What is he best known for?
The fields of study he is best known for:
His primary areas of investigation include Fibrillin, Fibrillin Microfibrils, Fibrillin-2, Fibrillins and Marfan syndrome.
His research in Fibrillin tackles topics such as Molecular biology which are related to areas like Fibulin.
His Fibrillin Microfibrils study is within the categories of Cell biology and Biochemistry.
He has included themes like Elastin, Biophysics, Elastic fiber assembly and Anatomy in his Fibrillin-2 study.
Fibrillins is a subfield of Extracellular matrix that Lynn Y. Sakai investigates.
His research in Marfan syndrome intersects with topics in Mutation, Missense mutation and Mutant.
His most cited work include:
- Marfan syndrome caused by a recurrent de novo missense mutation in the fibrillin gene. (1538 citations)
- Marfan syndrome caused by a recurrent de novo missense mutation in the fibrillin gene. (1538 citations)
- Dysregulation of TGF-β activation contributes to pathogenesis in Marfan syndrome (1120 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Fibrillin, Cell biology, Fibrillin Microfibrils, Fibrillins and Biochemistry.
His Fibrillin-2 study in the realm of Fibrillin interacts with subjects such as Microfibril.
His Cell biology research includes elements of Growth factor and Bone morphogenetic protein.
His Fibrillin Microfibrils study also includes fields such as
- Biophysics which intersects with area such as Elastin,
- Molecular biology which intersects with area such as Antibody and Thrombospondin.
His Fibrillins study integrates concerns from other disciplines, such as Fibronectin, Recombinant DNA and Protein precursor.
His studies deal with areas such as Epitope and Transforming growth factor as well as Biochemistry.
He most often published in these fields:
- Fibrillin (72.22%)
- Cell biology (34.44%)
- Fibrillin Microfibrils (36.67%)
What were the highlights of his more recent work (between 2012-2021)?
- Fibrillin (72.22%)
- Marfan syndrome (19.44%)
- Pathology (24.44%)
In recent papers he was focusing on the following fields of study:
Lynn Y. Sakai mostly deals with Fibrillin, Marfan syndrome, Pathology, Cell biology and Internal medicine.
His Fibrillin Microfibrils and Fibrillins study in the realm of Fibrillin connects with subjects such as Microfibril.
His study in Marfan syndrome is interdisciplinary in nature, drawing from both Aneurysm, Aortic aneurysm, Aorta, Pregnancy and Phenotype.
His research in the fields of Connective tissue overlaps with other disciplines such as Tobacco smoke exposure, Fragment and In patient.
The Cell biology study combines topics in areas such as Vesicle and Secretion.
His Internal medicine research incorporates themes from Endocrinology and Cardiology.
Between 2012 and 2021, his most popular works were:
- FBN1: The disease-causing gene for Marfan syndrome and other genetic disorders. (93 citations)
- Latent TGF-β binding protein 4 promotes elastic fiber assembly by interacting with fibulin-5. (87 citations)
- Intracellular mechanisms of molecular recognition and sorting for transport of large extracellular matrix molecules (71 citations)
In his most recent research, the most cited papers focused on:
His main research concerns Fibrillin, Marfan syndrome, Cell biology, COPII and Microfibril.
Lynn Y. Sakai works on Fibrillin which deals in particular with Elastic fiber assembly.
The various areas that Lynn Y. Sakai examines in his Marfan syndrome study include Fibrosis, Pathology and Aortic aneurysm.
His Pathology research incorporates elements of Ex vivo, In vivo, Cardiomyopathy and Anatomy.
His Microfibril research overlaps with other disciplines such as Arachnodactyly, Genetics, Weill–Marchesani syndrome, Ectopia lentis and Fibrillin Microfibrils.
The study incorporates disciplines such as Mechanotransduction, Fibrillins, Growth factor and Scaffold in addition to Arachnodactyly.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
