauma of Spinal Cord White Matter: Glutamate Release via Reverse Na+-dependent Glutamate Transport

    Shuxin Li;Geoff A. R. Mealing;Paul Morley;Peter K. Stys

  • Second asymptomatic carotid surgery trial (ACST-2): a randomised comparison of carotid artery stenting versus carotid endarterectomy

    Alison Halliday;Richard Bulbulia;Leo H Bonati;Johanna Chester

  • Aβ neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-d-aspartate receptors

    Haitao You;Shigeki Tsutsui;Shahid Hameed;Thomas J. Kannanayakal

  • Traumatic Axonal Injury Induces Proteolytic Cleavage of the Voltage-Gated Sodium Channels Modulated by Tetrodotoxin and Protease Inhibitors

    Akira Iwata;Peter K. Stys;John A. Wolf;Xiao-Han Chen

  • Immunosenescence of microglia and macrophages: impact on the ageing central nervous system

    Khalil S. Rawji;Manoj K. Mishra;Nathan J. Michaels;Serge Rivest

  • Noninactivating, tetrodotoxin-sensitive Na+ conductance in rat optic nerve axons

    Peter K. Stys;Harald Sontheimer;Harald Sontheimer;Bruce R. Ransom;Stephen G. Waxman;Stephen G. Waxman

  • Na+‐Ca2+ exchanger mediates Ca2+ influx during anoxia in mammalian central nervous system white matter

    Peter K. Stys;Stephen G. Waxman;Bruce R. Ransom

  • Role of extracellular calcium in anoxic injury of mammalian central white matter.

    Peter K. Stys;Bruce R. Ransom;Stephen G. Waxman;Peter K. Davis

  • Compound action potential of nerve recorded by suction electrode: a theoretical and experimental analysis.

    Peter K. Stys;Bruce R. Ransom;Bruce R. Ransom;Stephen G. Waxman;Stephen G. Waxman

  • Erratum: Will the real multiple sclerosis please stand up? (Nature Reviews Neuroscience (2012) 13 (507-514))

    Peter K. Stys;Gerald W. Zamponi;Jan van Minnen;Jeroen J. G. Geurts

Frequent Co-Authors

Stephen G. Waxman
Stephen G. Waxman Yale University
Gerald W. Zamponi
Gerald W. Zamponi University of Calgary
Bruce R. Ransom
Bruce R. Ransom University of Washington
Jeroen J. G. Geurts
Jeroen J. G. Geurts Vrije Universiteit Amsterdam
Stuart A. Lipton
Stuart A. Lipton Scripps Research Institute
Zahinoor Ismail
Zahinoor Ismail University of Calgary
Sulayman D. Dib-Hajj
Sulayman D. Dib-Hajj Yale University
Theodore R. Cummins
Theodore R. Cummins Indiana University – Purdue University Indianapolis
John A. Wolf
John A. Wolf University of Pennsylvania
Joel A. Black
Joel A. Black Yale University

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