World's Best Scientists 2026 revealed!
Jay D. Humphrey

Jay D. Humphrey

Award Badge
Engineering and Technology
USA
2026

D-Index & Metrics

Engineering and Technology

D-Index
94
Citations
33540
World Ranking
207
National Ranking
76

Research.com Recognitions

  • 2026 - Research.com Engineering and Technology in United States Leader Award
  • 2025 - Research.com Engineering and Technology in United States Leader Award
  • 2008 - Fellow of the American Society of Mechanical Engineers
  • 2001 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Jay D. Humphrey is affiliated with Yale University in the United States and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research focuses significantly on areas such as Pulmonary and Respiratory Medicine, Biomedical Engineering, Surgery, Cardiology and Cardiovascular Medicine, and Genetics.

The main topics of their work include:

  • Elasticity and Material Modeling
  • Aortic Disease and Treatment Approaches
  • Aortic Aneurysm Repair Treatments
  • Connective Tissue Disorders Research
  • Cellular Mechanics and Interactions
  • Electrospun Nanofibers in Biomedical Applications
  • Cardiovascular Health and Disease Prevention

Humphrey has published research in a variety of venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biomechanics and Modeling in Mechanobiology
  • arXiv (Cornell University)
  • Arteriosclerosis Thrombosis and Vascular Biology
  • Journal of The Royal Society Interface

Recent papers authored or co-authored by Humphrey include:

  • "Arterial Stiffness and Cardiovascular Risk in Hypertension" (2021), published in Circulation Research
  • "Smooth Muscle Cell Reprogramming in Aortic Aneurysms" (2020), published in Cell Stem Cell
  • "Vascular Mechanobiology: Homeostasis, Adaptation, and Disease" (2021), published in Annual Review of Biomedical Engineering
  • "Non-invasive Inference of Thrombus Material Properties with Physics-informed Neural Networks" (2020), published in Computer Methods in Applied Mechanics and Engineering
  • "Mechanisms of Vascular Remodeling in Hypertension" (2020), published in American Journal of Hypertension

Frequent co-authors who have collaborated with Humphrey include:

  • Abhay B. Ramachandra
  • Cristina Cavinato
  • Sae-Il Murtada
  • George Tellides
  • Marcos Latorre

In addition to journal articles, Humphrey has also contributed to book publications such as "Style and Ethics of Communication in Science and Engineering" published by Morgan & Claypool Publishers in 2023.

Throughout their career, Humphrey's recognitions include being named Fellow of the American Society of Mechanical Engineers in 2008 and Fellow of the Indian National Academy of Engineering (INAE) in 2001.

Best Publications

  • Mechanotransduction and extracellular matrix homeostasis

    Jay D. Humphrey;Eric R. Dufresne;Martin A. Schwartz

  • Cardiovascular Solid Mechanics: Cells, Tissues, and Organs

    JD Humphrey;M Epstein

  • A CONSTRAINED MIXTURE MODEL FOR GROWTH AND REMODELING OF SOFT TISSUES

    J. D. Humphrey;K. R. Rajagopal

  • Arterial Stiffness and Cardiovascular Risk in Hypertension.

    Pierre Boutouyrie;Phil Chowienczyk;Jay D. Humphrey;Gary F. Mitchell

  • Cardiovascular solid mechanics

    Jay Dowell Humphrey

  • Perspectives on biological growth and remodeling

    D. Ambrosi;G.A. Ateshian;E.M. Arruda;S.C. Cowin

  • Determination of a constitutive relation for passive myocardium: I. A new functional form.

    J. D. Humphrey;R. K. Strumpf;F. C. P. Yin

  • Heat-induced changes in the mechanics of a collagenous tissue: isothermal, isotonic shrinkage.

    S. S. Chen;N. T. Wright;J. D. Humphrey

  • MECHANICS OF THE ARTERIAL WALL: REVIEW AND DIRECTIONS

    Jay D. Humphrey

  • Intracranial and Abdominal Aortic Aneurysms: Similarities, Differences, and Need for a New Class of Computational Models

    J.D. Humphrey;C.A. Taylor

  • Mechanisms of Arterial Remodeling in Hypertension: Coupled Roles of Wall Shear and Intramural Stress

    Jay D. Humphrey

  • Mechanics, mechanobiology, and modeling of human abdominal aorta and aneurysms.

    Jay D. Humphrey;Gerhard Holzapfel;Gerhard Holzapfel

  • Determination of a constitutive relation for passive myocardium: II. Parameter estimation.

    J. D. Humphrey;R. K. Strumpf;F. C. P. Yin

  • Stress-Modulated Growth, Residual Stress, and Vascular Heterogeneity

    Larry A. Taber;Jay D. Humphrey

  • Theory of small on large: Potential utility in computations of fluid–solid interactions in arteries

    S. Baek;R.L. Gleason;K.R. Rajagopal;J.D. Humphrey

  • Heat-induced changes in the mechanics of a collagenous tissue

    S.S Chen;J.D Humphrey

  • A Theoretical Model of Enlarging Intracranial Fusiform Aneurysms

    S. Baek;K. R. Rajagopal;J. D. Humphrey

  • Fundamental role of axial stress in compensatory adaptations by arteries.

    J.D. Humphrey;J.F. Eberth;W.W. Dye;R.L. Gleason

  • Phenomenological evolution equations for heat-induced shrinkage of a collagenous tissue

    S.S. Chen;N.T. Wright;J.D. Humphrey

  • On constitutive relations and finite deformations of passive cardiac tissue: I. A pseudostrain-energy function.

    J. D. Humphrey;F. C. P. Yin

Frequent Co-Authors

Gerhard A. Holzapfel
Gerhard A. Holzapfel Graz University of Technology
George Em Karniadakis
George Em Karniadakis Brown University
Alison L. Marsden
Alison L. Marsden Stanford University
Martin A. Schwartz
Martin A. Schwartz Yale University
Stéphane Avril
Stéphane Avril École des Mines de Saint-Étienne
Francesco Ramirez
Francesco Ramirez Icahn School of Medicine at Mount Sinai
Dianna M. Milewicz
Dianna M. Milewicz The University of Texas Health Science Center at Houston
David G. Harrison
David G. Harrison Vanderbilt University
Daniel B. Rifkin
Daniel B. Rifkin New York University
Jason A. Burdick
Jason A. Burdick University of Colorado Boulder

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