D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 84 Citations 22,178 244 World Ranking 1427 National Ranking 844

Research.com Recognitions

Awards & Achievements

2007 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

His main research concerns Elastin, Biochemistry, Extracellular matrix, Tropoelastin and Elastic fiber. His biological study spans a wide range of topics, including Molecular biology, Lysyl oxidase and Anatomy. The subject of his Extracellular matrix research is within the realm of Cell biology.

His Cell biology research also works with subjects such as

  • Laminin most often made with reference to Receptor,
  • Cell which intersects with area such as Immunology. His studies in Tropoelastin integrate themes in fields like Heparan sulfate and Glycosaminoglycan. His Elastic fiber study combines topics from a wide range of disciplines, such as Cartilaginous fish and Blood pressure.

His most cited work include:

  • Elastin is an essential determinant of arterial morphogenesis (627 citations)
  • Vascular Extracellular Matrix and Arterial Mechanics (598 citations)
  • Extracellular matrix 4: the elastic fiber. (514 citations)

What are the main themes of his work throughout his whole career to date?

Elastin, Extracellular matrix, Biochemistry, Tropoelastin and Cell biology are his primary areas of study. His study in Elastin is interdisciplinary in nature, drawing from both Molecular biology, Internal medicine and Elastic fiber, Anatomy. His Anatomy research includes themes of Artery, Circulatory system and Aorta.

His studies deal with areas such as Extracellular, Endocrinology, Matrix and Immunology as well as Extracellular matrix. His Tropoelastin study integrates concerns from other disciplines, such as Cell culture, Biophysics and Enzyme. The concepts of his Cell biology study are interwoven with issues in Phenotype, Glycoprotein, Ligamentum nuchae, Growth factor and Cell type.

He most often published in these fields:

  • Elastin (54.23%)
  • Extracellular matrix (29.15%)
  • Biochemistry (27.99%)

What were the highlights of his more recent work (between 2012-2021)?

  • Elastin (54.23%)
  • Extracellular matrix (29.15%)
  • Internal medicine (17.78%)

In recent papers he was focusing on the following fields of study:

Robert P. Mecham mainly investigates Elastin, Extracellular matrix, Internal medicine, Cell biology and Endocrinology. His Elastin research entails a greater understanding of Pathology. His research integrates issues of Biophysics, Lung, Notch signaling pathway and Function in his study of Extracellular matrix.

Within one scientific family, Robert P. Mecham focuses on topics pertaining to Glycoprotein under Cell biology, and may sometimes address concerns connected to Phenotype. His Endocrinology research focuses on Lysyl oxidase and how it relates to Aortic aneurysm. His Elastic fiber study incorporates themes from Tropoelastin and Cutis laxa.

Between 2012 and 2021, his most popular works were:

  • Loss of function mutation in LOX causes thoracic aortic aneurysm and dissection in humans. (77 citations)
  • Development, composition, and structural arrangements of the ciliary zonule of the mouse. (53 citations)
  • Hypotension due to Kir6.1 gain-of-function in vascular smooth muscle. (44 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

Robert P. Mecham focuses on Elastin, Extracellular matrix, Anatomy, Internal medicine and Pathology. His study brings together the fields of Elastic fiber and Elastin. The various areas that Robert P. Mecham examines in his Extracellular matrix study include Lung, Lipoprotein and Biomedical engineering.

In his research on the topic of Anatomy, Biophysics is strongly related with Aorta. His Internal medicine research integrates issues from Endocrinology and Cardiology. The Pathology study which covers Fibrillin that intersects with Immunology, Transforming growth factor beta and Transforming growth factor.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Vascular Extracellular Matrix and Arterial Mechanics

Jessica E. Wagenseil;Robert P. Mecham.
Physiological Reviews (2009)

891 Citations

Elastin is an essential determinant of arterial morphogenesis

Dean Y. Li;Benjamin Brooke;Elaine C. Davis;Robert P. Mecham.
Nature (1998)

831 Citations

Extracellular matrix 4: the elastic fiber.

Joel Rosenbloom;William R. Abrams;Robert Mecham.
The FASEB Journal (1993)

697 Citations

Chemotactic activity of elastin-derived peptides.

R. M. Senior;G. L. Griffin;Robert Mecham.
Journal of Clinical Investigation (1980)

601 Citations

TGF-β–dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome

Connie M. Ng;Alan Cheng;Loretha A. Myers;Francisco Martinez-Murillo.
Journal of Clinical Investigation (2004)

597 Citations

Production and localization of 92-kilodalton gelatinase in abdominal aortic aneurysms. An elastolytic metalloproteinase expressed by aneurysm-infiltrating macrophages.

R. W. Thompson;D. R. Holmes;R. A. Mertens;Shixiong Liao.
Journal of Clinical Investigation (1995)

520 Citations

Extracellular matrix assembly and structure

Peter D. Yurchenco;David E. Birk;Robert P. Mecham.
(1994)

511 Citations

Elastin fragments drive disease progression in a murine model of emphysema

A. McGarry Houghton;Pablo A. Quintero;David L. Perkins;Dale K. Kobayashi.
Journal of Clinical Investigation (2006)

465 Citations

Val-Gly-Val-Ala-Pro-Gly, a repeating peptide in elastin, is chemotactic for fibroblasts and monocytes.

R M Senior;G L Griffin;R P Mecham;D S Wrenn.
Journal of Cell Biology (1984)

435 Citations

CELLULAR AND MOLECULAR MECHANISMS OF PULMONARY VASCULAR REMODELING

K. R. Stenmark;R. P. Mecham.
Annual Review of Physiology (1997)

431 Citations

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