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Biology and Biochemistry

D-Index
67
Citations
16960
World Ranking
8175
National Ranking
549

Overview

Soichi Kojima is affiliated with the RIKEN Center for Integrative Medical Sciences in Japan. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these fields, their work focuses notably on Molecular Biology, Epidemiology, Cell Biology, Cancer Research, and Hepatology.

The main research topics addressed by Kojima include:

  • Cancer, Hypoxia, and Metabolism
  • Hepatitis B Virus Studies
  • Endoplasmic Reticulum Stress and Disease
  • Blood properties and coagulation
  • Liver Disease Diagnosis and Treatment
  • RNA Interference and Gene Delivery
  • Cancer, Lipids, and Metabolism

Kojima has published extensively, with notable papers including:

  • Lipid desaturation-associated endoplasmic reticulum stress regulates MYCN gene expression in hepatocellular carcinoma cells, 2020, Cell Death and Disease
  • Inhibition of Ganglioside Synthesis Suppressed Liver Cancer Cell Proliferation through Targeting Kinetochore Metaphase Signaling, 2021, Metabolites
  • Imaging of the ex vivo transglutaminase activity in liver macrophages of sepsis mice, 2020, Analytical Biochemistry
  • Design, synthesis, and target identification of new hypoxia-inducible factor 1 (HIF-1) inhibitors containing 1-alkyl-1H-pyrazole-3-carboxamide moiety, 2021, Bioorganic & Medicinal Chemistry
  • Targeting transglutaminase 2 mediated exostosin glycosyltransferase 1 signaling in liver cancer stem cells with acyclic retinoid, 2023, Cell Death and Disease

The frequent publication venues of Kojima include:

  • Cell Death and Disease
  • Cell Death Discovery
  • Metabolites
  • Bioorganic & Medicinal Chemistry
  • International Journal of Cancer

Collaborations form an important component of Kojima's work. Key frequent co-authors include:

  • Xian-Yang Qin
  • Yutaka Furutani
  • Tomokazu Matsuura
  • Takahiro Masaki
  • Naoshi Dohmae

Best Publications

  • A promoter-level mammalian expression atlas

    Alistair R.R. Forrest;Hideya Kawaji;Michael Rehli;J. Kenneth Baillie

  • An atlas of human long non-coding RNAs with accurate 5′ ends

    Chung Chau Hon;Jordan A. Ramilowski;Jayson Harshbarger;Nicolas Bertin;Nicolas Bertin

  • Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells

    Erik Arner;Carsten O. Daub;Kristoffer Vitting-Seerup;Robin Andersson

  • The Organization of High-Affinity Ammonium Uptake in Arabidopsis Roots Depends on the Spatial Arrangement and Biochemical Properties of AMT1-Type Transporters

    Lixing Yuan;Dominique Loqué;Soichi Kojima;Sabine Rauch

  • Requirement for transglutaminase in the activation of latent transforming growth factor-beta in bovine endothelial cells.

    S Kojima;K Nara;D B Rifkin

  • The Electronic Plant Gene Register

    Matthias Schmidt;Juergen Feierabend;Ya-Hsuan Hsu;Kin-Ying To

  • Ammonium Triggers Lateral Root Branching in Arabidopsis in an AMMONIUM TRANSPORTER1;3-Dependent Manner

    Joni E. Lima;Soichi Kojima;Soichi Kojima;Hideki Takahashi;Nicolaus von Wirén;Nicolaus von Wirén

  • Lipoprotein (a) inhibits the generation of transforming growth factor beta: an endogenous inhibitor of smooth muscle cell migration.

    Soichi Kojima;Peter C. Harpel;Daniel B. Rifkin

  • FANTOM5 CAGE profiles of human and mouse samples

    Shuhei Noguchi;Takahiro Arakawa;Shiro Fukuda;Masaaki Furuno

  • CLE-CLAVATA1 peptide-receptor signaling module regulates the expansion of plant root systems in a nitrogen-dependent manner

    Takao Araya;Mayu Miyamoto;Juliarni Wibowo;Akinori Suzuki

  • Additive contribution of AMT1;1 and AMT1;3 to high‐affinity ammonium uptake across the plasma membrane of nitrogen‐deficient Arabidopsis roots

    Dominique Loqué;Lixing Yuan;Soichi Kojima;Alain Gojon

  • Transcriptional activation of endoglin and transforming growth factor-β signaling components by cooperative interaction between Sp1 and KLF6: their potential role in the response to vascular injury

    Luisa M. Botella;Tilman Sánchez-Elsner;Francisco Sanz-Rodriguez;Soichi Kojima

  • Retinoids exacerbate rat liver fibrosis by inducing the activation of latent TGF-beta in liver stellate cells.

    Masataka Okuno;Hisataka Moriwaki;Shoko Imai;Yasutoshi Muto

  • Role of transglutaminase 2 in liver injury via cross-linking and silencing of transcription factor Sp1.

    Hideki Tatsukawa;Yayoi Fukaya;Gordon Frampton;Antonio Martinez-Fuentes

  • Retinoids in Cancer Chemoprevention

    Masataka Okuno;Soichi Kojima;Rie Matsushima-Nishiwaki;Hisashi Tsurumi

  • Prevention of rat hepatic fibrosis by the protease inhibitor, camostat mesilate, via reduced generation of active TGF-β

    Masataka Okuno;Kuniharu Akita;Hisataka Moriwaki;Norifumi Kawada

  • Midkine Enhances Fibrinolytic Activity of Bovine Endothelial Cells

    Soichi Kojima;Hisako Muramatsu;Hiroshi Amanuma;Takashi Muramatsu

  • Transcriptional activation of urokinase by the Krüppel-like factor Zf9/COPEB activates latent TGF-β1 in vascular endothelial cells

    Soichi Kojima;Shinichi Hayashi;Kentaro Shimokado;Yasuhiro Suzuki

  • Increased Rubisco content in transgenic rice transformed with the 'sense' rbcS gene.

    Yuji Suzuki;Maki Ohkubo;Hanako Hatakeyama;Keiko Ohashi

  • Phosphorylation of retinoid X receptor alpha at serine 260 impairs its metabolism and function in human hepatocellular carcinoma.

    Rie Matsushima-Nishiwaki;Masataka Okuno;Seiji Adachi;Tetsuro Sano

Frequent Co-Authors

Hisataka Moriwaki
Hisataka Moriwaki Gifu University
Scott L. Friedman
Scott L. Friedman Icahn School of Medicine at Mount Sinai
Yuji Inada
Yuji Inada Toin University of Yokohama
Daniel B. Rifkin
Daniel B. Rifkin New York University
Alistair R. R. Forrest
Alistair R. R. Forrest Harry Perkins Institute of Medical Research
Christine A. Wells
Christine A. Wells University of Melbourne
Timo Lassmann
Timo Lassmann Telethon Kids Institute

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