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Genetics

D-Index
62
Citations
13248
World Ranking
2983
National Ranking
1303

Overview

Perry B. Hackett is affiliated with the University of Minnesota in the United States. Their research spans several key fields within the biological sciences, with a primary focus on biochemistry, genetics, and molecular biology, as well as agricultural and biological sciences.

Their recent scientific contributions feature topics including CRISPR and genetic engineering, animal genetics and reproduction, and genetically modified organisms research. They have also worked in areas such as neural dynamics and brain function, functional brain connectivity studies, advanced neuroimaging techniques and applications, and animal disease management and epidemiology.

Hackett's work has been published in a variety of venues, demonstrating a multidisciplinary approach. Frequent publication venues include Trends in Biotechnology, Molecular Genetics and Metabolism, National Science Review, Frontiers of Agricultural Science and Engineering, and Scientific Reports.

Recent papers authored or coauthored by Hackett cover topics such as regulatory frameworks, safety, and social acceptance related to genetically modified animals. Selected papers include:

  • "Social acceptance for commercialization of genetically modified food animals," 2021, National Science Review
  • "Safety evaluation of transgenic and genome-edited food animals," 2021, Trends in Biotechnology
  • "Regulatory issues for genetically modified animals," 2020, Frontiers of Agricultural Science and Engineering
  • "Mapping brain networks in MPS I mice and their restoration following gene therapy," 2023, Scientific Reports
  • "Meeting report on the 2019 international symposium of molecular design breeding in animals (Yangling, China) with the consensus on genome-editing agricultural animals and their regulation," 2020, Transgenic Research

Hackett collaborates regularly with several researchers, including Ziyao Fan, Tad S. Sonstegard, Kui Li, Wei Zhu, and Xiaohong Zhu. Collaboration patterns reflect overlapping interests in genetic engineering and animal biotechnology.

The scope of Hackett's research integrates molecular biology and genetics with applied agricultural sciences, focusing on the intersection of advanced biotechnologies and regulatory and social considerations. This includes technical evaluations of genome editing methods in food animals and broader analyses of commercialization and regulatory landscapes.

Best Publications

  • Molecular Reconstruction of Sleeping Beauty, a Tc1-like Transposon from Fish, and Its Transposition in Human Cells

    Zoltán Ivics;Perry B Hackett;Ronald H Plasterk;Zsuzsanna Izsvák;Zsuzsanna Izsvák

  • Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells

    Partow Kebriaei;Harjeet Singh;M. Helen Huls;Matthew J. Figliola

  • Gene Transfer into Genomes of Human Cells by the Sleeping Beauty Transposon System

    Aron M Geurts;Ying Yang;Karl J Clark;Geyi Liu

  • Harnessing a high cargo-capacity transposon for genetic applications in vertebrates.

    Darius Balciunas;Kirk J Wangensteen;Andrew Wilber;Jason Bell

  • Efficient nonmeiotic allele introgression in livestock using custom endonucleases

    Wenfang Tan;Daniel F. Carlson;Cheryl A. Lancto;John R. Garbe

  • Redirecting Specificity of T-Cell Populations For CD19 Using the Sleeping Beauty System

    Harjeet Singh;Pallavi R. Manuri;Simon Olivares;Navid Dara

  • Structure-function analysis of the inverted terminal repeats of the sleeping beauty transposon.

    Zongbin Cui;Aron M. Geurts;Geyi Liu;Christopher D. Kaufman

  • Efficient gene delivery and gene expression in zebrafish using the Sleeping Beauty transposon.

    Ann E Davidson;Darius Balciunas;Deanna Mohn;Jennifer Shaffer

  • A Transposon and Transposase System for Human Application

    Perry B. Hackett;David A. Largaespada;Laurence J.N. Cooper

  • Mammalian germ-line transgenesis by transposition

    Adam J. Dupuy;Karl Clark;Corey M. Carlson;Sabine Fritz

  • Aquaculture genomics, genetics and breeding in the United States: current status, challenges, and priorities for future research

    Hisham Abdelrahman;Mohamed ElHady;Acacia Alcivar-Warren;Standish Allen

  • Moesin1 and Ve-cadherin are required in endothelial cells during in vivo tubulogenesis.

    Ying Wang;Mark S. Kaiser;Jon D. Larson;Aidas Nasevicius

  • Identification of functional domains and evolution of Tc1-like transposable elements

    Zoltan Ivics;Zsuzsanna Izsvak;Zsuzsanna Izsvak;Adam Minter;Perry B. Hackett

  • Dna-based transposon system for introducing nucleic acid into dna of cell

    Perry B Hackett;ビー. ハケット,ペリー;Zoltan Ivics;イフィックス,ツォルタン

  • Phenotypic correction and long-term expression of factor VIII in hemophilic mice by immunotolerization and nonviral gene transfer using the Sleeping Beauty transposon system

    John R. Ohlfest;Joel L. Frandsen;Sabine Fritz;Paul D. Lobitz

  • The Sleeping Beauty transposon system: a non-viral vector for gene therapy

    Elena L. Aronovich;R. Scott McIvor;Perry B. Hackett

  • Preferential delivery of the Sleeping Beauty transposon system to livers of mice by hydrodynamic injection

    Jason B Bell;Kelly M Podetz-Pedersen;Elena L Aronovich;Lalitha R Belur

  • Sleeping Beauty Transposon‐Mediated Gene Therapy for Prolonged Expression

    Perry B. Hackett;Stephen C. Ekker;David A. Largaespada;R. Scott McIvor

  • Target-site preferences of Sleeping Beauty transposons.

    Geyi Liu;Aron M. Geurts;Kojiro Yae;A.R. Srinivasan

  • Precision Editing of Large Animal Genomes

    Wenfang Spring Tan;Daniel F Carlson;Mark W Walton;Scott C Fahrenkrug

Frequent Co-Authors

R. Scott McIvor
R. Scott McIvor University of Minnesota
David A. Largaespada
David A. Largaespada University of Minnesota
Zsuzsanna Izsvák
Zsuzsanna Izsvák Max Delbrück Center for Molecular Medicine
Laurence J.N. Cooper
Laurence J.N. Cooper The University of Texas MD Anderson Cancer Center
Anthony J. Faras
Anthony J. Faras University of Minnesota
Zhanjiang Liu
Zhanjiang Liu Syracuse University
Aron M. Geurts
Aron M. Geurts Medical College of Wisconsin
Richard E. Champlin
Richard E. Champlin The University of Texas MD Anderson Cancer Center
Elizabeth J. Shpall
Elizabeth J. Shpall The University of Texas MD Anderson Cancer Center
Partow Kebriaei
Partow Kebriaei The University of Texas MD Anderson Cancer Center

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