His primary areas of investigation include Transforming growth factor, Cell biology, Internal medicine, Endocrinology and Plasmin. He usually deals with Transforming growth factor and limits it to topics linked to Receptor and Cell type and Sp1 transcription factor. The various areas that he examines in his Cell biology study include Endothelial stem cell, Platelet Endothelial Cell Adhesion Molecule and Immunoglobulin superfamily.
The concepts of his Internal medicine study are interwoven with issues in Transfection, Retinoic acid and Liver regeneration. His research in Plasmin focuses on subjects like Plasminogen activator, which are connected to Biochemistry, Retinoid, Midkine and Tissue transglutaminase. His Retinoic acid receptor study also includes
Soichi Kojima mostly deals with Biochemistry, Cancer research, Cell biology, Transforming growth factor and Hepatic stellate cell. His Biochemistry study combines topics in areas such as Plasminogen activator and Molecular biology. Soichi Kojima has researched Cancer research in several fields, including Retinoid, Retinoid X receptor alpha, Retinoic acid and Signal transduction.
His studies in Cell biology integrate themes in fields like Steatohepatitis, Angiogenesis and Cytosol. In his work, Antibody is strongly intertwined with Protease, which is a subfield of Transforming growth factor. He interconnects Fibrosis and Hepatic fibrosis in the investigation of issues within Hepatic stellate cell.
His primary scientific interests are in Cancer research, Molecular biology, Hepatic stellate cell, Tissue transglutaminase and Liver injury. His Cancer research research is multidisciplinary, relying on both Apoptosis, Signal transduction, Cancer stem cell and Cell growth. His biological study spans a wide range of topics, including Liver function and Urea cycle.
His Hepatic stellate cell research is multidisciplinary, incorporating perspectives in Oxidative stress, Reactive oxygen species and Arachidonic acid. Biochemistry covers Soichi Kojima research in Reactive oxygen species. His Tissue transglutaminase study combines topics from a wide range of disciplines, such as In vivo and Cell biology.
Soichi Kojima focuses on Cancer research, Vascular endothelial growth factor, Cell growth, Cancer and Liver cancer. His Cancer research research integrates issues from Integrin, Platelet Endothelial Cell Adhesion Molecule, Signal transduction and Endothelial dysfunction. His Vascular endothelial growth factor research incorporates themes from Endothelial stem cell, Transforming growth factor, Angiogenesis and Extracellular.
His Cell growth study which covers Transcriptome that intersects with Hepatic stellate cell and Molecular biology. His work carried out in the field of Hepatic stellate cell brings together such families of science as Cell culture, Liver injury and Reactive oxygen species, Biochemistry. His work focuses on many connections between Molecular biology and other disciplines, such as Cell activation, that overlap with his field of interest in Regulation of gene expression, Cap analysis gene expression, Genome and Gene expression profiling.
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A promoter-level mammalian expression atlas
Alistair R.R. Forrest;Hideya Kawaji;Michael Rehli;J. Kenneth Baillie.
Nature (2014)
An atlas of human long non-coding RNAs with accurate 5′ ends
Chung Chau Hon;Jordan A. Ramilowski;Jayson Harshbarger;Nicolas Bertin;Nicolas Bertin.
Nature (2017)
Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells
Erik Arner;Carsten O. Daub;Kristoffer Vitting-Seerup;Robin Andersson.
Science (2015)
Requirement for transglutaminase in the activation of latent transforming growth factor-beta in bovine endothelial cells.
S Kojima;K Nara;D B Rifkin.
Journal of Cell Biology (1993)
Lipoprotein (a) inhibits the generation of transforming growth factor beta: an endogenous inhibitor of smooth muscle cell migration.
Soichi Kojima;Peter C. Harpel;Daniel B. Rifkin.
Journal of Cell Biology (1991)
Transcriptional activation of endoglin and transforming growth factor-β signaling components by cooperative interaction between Sp1 and KLF6: their potential role in the response to vascular injury
Luisa M. Botella;Tilman Sánchez-Elsner;Francisco Sanz-Rodriguez;Soichi Kojima.
Blood (2002)
Retinoids exacerbate rat liver fibrosis by inducing the activation of latent TGF‐β in liver stellate cells
Masataka Okuno;Hisataka Moriwaki;Shoko Imai;Yasutoshi Muto.
Hepatology (1997)
Midkine Enhances Fibrinolytic Activity of Bovine Endothelial Cells
Soichi Kojima;Hisako Muramatsu;Hiroshi Amanuma;Takashi Muramatsu.
Journal of Biological Chemistry (1995)
Prevention of rat hepatic fibrosis by the protease inhibitor, camostat mesilate, via reduced generation of active TGF-β
Masataka Okuno;Kuniharu Akita;Hisataka Moriwaki;Norifumi Kawada.
Gastroenterology (2001)
Retinoids in Cancer Chemoprevention
Masataka Okuno;Soichi Kojima;Rie Matsushima-Nishiwaki;Hisashi Tsurumi.
Current Cancer Drug Targets (2004)
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