World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
8444
World Ranking
16813
National Ranking
6937

Overview

R. Scott McIvor is affiliated with the University of Minnesota in the United States and has contributed extensively to research in Medicine and Biochemistry, Genetics, and Molecular Biology. Their scholarly output covers a broad range of specialized topics within these fields.

The scientist's main fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these fields, McIvor has focused on several subfields, including:

  • Physiology
  • Genetics
  • Oncology
  • Molecular Biology
  • Immunology

Key topics of research addressed by McIvor encompass:

  • Lysosomal Storage Disorders Research
  • CAR-T cell therapy research
  • Virus-based gene therapy research
  • Trypanosoma species research and implications
  • CRISPR and Genetic Engineering
  • Neurogenetic and Muscular Disorders Research
  • Immune Cell Function and Interaction

The scientist has published regularly in specific venues, with frequent appearances in:

  • Molecular Genetics and Metabolism
  • Human Gene Therapy
  • International Journal of Molecular Sciences
  • Molecular Genetics and Metabolism Reports
  • bioRxiv (Cold Spring Harbor Laboratory)

Collaborations with fellow researchers are a notable aspect of McIvor's career. Frequent co-authors include:

  • Lalitha R. Belur (16 joint works)
  • Miles C. Smith (13 joint works)
  • Troy C. Lund (12 joint works)
  • Beau R. Webber (12 joint works)
  • Branden S. Moriarity (12 joint works)

Among recent publications, several reflect McIvor's focus on gene therapy, immunology, and metabolic disorders:

  • Mucopolysaccharidosis Type I: A Review of the Natural History and Molecular Pathology, 2020, Cells
  • Mucopolysaccharidosis Type I: Current Treatments, Limitations, and Prospects for Improvement, 2021, Biomolecules
  • Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade, 2022, Med
  • Lentiviral Gene Therapy for Artemis-Deficient SCID, 2022, New England Journal of Medicine
  • Treatment of cerebral adrenoleukodystrophy: allogeneic transplantation and lentiviral gene therapy, 2022, Expert Opinion on Biological Therapy

Best Publications

  • Sarcoma derived from cultured mesenchymal stem cells

    Jakub Tolar;Alma J. Nauta;Mark J. Osborn;Angela Panoskaltsis Mortari

  • Harnessing a high cargo-capacity transposon for genetic applications in vertebrates.

    Darius Balciunas;Kirk J Wangensteen;Andrew Wilber;Jason Bell

  • Facilitated transport of uracil and 5‐fluorouracil, and permeation of orotic acid into cultured mammalian cells

    R. M. Wohlhueter;R. S. McIvor;P. G W Plagemann

  • Biodistribution of adeno-associated virus serotype 9 (AAV9) vector after intrathecal and intravenous delivery in mouse

    Daniel J. Schuster;Jaclyn A. Dykstra;Maureen S. Riedl;Kelley F. Kitto

  • Phenotypic correction and long-term expression of factor VIII in hemophilic mice by immunotolerization and nonviral gene transfer using the Sleeping Beauty transposon system

    John R. Ohlfest;Joel L. Frandsen;Sabine Fritz;Paul D. Lobitz

  • The Sleeping Beauty transposon system: a non-viral vector for gene therapy

    Elena L. Aronovich;R. Scott McIvor;Perry B. Hackett

  • Preferential delivery of the Sleeping Beauty transposon system to livers of mice by hydrodynamic injection

    Jason B Bell;Kelly M Podetz-Pedersen;Elena L Aronovich;Lalitha R Belur

  • Somatic integration of an oncogene-harboring Sleeping Beauty transposon models liver tumor development in the mouse

    Corey M. Carlson;Joel L. Frandsen;Nicole Kirchhof;R. Scott McIvor

  • Sleeping Beauty Transposon‐Mediated Gene Therapy for Prolonged Expression

    Perry B. Hackett;Stephen C. Ekker;David A. Largaespada;R. Scott McIvor

  • Sleeping Beauty Transposon‐mediated Engineering of Human Primary T Cells for Therapy of CD19+ Lymphoid Malignancies

    Xin Huang;Hongfeng Guo;Johnthomas Kang;Suet Choi

  • An ex vivo gene therapy approach to treat muscular dystrophy using inducible pluripotent stem cells

    Antonio Filareto;Sarah Parker;Radbod Darabi;Luciene Borges

  • Efficient and Stable Transgene Expression in Human Embryonic Stem Cells Using Transposon‐Mediated Gene Transfer

    Andrew Wilber;Jonathan L. Linehan;Xinghui Tian;Petter S. Woll

  • RNA as a Source of Transposase for Sleeping Beauty-Mediated Gene Insertion and Expression in Somatic Cells and Tissues

    Andrew Wilber;Joel L. Frandsen;Jennifer L. Geurts;David A. Largaespada

  • Prolonged expression of a lysosomal enzyme in mouse liver after Sleeping Beauty transposon-mediated gene delivery: implications for non-viral gene therapy of mucopolysaccharidoses.

    Elena L. Aronovich;Jason B. Bell;Lalitha R. Belur;Roland Gunther

  • Stable gene transfer and expression in human primary T cells by the Sleeping Beauty transposon system.

    Xin Huang;Andrew C. Wilber;Andrew C. Wilber;Lei Bao;Lei Bao;Dong Tuong;Dong Tuong

  • Gene insertion and long-term expression in lung mediated by the Sleeping Beauty transposon system.

    Lalitha R Belur;Joel L Frandsen;Adam J Dupuy;David H Ingbar

  • Correction of metabolic, craniofacial, and neurologic abnormalities in MPS I mice treated at birth with adeno-associated virus vector transducing the human α-l-iduronidase gene

    Seth D Hartung;Joel L Frandsen;Dao Pan;Brenda L Koniar

  • Human purine nucleoside phosphorylase and adenosine deaminase: gene transfer into cultured cells and murine hematopoietic stem cells by using recombinant amphotropic retroviruses.

    R S McIvor;M J Johnson;A D Miller;S Pitts

  • Stable gene transfer and expression in cord blood–derived CD34+ hematopoietic stem and progenitor cells by a hyperactive Sleeping Beauty transposon system

    Xingkui Xue;Xin Huang;Sonja E. Nodland;Lajos Mátés

  • Systemic Correction of Storage Disease in MPS I NOD/SCID Mice Using the Sleeping Beauty Transposon System

    Elena L Aronovich;Jason B Bell;Shaukat A Khan;Shaukat A Khan;Lalitha R Belur

Frequent Co-Authors

Perry B. Hackett
Perry B. Hackett University of Minnesota
David A. Largaespada
David A. Largaespada University of Minnesota
Bruce R. Blazar
Bruce R. Blazar University of Minnesota
Jakub Tolar
Jakub Tolar University of Minnesota
Paul J. Orchard
Paul J. Orchard University of Minnesota
Mark A. Kay
Mark A. Kay Stanford University
Stephen C. Ekker
Stephen C. Ekker Mayo Clinic
Michael C. Holmes
Michael C. Holmes Ambys Medicines
William H. Frey
William H. Frey HealthPartners

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