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Karl-Johan Malmberg

Karl-Johan Malmberg

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Immunology
Norway
2026

D-Index & Metrics

Immunology

D-Index
71
Citations
18612
World Ranking
2312
National Ranking
12

Medicine

D-Index
71
Citations
18676
World Ranking
19988
National Ranking
108

Research.com Recognitions

  • 2026 - Research.com Immunology in Norway Leader Award
  • 2025 - Research.com Immunology in Norway Leader Award
  • 2022 - Research.com Immunology in Norway Leader Award

Overview

Karl-Johan Malmberg is affiliated with Oslo University Hospital in Norway and has contributed extensively to research in immunology and microbiology, with particular focus on immune cell function and interactions. Their work spans key areas such as CAR-T cell therapy, T-cell and B-cell immunology, immunotherapy, infectious diseases, oncology, and hematology.

The researcher has published frequently in respected venues including Blood, Regular and Young Investigator Award Abstracts, bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Immunology, and Science Immunology. Their collaborations include several frequent co-authors, reflecting an active network within the scientific community.

  • Ebba Sohlberg
  • Bahram Valamehr
  • Quirin Hammer
  • Eivind Heggernes Ask
  • Brian Groff

Karl-Johan Malmberg's recent notable publications cover vital topics around immune responses to infectious diseases and cancer immunology. Selected papers include:

  • "High-dimensional single-cell analysis of human natural killer cell heterogeneity," 2024, Nature Immunology
  • "Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19," 2020, Cell
  • "Natural killer cell immunotypes related to COVID-19 disease severity," 2020, Science Immunology
  • "Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity," 2020, Cell stem cell
  • "MAIT cell activation and dynamics associated with COVID-19 disease severity," 2020, Science Immunology

The main fields of study Karl-Johan Malmberg is involved in include:

  • Immunology and Microbiology
  • Medicine

Their work also delves deeper into subfields such as:

  • Immunology
  • Oncology
  • Molecular Biology
  • Infectious Diseases
  • Hematology

Key research topics addressed by Karl-Johan Malmberg are:

  • Immune Cell Function and Interaction
  • CAR-T cell therapy research
  • T-cell and B-cell Immunology
  • Immunotherapy and Immune Responses
  • COVID-19 Clinical Research Studies
  • Immune cells in cancer
  • Hematopoietic Stem Cell Transplantation

Best Publications

  • Intense metabolic control by means of insulin in patients with diabetes mellitus and acute myocardial infarction (DIGAMI 2): effects on mortality and morbidity

    K Malmberg;Lars Rydén;H Wedel;K Birkeland

  • Expression patterns of NKG2A, KIR, and CD57 define a process of CD56dim NK-cell differentiation uncoupled from NK-cell education

    Niklas K. Björkström;Peggy Riese;Frank Heuts;Sandra Andersson

  • Cytomegalovirus infection drives adaptive epigenetic diversification of NK cells with altered signaling and effector function.

    Heinrich Schlums;Frank M Cichocki;Frank M Cichocki;Bianca Tesi;Jakob Theorell

  • Prospects for the use of NK cells in immunotherapy of human cancer

    Hans-Gustaf Ljunggren;Karl-Johan Malmberg

  • NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRS

    Vivien Béziat;Lisa L. Liu;Jenny-Ann Malmberg;Martin A. Ivarsson

  • Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus

    Niklas K. Björkström;Therese Lindgren;Malin Stoltz;Cyril Fauriat;Cyril Fauriat

  • Natural killer cell immunotypes related to COVID-19 disease severity.

    Christopher Maucourant;Iva Filipovic;Andrea Ponzetta;Soo Aleman;Soo Aleman

  • Newly detected abnormal glucose tolerance: an important predictor of long-term outcome after myocardial infarction.

    M Bartnik;K Malmberg;A Norhammar;A Tenerz

  • Admission plasma glucose. Independent risk factor for long-term prognosis after myocardial infarction even in nondiabetic patients.

    A M Norhammar;L Rydén;K Malmberg

  • Education of human natural killer cells by activating killer cell immunoglobulin-like receptors

    Cyril Fauriat;Martin A. Ivarsson;Hans-Gustaf Ljunggren;Karl-Johan Malmberg

  • CMV drives clonal expansion of NKG2C+ NK cells expressing self-specific KIRs in chronic hepatitis patients.

    Vivien Béziat;Vivien Béziat;Vivien Béziat;Olav Dalgard;Tarik Asselah;Philippe Halfon

  • CD56bright NK cells exhibit potent antitumor responses following IL-15 priming.

    Julia A. Wagner;Maximillian Rosario;Rizwan Romee;Melissa M. Berrien-Elliott

  • Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity.

    Huang Zhu;Robert H. Blum;Davide Bernareggi;Eivind Heggernes Ask

  • Primary human tumor cells expressing CD155 impair tumor targeting by down-regulating DNAM-1 on NK cells.

    Mattias Carlsten;Håkan Norell;Yenan T. Bryceson;Isabel Poschke

  • DNAX Accessory Molecule-1 Mediated Recognition of Freshly Isolated Ovarian Carcinoma by Resting Natural Killer Cells

    Mattias Carlsten;Niklas K. Björkström;Håkan Norell;Yenan Bryceson

  • Natural killer cell-mediated immunosurveillance of human cancer.

    Karl-Johan Malmberg;Mattias Carlsten;Andreas Björklund;Ebba Sohlberg

  • Diabetes mellitus and congestive heart failure. Further knowledge needed.

    L. Soläng;K. Malmberg;L. Rydén

  • IFN-γ protects short-term ovarian carcinoma cell lines from CTL lysis via a CD94/NKG2A-dependent mechanism

    Karl Johan Malmberg;Victor Levitsky;Håkan Norell;Cristina Teixeira De Matos

  • Role for early-differentiated natural killer cells in infectious mononucleosis

    Tarik Azzi;Tarik Azzi;Anna Lünemann;Anna Lünemann;Anita Murer;Seigo Ueda;Seigo Ueda;Seigo Ueda

  • Critical Role of CD2 Co-stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C- Deficient Humans

    Lisa L. Liu;Johannes Landskron;Eivind H. Ask;Eivind H. Ask;Monika Enqvist

  • Identification of new HER2/neu-derived peptide epitopes that can elicit specific CTL against autologous and allogeneic carcinomas and melanomas.

    Yang Rongcun;Flavio Salazar-Onfray;Jehad Charo;Karl Johan Malmberg

Frequent Co-Authors

Hans-Gustaf Ljunggren
Hans-Gustaf Ljunggren Karolinska Institute
Niklas K. Björkström
Niklas K. Björkström Karolinska University Hospital
Jeffrey S. Miller
Jeffrey S. Miller University of Minnesota
Jakob Michaëlsson
Jakob Michaëlsson Karolinska University Hospital
Dan S. Kaufman
Dan S. Kaufman University of California, San Diego
Rolf Kiessling
Rolf Kiessling Karolinska Institute
Yenan T. Bryceson
Yenan T. Bryceson Karolinska Institute
Johan K. Sandberg
Johan K. Sandberg Karolinska University Hospital
Per Ljungman
Per Ljungman Karolinska University Hospital

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