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Biology and Biochemistry

D-Index
121
Citations
65320
World Ranking
599
National Ranking
384

Overview

Daniel B. Rifkin is affiliated with New York University in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant contributions to medicine. The scientist's work spans multiple subfields including molecular biology, endocrinology, diabetes and metabolism, rheumatology, physiology, and genetics.

Rifkin's research explores key topics such as TGF-β signaling in diseases, growth hormone and insulin-like growth factors, osteoarthritis treatment and mechanisms, muscle physiology and disorders, connective tissue disorders research, cancer-related gene regulation, and the interplay of cancer, hypoxia, and metabolism.

Their publication record includes several papers, notably:

  • The role of LTBPs in TGF beta signaling (2021, Developmental Dynamics)
  • Intraarticular injection of liposomal adenosine reduces cartilage damage in established murine and rat models of osteoarthritis (2020, Scientific Reports)
  • Osteoblastic monocyte chemoattractant protein-1 (MCP-1) mediation of parathyroid hormone's anabolic actions in bone implicates TGF-β signaling (2020, Bone)
  • Latent transforming growth factor β binding protein 3 controls adipogenesis (2022, Matrix Biology)
  • Collagen type VI regulates TGF-β bioavailability in skeletal muscle in mice (2025, Journal of Clinical Investigation)

Rifkin has co-authored frequently with several researchers, including:

  • Nalani Sachan
  • Karan Singh
  • Payam Mohassel
  • Hailey Hearn
  • Kory R. Johnson

Their work has appeared in specialized publication venues such as Matrix Biology, bioRxiv (Cold Spring Harbor Laboratory), Developmental Dynamics, Scientific Reports, and Bone.

Best Publications

  • The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis.

    John S Munger;Xiaozhu Huang;Hisaaki Kawakatsu;Mark J.D Griffiths

  • Making sense of latent TGFβ activation

    Justin P. Annes;John S. Munger;Daniel B Rifkin

  • Specific Microbiota Direct the Differentiation of IL-17-Producing T-Helper Cells in the Mucosa of the Small Intestine

    Ivaylo Ivanov Ivanov;Rosa de Llanos Frutos;Nicolas Manel;Keiji Yoshinaga

  • Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome.

    Jennifer P. Habashi;Daniel P. Judge;Tammy M. Holm;Ronald D. Cohn

  • A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2

    Bart L Loeys;Junji Chen;Enid R Neptune;Daniel P Judge

  • Biology and biochemistry of proteinases in tumor invasion

    P. Mignatti;D. B. Rifkin

  • Myofibroblast contraction activates latent TGF-β1 from the extracellular matrix

    Pierre-Jean Wipff;Daniel B. Rifkin;Jean-Jacques Meister;Boris Hinz

  • Recent developments in the cell biology of basic fibroblast growth factor.

    D B Rifkin;D Moscatelli

  • Biological roles of fibroblast growth factor-2.

    Andreas Bikfalvi;Sharon Klein;Giuseppe Pintucci;Daniel B. Rifkin

  • Cell-associated plasminogen activation: regulation and physiological functions.

    Olli Saksela;Daniel B. Rifkin

  • Endothelial Cell-derived Heparan Sulfate Binds Basic Fibroblast Growth Factor and Protects It from Proteolytic Degradation

    Olli Saksela;David Moscatelli;Andreas Sommer;Daniel B. Rifkin

  • Fibroblast Growth Factor-2 (FGF-2) Induces Vascular Endothelial Growth Factor (VEGF) Expression in the Endothelial Cells of Forming Capillaries: An Autocrine Mechanism Contributing to Angiogenesis

    Graziano Seghezzi;Sundeep Patel;Christine J. Ren;Anna Gualandris

  • Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-beta 1-like molecule by plasmin during co-culture.

    Y Sato;D B Rifkin

  • An assay for transforming growth factor-β using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct

    M. Abe;J.G. Harpel;C.N. Metz;I. Nunes

  • An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. I. Chick embryo fibroblast cultures transformed by avian RNA tumor viruses.

    J. C. Unkeless;A. Tobia;L. Ossowski;J. P. Quigley

  • Tumor invasion through the human amniotic membrane: Requirement for a proteinase cascade

    Paolo Mignatti;Edith Robbins;Daniel B. Rifkin

  • Release of basic fibroblast growth factor-heparan sulfate complexes from endothelial cells by plasminogen activator-mediated proteolytic activity.

    O Saksela;D B Rifkin

  • Autocrine activities of basic fibroblast growth factor: regulation of endothelial cell movement, plasminogen activator synthesis, and DNA synthesis.

    Y Sato;D B Rifkin

  • Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor.

    Philip A. Dennis;Daniel B. Rifkin

  • Latent transforming growth factor-β: Structural features and mechanisms of activation

    John S. Munger;John G. Harpel;Pierre-Emmanuel Gleizes;Roberta Mazzieri

Frequent Co-Authors

David Moscatelli
David Moscatelli New York University
Francesco Ramirez
Francesco Ramirez Icahn School of Medicine at Mount Sinai
Soichi Kojima
Soichi Kojima RIKEN Center for Integrative Medical Sciences
Yasufumi Sato
Yasufumi Sato Tohoku University
Lynn Y. Sakai
Lynn Y. Sakai Oregon Health & Science University
Robert Flaumenhaft
Robert Flaumenhaft Beth Israel Deaconess Medical Center
Harry C. Dietz
Harry C. Dietz Johns Hopkins University School of Medicine
Marco Presta
Marco Presta University of Brescia
James P. Quigley
James P. Quigley Scripps Research Institute
Pierre-Emmanuel Gleizes
Pierre-Emmanuel Gleizes Federal University of Toulouse Midi-Pyrénées

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