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Biology and Biochemistry

D-Index
63
Citations
14488
World Ranking
10205
National Ranking
4455

Overview

Dan S. Kaufman is affiliated with the University of California, San Diego in the United States. Their research primarily focuses on immunology and microbiology, medicine, and biochemistry, genetics, and molecular biology. Within these domains, their work often addresses specific subfields such as immunology, oncology, molecular biology, hematology, and physiology.

The scientist has contributed extensively to topics including CAR-T cell therapy research, immune cell function and interaction, T-cell and B-cell immunology, CRISPR and genetic engineering, pluripotent stem cells research, immune cells in cancer, and phagocytosis and immune regulation.

Recent papers by Dan S. Kaufman include the following:

  • Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity, 2020, Cell Stem Cell
  • iPSC-derived NK cells maintain high cytotoxicity and enhance in vivo tumor control in concert with T cells and anti-PD-1 therapy, 2020, Science Translational Medicine
  • iPSC-Derived Natural Killer Cell Therapies - Expansion and Targeting, 2022, Frontiers in Immunology
  • CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity, 2022, Nature Communications
  • Induced pluripotent stem cell-derived engineered T cells, natural killer cells, macrophages, and dendritic cells in immunotherapy, 2023, Trends in Biotechnology

Frequent co-authors of Dan S. Kaufman include:

  • Davide Bernareggi
  • Benjamin Goldenson
  • Jaya Lakshmi Thangaraj
  • Max Schabla
  • Manuel Fierro

The scientist's work has been published in various venues with multiple contributions in prominent journals such as Cancer Research, Blood, Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, bioRxiv (Cold Spring Harbor Laboratory), and Cell Stem Cell.

Best Publications

  • Multilineage differentiation from human embryonic stem cell lines.

    Jon S. Odorico;Dan S. Kaufman;James A. Thomson

  • Hematopoietic colony-forming cells derived from human embryonic stem cells

    Dan S. Kaufman;Eric T. Hanson;Rachel L. Lewis;Robert Auerbach

  • Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity.

    Ye Li;David L. Hermanson;Branden S. Moriarity;Dan S. Kaufman

  • Cardiac Repair in a Porcine Model of Acute Myocardial Infarction with Human Induced Pluripotent Stem Cell-Derived Cardiovascular Cells

    Lei Ye;Ying Hua Chang;Qiang Xiong;Pengyuan Zhang

  • Clinical-Scale Derivation of Natural Killer Cells From Human Pluripotent Stem Cells for Cancer Therapy

    David A. Knorr;Zhenya Ni;David L Lampi Hermanson;Melinda K. Hexum

  • Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity.

    Huang Zhu;Robert H. Blum;Davide Bernareggi;Eivind Heggernes Ask

  • Human embryonic stem cells differentiate into a homogeneous population of natural killer cells with potent in vivo antitumor activity.

    Petter S. Woll;Bartosz Grzywacz;Xinghui Tian;Rebecca K. Marcus

  • Efficient transfection of embryonic and adult stem cells.

    Uma Lakshmipathy;Beatriz Pelacho;Kazuhiro Sudo;Jonathan L. Linehan

  • Pluripotent stem cell-derived NK cells with high-affinity noncleavable CD16a mediate improved antitumor activity.

    Huang Zhu;Robert H. Blum;Ryan Bjordahl;Svetlana Gaidarova

  • Human Embryonic Stem Cell-Derived NK Cells Acquire Functional Receptors and Cytolytic Activity

    Petter S. Woll;Colin H. Martin;Jeffrey S. Miller;Dan S. Kaufman

  • Induced Pluripotent Stem Cell-Derived Natural Killer Cells for Treatment of Ovarian Cancer.

    David L. Hermanson;Laura Bendzick;Lee Pribyl;Valarie McCullar

  • Wnt signaling promotes hematoendothelial cell development from human embryonic stem cells

    Petter S. Woll;Julie K. Morris;Matt S. Painschab;Rebecca K. Marcus

  • Improved development of human embryonic stem cell-derived embryoid bodies by stirred vessel cultivation.

    C. M. Cameron;Wei Shou Hu;Dan S. Kaufman

  • Hematopoietic engraftment of human embryonic stem cell-derived cells is regulated by recipient innate immunity.

    Xinghui Tian;Petter S. Woll;Julie K. Morris;Jonathan L. Linehan

  • An expanded universe of cancer targets.

    William C. Hahn;Joel S. Bader;Theodore P. Braun;Andrea Califano

  • Utilizing chimeric antigen receptors to direct natural killer cell activity.

    David L Lampi Hermanson;Dan S Kaufman

  • Toward clinical therapies using hematopoietic cells derived from human pluripotent stem cells

    Dan S. Kaufman

  • Hematopoietisk differentiering av humana embryonala stamceller

    Kaufman Dan S;Thomson James A

  • iPSC-derived NK cells maintain high cytotoxicity and enhance in vivo tumor control in concert with T cells and anti-PD-1 therapy.

    Frank Cichocki;Ryan Bjordahl;Svetlana Gaidarova;Sajid Mahmood

  • Differentiation of human embryonic stem cells into hematopoietic cells by coculture with human fetal liver cells recapitulates the globin switch that occurs early in development.

    Caihong Qiu;Eric Hanson;Emmanuel Olivier;Mari Inada

Frequent Co-Authors

Jeffrey S. Miller
Jeffrey S. Miller University of Minnesota
Karl-Johan Malmberg
Karl-Johan Malmberg Oslo University Hospital
James A. Thomson
James A. Thomson University of California, Santa Barbara
Bruce Walcheck
Bruce Walcheck University of Minnesota
Robert Auerbach
Robert Auerbach University of Wisconsin–Madison
Bruce R. Blazar
Bruce R. Blazar University of Minnesota
Thomas H. Lee
Thomas H. Lee Harvard University
Daniel J. Weisdorf
Daniel J. Weisdorf University of Minnesota
Michael R. Verneris
Michael R. Verneris University of Colorado Denver
R. Scott McIvor
R. Scott McIvor University of Minnesota

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