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Biology and Biochemistry

D-Index
47
Citations
7737
World Ranking
18725
National Ranking
865

Overview

Anne Caignard is affiliated with Grenoble Alpes University in France, focusing on research at the intersection of medicine, immunology, and oncology. Their work encompasses multiple subfields including immunology, molecular biology, hematology, and surgery.

Their research covers several main topics, notably:

  • Immune Cell Function and Interaction
  • CAR-T cell therapy research
  • Acute Myeloid Leukemia Research
  • Epigenetics and DNA Methylation
  • IL-33, ST2, and ILC Pathways
  • Eosinophilic Esophagitis
  • Melanoma and MAPK Pathways

Anne Caignard has contributed to a number of publications across various well-regarded scientific journals. Recent papers include:

  • Myelodysplastic Syndrome associated TET2 mutations affect NK cell function and genome methylation, 2023, Nature Communications
  • BRAF inhibitor resistance of melanoma cells triggers increased susceptibility to natural killer cell-mediated lysis, 2020, Journal for ImmunoTherapy of Cancer
  • Specific Patterns of Blood ILCs in Metastatic Melanoma Patients and Their Modulations in Response to Immunotherapy, 2021, Cancers
  • The impact of COVID-19 lock-downs for European (female) immunologists - our views as members of the EFIS gender and diversity task force, 2020, European Journal of Immunology
  • Hépatite sévère induite par ipilimumab plus nivolumab traitée par photochimiothérapie extracorporelle: premier cas, 2020, Annales de Dermatologie et de Vénéréologie

Their work has appeared most frequently in the following publication venues:

  • European Journal of Immunology
  • Nature Communications
  • Cancers
  • Journal for ImmunoTherapy of Cancer
  • Annales de Dermatologie et de Vénéréologie

Anne Caignard collaborates regularly with several co-authors, including:

  • Louise Rethacker
  • Nicolas Dulphy
  • Antoine Toubert
  • E. Maubec
  • Maxime Boy

Their body of work involves exploring immune mechanisms, particularly natural killer cell function and interactions, as well as resistance mechanisms in melanoma and immunotherapy responses. They have also engaged in research on the effects of epigenetic alterations in hematological conditions. This combination of diverse expertise positions them within interdisciplinary biomedical research focused on both fundamental and clinical questions related to immune responses and cancer biology.

Best Publications

  • Classification of current anticancer immunotherapies

    Lorenzo Galluzzi;Erika Vacchelli;José Manuel Bravo-San Pedro;Aitziber Buqué

  • The host—tumor immune conflict: from immunosuppression to resistance and destruction

    Salem Chouaib;Carine Asselin-Paturel;Fathia Mami-Chouaib;Anne Caignard

  • An experimentally validated panel of subfamily‐specific oligonucleotide primers (Vα1‐w29/Vβ1‐w24) for the study of human T cell receptor variable V gene segment usage by polymerase chain reaction

    Catherine Genevée;Anita Diu;Janine Nierat;Anne Caignard

  • NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs

    Christophe Borg;Abdelali Jalil;Diego Laderach;Kouji Maruyama

  • Immune infiltrates are prognostic factors in localized gastrointestinal stromal tumors

    Sylvie Rusakiewicz;Michaela Semeraro;Matthieu Sarabi;Mélanie Desbois

  • Phosphostim-Activated γδ T Cells Kill Autologous Metastatic Renal Cell Carcinoma

    Emilie Viey;Gaëlle Fromont;Bernard Escudier;Yannis Morel

  • Selection by trypsin of two sublines of rat colon cancer cells forming progressive or regressive tumors

    François Martin;Anne Caignard;Jean‐François Jeannin;Annick Leclerc

  • Tumor-specific up-regulation of the nonclassical class I HLA-G antigen expression in renal carcinoma.

    El Chérif Ibrahim;Nadia Guerra;Marie-José Terrier Lacombe;Eric Angevin

  • Interaction between two cellular subpopulations of a rat colonic carcinoma when inoculated to the syngeneic host

    A. Caignard;M. S. Martin;M. F. Michel;F. Martin

  • Cytolytic function and survival of natural killer cells are severely altered in myelodysplastic syndromes

    Kiladjian Jj;Bourgeois E;Lobe I;Braun T

  • Consensus nomenclature for CD8+ T cell phenotypes in cancer

    Lionel Apetoh;Mark J. Smyth;Charles G. Drake;Jean Pierre Abastado

  • NK cells differentiated from bone marrow, cord blood and peripheral blood stem cells exhibit similar phenotype and functions

    Géraldine Carayol;Catherine Robin;Jean-Henri Bourhis;Annelise Bennaceur-Griscelli

  • In vivo T-cell clonal amplification at time of acute graft-versus-host disease

    PY Dietrich;A Caignard;A Lim;V Chung

  • Tumor-Derived Mesenchymal Stem Cells Use Distinct Mechanisms to Block the Activity of Natural Killer Cell Subsets

    Sabine Galland;Joanna Vuille;Patricia Martin;Igor Letovanec

  • Phenotypic and Functional Dysregulated Blood NK Cells in Colorectal Cancer Patients Can Be Activated by Cetuximab Plus IL-2 or IL-15.

    Yamila Rocca;Maria Paula Roberti;Estefanía Paula Juliá;María Betina Pampena

  • Mature Cytotoxic CD56bright/CD16+ Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma

    Meriem Messaoudene;Giulia Fregni;Emmanuelle Fourmentraux-Neves;Johan Chanal

  • Killer inhibitory receptor (CD158b) modulates the lytic activity of tumor-specific T lymphocytes infiltrating renal cell carcinomas.

    Nadia Guerra;Nadia Guerra;Maryvonne Guillard;Maryvonne Guillard;Eric Angevin;Eric Angevin;Hamid Echchakir;Hamid Echchakir

  • Quantitative analysis of T helper 1, T helper 2, and inflammatory cytokine expression in patients after allogeneic bone marrow transplantation: relationship with the occurrence of acute graft-versus-host disease.

    Géraldine Carayol;Jean Henri Bourhis;Maryvonne Guillard;Jacques Bosq

  • Phenotypic and Functional Characteristics of Blood Natural Killer Cells from Melanoma Patients at Different Clinical Stages

    Giulia Fregni;Meriem Messaoudene;Emmanuelle Fourmentraux-Neves;Sarra Mazouz-Dorval

  • Serum Soluble HLA-E in Melanoma: A New Potential Immune-Related Marker in Cancer

    Mathilde Allard;Mathilde Allard;Romain Oger;Romain Oger;Virginie Vignard;Jean-Michel Percier

Frequent Co-Authors

Salem Chouaib
Salem Chouaib Gulf Medical University
Antoine Toubert
Antoine Toubert Université Paris Cité
Laurence Zitvogel
Laurence Zitvogel University of Paris-Saclay
Bernard Escudier
Bernard Escudier Institut Gustave Roussy
Marie-Françoise Avril
Marie-Françoise Avril Université Paris Cité
Guido Kroemer
Guido Kroemer Université Paris Cité
Fathia Mami-Chouaib
Fathia Mami-Chouaib Institut Gustave Roussy
Christophe Borg
Christophe Borg Centre Hospitalier Universitaire de Besançon
Alexander M.M. Eggermont
Alexander M.M. Eggermont Institut Gustave Roussy
Frédéric Triebel
Frédéric Triebel University of Paris-Saclay

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